Editorial Material
Plant Sciences
Hazem S. Elshafie
Summary: This article summarizes the chemical composition and biological-pharmaceutical activities of plant essential oils (PEOs), and discusses their possible modes of action and influencing factors. It provides valuable insights into the application of PEOs.
Article
Polymer Science
Iolanda Corrado, Rocco Di Girolamo, Carlos Regalado-Gonzalez, Cinzia Pezzella
Summary: Plant-derived essential oils offer a green alternative to conventional antimicrobial agents in food preservation. Encapsulation in Polyhydroxyalkanoate-based nanoparticles provides an effective strategy for protecting and controlling the release of essential oils, contributing to food preservation.
Article
Materials Science, Multidisciplinary
Crisiane A. Marangon, Mirella Romanelli Bertolo, Virginia da C. Amaro Martins, Marcia Nitschke, Ana Maria de Guzzi Plepis
Summary: The study investigates natural emulsions of chitosan/gelatin containing pequi oil and their antimicrobial properties, offering a strategy for the development of natural compound emulsions as food additives. The results demonstrate the synergistic antimicrobial protection between oil and chitosan in the emulsions, highlighting their potential as food additives.
ACS APPLIED POLYMER MATERIALS
(2021)
Review
Biochemistry & Molecular Biology
Mohammad Mukarram, Sadaf Choudhary, Mo Ahamad Khan, Palmiro Poltronieri, M. Masroor A. Khan, Jamin Ali, Daniel Kurjak, Mohd Shahid
Summary: Lemongrass essential oil (LEO) contains various bioactive compounds that possess antifungal, antibacterial, antiviral, anticancer, and antioxidant properties. LEO is commercially exploited in pharmaceutical, cosmetics, and food preservations industries, and shows potential in cancer treatment.
Article
Food Science & Technology
Zhi-Jing Ni, Xin Wang, Yi Shen, Kiran Thakur, Jinzhi Han, Jian-Guo Zhang, Fei Hu, Zhao-Jun Wei
Summary: Essential oils, natural active compounds, have been widely used in food and pharmaceutical industries for their flavor and fragrance. Recent studies have shown significant biological activities and health benefits of essential oils, leading to their potential as safe alternative therapeutics in various industries.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Diana Obistioiu, Anca Hulea, Ileana Cocan, Ersilia Alexa, Monica Negrea, Iuliana Popescu, Viorel Herman, Ilinca Merima Imbrea, Gabriel Heghedus-Mindru, Mukhtar Adeiza Suleiman, Isidora Radulov, Florin Imbrea
Summary: The research aims to evaluate the chemical composition, antioxidant and anti-inflammatory activity, as well as antimicrobial activity of a commercial Boswellia essential oil. The findings demonstrate the oil's high antioxidant and antimicrobial potential against food-related pathogens, making it a good candidate for use in food, feed, or food-safety-related products.
Article
Food Science & Technology
Juliana Junqueira Pinelli, Heloisa Helena de Abreu Martins, Angelica Sousa Guimaraes, Silas Rodrigo Isidoro, Michelle Carlota Goncalves, Tatiana Silveira Junqueira de Moraes, Eduardo Mendes Ramos, Roberta Hilsdorf Piccoli
Summary: The study evaluated the antimicrobial activity of essential oils and their nanoemulsions against Clostridium sporogenes in mortadella with sodium nitrite reduction. Nanoemulsions were found to be more effective than individual essential oils in reducing vegetative cells. The combinations acted as antioxidants in the meat product without modifying its other technological characteristics.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Chemistry, Medicinal
Rafael Pereira da Cruz, Jose Walber Goncalves Castro, Debora Odilia Duarte Leite, Natalia Kelly Gomes de Carvalho, Jose Weverton Almeida-Bezerra, Raimundo Luiz Silva Pereira, Fazia Fernandes Galvao Rodrigues, Jose Jailson Lima Bezerra, Adrielle Rodrigues Costa, Edna Mori, Pablo Antonio Maia de Farias, Henrique Douglas Melo Coutinho, Maria Flaviana Bezerra Morais-Braga, Marcello Iriti, Jose Galberto Martins da Costa, Fabiola Fernandes Galvao Rodrigues
Summary: This study investigates the chemical composition of the essential oil of Acritopappus confertus leaves and its antimicrobial effects against pathogenic fungi and bacteria. The results demonstrate that the essential oil has antifungal properties, with significant inhibitory effects on certain fungal strains, and it also enhances the antimicrobial activity when used in combination with antibiotics.
Article
Plant Sciences
Natalia de Matos Balsalobre, Elisangela Dos Santos, Sidney Mariano Dos Santos, Arielle Cristina Arena, Elisabete Castelon Konkiewitz, Edward Benjamin Ziff, Anelise Samara Nazari Formagio, Candida Aparecida Leite Kassuya
Summary: The aim of this study was to investigate the analgesic and anti-arthritic properties of EOAE and viridiflorol using in vivo models.
JOURNAL OF ETHNOPHARMACOLOGY
(2023)
Article
Pharmacology & Pharmacy
Jiyoon Yang, Su-Yeon Lee, Soo-Kyeong Jang, Ki-Joong Kim, Mi-Jin Park
Summary: This study investigated the anti-inflammatory effects of various citrus cultivars and their active anti-inflammatory components. The essential oils from Citrus japonica and Citrus maxima exhibited superior anti-inflammatory activities, and α-terpineol was identified as an active anti-inflammatory compound.
Review
Biochemistry & Molecular Biology
Fatima Faheem, Zhi Wei Liu, Roshina Rabail, Iahtisham-Ul Haq, Maryam Gul, Marcin Bryla, Marek Roszko, Marek Kieliszek, Ahmad Din, Rana Muhammad Aadil
Summary: This article explores the role of lemongrass and its essential oil in food preservation. Lemongrass has significant antimicrobial and antioxidant activity, making it a natural preservative that can replace synthetic preservatives.
Article
Environmental Sciences
Shilpa Purkait, Abhishek Bhattacharya, Anwesa Bag, Rabi Ranjan Chattopadhyay
Summary: The study demonstrated that a combination of cinnamaldehyde and eugenol exhibited synergistic antimicrobial activity against foodborne microbes and antioxidant efficacy, without cytotoxic effects on human cells. This suggests that the cinnamaldehyde/eugenol blend could be a potential novel antimicrobial and antioxidant agent in food and pharmaceutical industries.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Plant Sciences
Bruno Oliveira de Veras, Joao Ricardhis Saturnino de Oliveira, Vera Lucia de Menezes Lima, Daniela Maria do Amaral Ferraz Navarro, Julio Cesar Ribeiro de Oliveira Farias de Aguiar, Geovanna Maria de Medeiros Moura, Jose Wellinton da Silva, Caio Rodrigo Dias de Assis, Krystyna Gorlach-Lira, Priscilla Anne Castro de Assis, Jorge Irapuan de Souza Barbosa, Maria Rita Cabral Sales de Melo, Maria Betania Melo de Oliveira, Marcia Vanusa da Silva, Ana Catarina de Souza Lopes
Summary: This study investigated the chemical composition and various activities of the essential oil from Verbesina macrophylla, including antimicrobial, anti-inflammatory, and antipyretic properties. The essential oil showed low hemolytic activity on human red blood cells and demonstrated safety in acute toxicity testing in animals. The results suggest potential industrial value in developing drugs with natural antimicrobial, anti-inflammatory, and antipyretic effects from V. macrophylla.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Article
Food Science & Technology
Ramandeep Kaur, Lovedeep Kaur, Tanushree B. Gupta, John Bronlund
Summary: This research finds that manuka and kanuka oils have antimicrobial properties and can potentially be used as natural preservatives for food. Manuka oil shows a better antimicrobial effect against Listeria monocytogenes and Staphylococcus aureus compared to kanuka oil and rosemary oil. Furthermore, manuka oil demonstrates excellent antimicrobial activity in vacuum-packed beef pastes, suggesting it as a potential replacement for synthetic preservatives.
Review
Pharmacology & Pharmacy
Rocio Rivera Rodriguez, Jeremy James Johnson
Summary: Inflammatory Bowel Disease (IBD) is a chronic autoimmune disease characterized by intestinal inflammation. The incidence of IBD is rapidly increasing in newly developed countries, making it a global concern. Two major types of IBD, ulcerative colitis (UC) and Crohn's disease (CD), have different manifestations and locations of inflammation in the digestive tract. Current FDA-approved treatments for IBD are only effective for 50% of patients and come with serious side effects, highlighting the need for safer and more effective therapies. Plant-based diets, such as the Mediterranean diet rich in anti-inflammatory phytochemicals, have shown benefits in preventing and improving symptoms of IBD. Terpenes, a class of phytochemicals abundant in Mediterranean herbs and citrus fruits, have been studied for their potential to modulate inflammatory signaling in IBD. However, there is still conflicting and inconclusive evidence regarding their effectiveness. This review evaluates preclinical studies on terpenes and their impact on basic inflammatory signaling in IBD.
PHARMACOLOGY & THERAPEUTICS
(2023)
Review
Food Science & Technology
Mingyue Jiao, Chao Liu, M. A. Prieto, Xiaoming Lu, Wenfu Wu, Jinyue Sun, P. Garcia-Oliveira, Xiaozhen Tang, Jianbo Xiao, Jesus Simal-Gandara, Dagang Hu, Ningyang Li
Summary: Papaya is an important fruit tree cultivated worldwide, and its edible part has high nutritional and sensory value. Papaya by-products contain bioactive compounds with diverse biological properties, which have potential applications in pharmaceutical, food, and cosmetic industries.
FOOD REVIEWS INTERNATIONAL
(2023)
Review
Food Science & Technology
Xuhan Yang, Zhonglu Niu, Xiaorui Wang, Xiaoming Lu, Jinyue Sun, M. Carpena, M. A. Prieto, Jesus Simal-Gandara, Jianbo Xiao, Chao Liu, Ningyang Li
Summary: Pomegranate is a delicious fruit with beautiful flowers, rich in bioactive compounds that have benefits for human health. Different parts of the pomegranate contain distinct bioactive components, which possess antioxidant, anti-inflammatory, and anti-cancer properties, among others. It is widely used in various fields such as food, health care, and medicine.
FOOD REVIEWS INTERNATIONAL
(2023)
Review
Medicine, Research & Experimental
Sunday Amos Onikanni, Bashir Lawal, Babatunji Emmanuel Oyinloye, Basiru Olaitan Ajiboye, Sukhbat Ulziijargal, Chih-Hao Wang, Talha Bin Emran, Jesus Simal-Gandara
Summary: Mitochondria malfunction is associated with beta-cell failure and various neurodegenerative disorders. Understanding the role of mitochondria in beta-cell dysfunction and neurodegenerative disorders could lead to better approaches for addressing these health issues.
Review
Immunology
Gaber El-Saber Batiha, Hayder M. Al-kuraishy, Ali Al-Gareeb, Mubarak Alruwaili, Raed AlRuwaili, Sarah M. Albogami, Mohammed Alorabi, Hebatallah M. Saad, Jesus Simal-Gandara
Summary: Neuroinflammation can occur during the Covid-19 era due to the neuronal effects of the SARS-CoV-2 virus and associated immune activation. Therapeutic options such as glibenclamide may help alleviate Covid-19-induced neuroinflammation by reducing inflammation and protecting against brain injury.
INFLAMMOPHARMACOLOGY
(2023)
Review
Medicine, General & Internal
Neil Patel, Yashendra Sethi, Nirja Kaka, Oroshay Kaiwan, Ishita Gupta, Rahma Sameh Shaheen, Shady Sapoor, Hitesh Chopra, Mihaela Simona Popoviciu, Talha Bin Emran, Simona Cavalu
Summary: Acute hepatitis is a growing concern with recent outbreaks affecting pediatric populations in around 35 countries, including developed nations. The outbreaks have been associated with devastating liver failure in approximately 10% of affected patients. Clinical presentation resembles typical acute hepatitis symptoms, but tests have come back negative for known hepatitis viruses, leading to the term non-HepA-E hepatitis. Adenovirus and SARS-CoV-2 have been identified as potential causes. International efforts are underway to establish diagnostic and management protocols to control these outbreaks. This comprehensive review aims to provide evidence-based conclusions to assist clinicians.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Immunology
Manish Dhawan, Ali A. Rabaan, Mahmoud M. Al Fawarah, Souad A. Almuthree, Roua A. Alsubki, Amal H. Alfaraj, Mutaib M. Mashraqi, Saleh A. Alshamrani, Wesam A. Abduljabbar, Ameen S. S. Alwashmi, Fatimah Al Ibrahim, Abdulmonem A. Alsaleh, Faryal Khamis, Jameela Alsalman, Manish Sharma, Talha Bin Emran
Summary: The emergence of novel variants of SARS-CoV-2 and their ability to evade the immune response makes it essential to understand the mechanisms of interaction between the virus and the human immune system. This understanding is crucial for the development of effective vaccines against COVID-19. T cells play a critical role in reducing viral load and containing the infection, but their hyperactivation and reduced numbers are associated with severe disease. The involvement of T cells in determining the prognosis of SARS-CoV-2 infection and the strategies to enhance T cell-mediated immune responses are still not fully understood.
Review
Food Science & Technology
Mohamad Fawzi Mahomoodally, Shahana Khatoon Khadaroo, Muzzammil Hosenally, Gokhan Zengin, Maksim Rebezov, Mohammad Ali Shariati, Asaad Khalid, Ashraf N. Abdalla, Alanood S. Algarni, Jesus Simal-Gandara
Summary: This review systematically summarizes the traditional uses, nutritional value, phytochemical profile, medicinal properties, and potential as a functional food of different parts of the date palm tree. The study found that date seeds are effective against E. coli and Staphylococcus aureus, date pollen can manage hormonal problems and boost fertility, and palm leaves have anti-hyperglycemic effects. However, there is a lack of clinical validation studies on the medicinal uses of date fruit and other plant parts.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Letter
Surgery
AbdulRahman A. Saied, Deepak Chandran, Hitesh Chopra, Abhijit Dey, Talha B. Emran, Kuldeep Dhama
INTERNATIONAL JOURNAL OF SURGERY
(2023)
Article
Chemistry, Multidisciplinary
Yahaya Saadu Itas, Abdussalam Balarabe Suleiman, Chifu E. Ndikilar, Abdullahi Lawal, Razif Razali, Ismail Ibrahim Idowu, Mayeen Uddin Khandaker, Amina Muhammad Danmadami, Pervaiz Ahmad, Talha Bin Emran, Mohammad Rashed Iqbal Faruque
Summary: In this study, the structural, electronic, and optical properties of a combined system of carbon and boron nitride nanotubes were investigated. The results showed that the double-walled carbon boron nitride nanotube (DWCBNNT) systems exhibited high stability under different interwall distances. The electronic properties of DWCBNNTs revealed semiconducting behavior, and the optical properties demonstrated refractive capabilities in all directions, which make them suitable for use in magnifying glass materials.
JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Medicinal
Trina Ekawati Tallei, Fatimawali, Ahmad Akroman Adam, Dewi Ekatanti, Ismail Celik, Rizka Fatriani, Firzan Nainu, Wisnu Ananta Kusuma, Ali A. Rabaan, Rinaldi Idroes
Summary: This study used multimodal computational studies to uncover the anti-inflammatory properties of fermented pineapple juice. Several compounds were identified that showed potential as anti-inflammatory agents, and molecular docking and dynamics simulations confirmed stable interactions with their respective receptors. These findings provide valuable insights for further experimental validation and development of these compounds as anti-inflammatory agents.
ARCHIV DER PHARMAZIE
(2023)
Article
Chemistry, Medicinal
Mahema Sivakumar, Sheikh F. Ahmad, Talha Bin Emran, Paola Isabel Angulo-Bejarano, Ashutosh Sharma, Shiek S. S. J. Ahmed
Summary: This study identifies a potential therapeutic target for radioresistant breast cancer through protein network analysis and evaluates a phytochemical compound from brown algae as a promising candidate.
Article
Chemistry, Medicinal
Catarina Lourenco-Lopes, Aurora Silva, Paula Garcia-Oliveira, Anton Soria-Lopez, Javier Echave, Clara Grosso, Lucia Cassani, Maria Fatima Barroso, Jesus Simal-Gandara, Maria Fraga-Corral, Miguel A. Prieto
Summary: This study investigated the kinetic behavior of Fucoxanthin (Fx) and optimized the time, temperature, and ethanol concentration variables for the best Fx yield from Undaria pinnatifida using conventional heat extraction. The content, extraction yield, and purity of Fx were determined and the optimal conditions for each were identified. The results provide valuable information for potential applications in various industries and can help reduce energy and solvent consumption while maximizing extraction yields.
Article
Environmental Sciences
Lin Li, Bei Fan, Zhiqiang Kong, Yifan Zhang, Mengying Zhao, Jesus Simal-Gandara, Fengzhong Wang, Minmin Li
Summary: This study investigated the reproductive toxicity of CBD on adult zebrafish. The results showed that CBD treatment led to a decrease in spawning, higher natural mortality, and malformation rates in female zebrafish. Both male and female zebrafish experienced changes in gonadosomatic index, content of vitellogenin, and sex hormone synthesis genes. Apoptosis-related genes were upregulated in the brain, gonad, and liver of zebrafish. These findings suggest that CBD can damage reproductive function by inducing an apoptotic response and inhibiting zebrafish reproductive ability.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Review
Integrative & Complementary Medicine
Md. Faysal, Jishan Khan, Mehrukh Zehravi, Nikhil Nath, Laliteshwar Pratap Singh, Saloni Kakkar, Rajashekar Perusomula, Pathan Amanulla Khan, Firzan Nainu, Mohammed Asiri, Sharuk L. Khan, Rajib Das, Talha Bin Emran, Polrat Wilairatana
Summary: Honokiol, a bioactive molecule derived from the Magnolia plant, has potential neuroprotective properties and could be used for the treatment of various neurological diseases. Furthermore, honokiol derivatives have also been identified as potential therapeutic options for these diseases.
Meeting Abstract
Clinical Neurology
J. Moura, C. Pinto, P. Freixo, C. Ramos, E. Silva, F. Nery, J. Gandara, V. Lopes, S. Ferreira, J. Presa, J. Castro Ferreira, H. Pessegueiro, M. Magalhaes
MOVEMENT DISORDERS
(2023)
