Simultaneous Sensing of H2S and ATP with a Two-Photon Fluorescent Probe in Alzheimer’s Disease: toward Understanding Why H2S Regulates Glutamate-Induced ATP Dysregulation

Alzheimer's disease is causally associated with mitochondrial dysfunction

(2022) Shea J Andrews   Alzheimers & Dementia

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration

(2022) Tara E. Tracy et al.   CELL

Near-infrared fluorescent probe for hydrogen sulfide: high-fidelity ferroptosis evaluation in vivo during stroke

(2022) Tianyu Liang et al.   Chemical Science

Hydrogen sulfide is neuroprotective in Alzheimer’s disease by sulfhydrating GSK3β and inhibiting Tau hyperphosphorylation

(2021) Daniel Giovinazzo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Activatable Near-Infrared Fluorescence Hydrogen Sulfide (H2S) Donor for Imaging H2S Release and Inhibiting Inflammation in Cells

(2021) Xinyue Zhao et al.   ANALYTICAL CHEMISTRY

Near-Infrared Mitochondria-Targetable Fluorescent Probe for High-Contrast Bioimaging of H2S

(2021) Shengyi Gong et al.   ANALYTICAL CHEMISTRY

Bayes analysis supports null hypothesis of anti‐amyloid beta therapy in Alzheimer's disease

(2021) Edo Richard et al.   Alzheimers & Dementia

Design and Development of a Bioorthogonal, Visualizable and Mitochondria‐Targeted Hydrogen Sulfide (H 2 S) Delivery System

(2021) Yinghan Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Glutamate Metabolism in Mitochondria is Closely Related to Alzheimer’s Disease

(2021) Jiayi Song et al.   JOURNAL OF ALZHEIMERS DISEASE

Dual-Channel Fluorescent Probe for the Simultaneous Monitoring of Peroxynitrite and Adenosine-5′-triphosphate in Cellular Applications

(2021) Luling Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Engineering a Reversible Fluorescent Probe for Real-Time Live-Cell Imaging and Quantification of Mitochondrial ATP

(2020) Tian-Bing Ren et al.   ANALYTICAL CHEMISTRY

Ultrafast Detection of Peroxynitrite in Parkinson’s Disease Models Using a Near-Infrared Fluorescent Probe

(2020) Qian Sun et al.   ANALYTICAL CHEMISTRY

Aralar Sequesters GABA into Hyperactive Mitochondria, Causing Social Behavior Deficits

(2020) Alexandros K. Kanellopoulos et al.   CELL

Real-Time Imaging and Simultaneous Quantification of Mitochondrial H2O2 and ATP in Neurons with a Single Two-Photon Fluorescence-Lifetime-Based Probe

(2020) Zhou Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Epileptic brain fluorescent imaging reveals apigenin can relieve the myeloperoxidase-mediated oxidative stress and inhibit ferroptosis

(2020) Chenwen Shao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A New Strategy: Distinguishable Multi-substance Detection, Multiple Pathway Tracing Based on a New Site Constructed by the Reaction Process and Its Tumor Targeting

(2020) Yongfei Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Specific Fluorescent Probe Based on “Protect–Deprotect” To Visualize the Norepinephrine Signaling Pathway and Drug Intervention Tracers

(2020) Na Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Interaction of human IAPP and Aβ1-42 aggravated the AD-related pathology and impaired the cognition in mice

(2020) Hai-Chao Chen et al.   EXPERIMENTAL NEUROLOGY

Rational Design of Near-Infrared AIE-Active Probes: In Situ Mapping of Amyloid-β Plaques with Ultra-Sensitivity and High-Fidelity

(2019) Wei Fu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease

(2019) D. Allan Butterfield et al.   NATURE REVIEWS NEUROSCIENCE

Illuminating the Function of the Hydroxyl Radical in the Brains of Mice with Depression Phenotypes by Two-Photon Fluorescence Imaging

(2019) Xin Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bright AIEgen–Protein Hybrid Nanocomposite for Deep and High‐Resolution In Vivo Two‐Photon Brain Imaging

(2019) Shaowei Wang et al.   ADVANCED FUNCTIONAL MATERIALS

Activatable Small-Molecule Photoacoustic Probes that Cross the Blood-Brain Barrier for Visualization of Copper(II) in Mice with Alzheimer's Disease

(2019) Shichao Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Development and Application of Carbonyl Sulfide-Based Donors for H2S Delivery

(2019) Carolyn M. Levinn et al.   ACCOUNTS OF CHEMICAL RESEARCH

Alzheimer Disease: An Update on Pathobiology and Treatment Strategies

(2019) Justin M. Long et al.   CELL

Evaluating Drug-Induced Liver Injury and Its Remission via Discrimination and Imaging of HClO and H2S with a Two-Photon Fluorescent Probe

(2018) Xiaoyun Jiao et al.   ANALYTICAL CHEMISTRY

O→S Relay Deprotection: A General Approach to Controllable Donors of Reactive Sulfur Species

(2018) Jianming Kang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Ratiometric Two-Photon Fluorescent Probe for Tracking Lysosomal ATP: Direct In Cellulo Observation of Lysosomal Membrane Fusion Processes

(2018) Yong Woong Jun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hydrogen sulfide inhibits ATP-induced neuroinflammation and Aβ 1–42 synthesis by suppressing the activation of STAT3 and cathepsin S

(2018) Lei Cao et al.   BRAIN BEHAVIOR AND IMMUNITY

A dual-function fluorescent probe for monitoring the degrees of hypoxia in living cells via the imaging of nitroreductase and adenosine triphosphate

(2018) Yu Fang et al.   CHEMICAL COMMUNICATIONS

Oxalate-curcumin–based probe for micro- and macroimaging of reactive oxygen species in Alzheimer’s disease

(2017) Jian Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Single Fluorescent Probe to Visualize Hydrogen Sulfide and Hydrogen Polysulfides with Different Fluorescence Signals

(2016) Wei Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent progress in the development of fluorescent, luminescent and colorimetric probes for detection of reactive oxygen and nitrogen species

(2016) Xiaoqiang Chen et al.   CHEMICAL SOCIETY REVIEWS

S- Sulfhydration of ATP synthase by hydrogen sulfide stimulates mitochondrial bioenergetics

(2016) Katalin Módis et al.   PHARMACOLOGICAL RESEARCH

A Multisite-Binding Switchable Fluorescent Probe for Monitoring Mitochondrial ATP Level Fluctuation in Live Cells

(2015) Lu Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hydrogen Sulfide: A Neuromodulator and Neuroprotectant in the Central Nervous System

(2014) Xingzhou Zhang et al.   ACS Chemical Neuroscience

Biometals and Their Therapeutic Implications in Alzheimer’s Disease

(2014) Scott Ayton et al.   Neurotherapeutics

A colorimetric and ratiometric fluorescent probe for the imaging of endogenous hydrogen sulphide in living cells and sulphide determination in mouse hippocampus

(2014) Ling Zhang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Oligomycin frames a common drug-binding site in the ATP synthase

(2012) J. Symersky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen sulfide (H2S) metabolism in mitochondria and its regulatory role in energy production

(2012) M. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fluorescent probes for sensing and imaging

(2011) Tasuku Ueno et al.   NATURE METHODS

Gases in the mitochondria

(2009) Pamela B.L. Pun et al.   MITOCHONDRION

Hydrogen sulfide is an endogenous stimulator of angiogenesis

(2009) A. Papapetropoulos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

11C-labelled PIB analogues as potential tracer agents for in vivo imaging of amyloid β in Alzheimer's disease

(2008) K. Serdons et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY