Brain-derived neurotrophic factor attenuates doxorubicin-induced cardiac dysfunction through activating Akt signalling in rats

Carvedilol Administration Can Prevent Doxorubicin-Induced Cardiotoxicity: A Double-Blind Randomized Trial

(2016) Ahmad Tashakori Beheshti et al.   CARDIOLOGY

BDNF protects pancreatic β cells (RIN5F) against cytotoxic action of alloxan, streptozotocin, doxorubicin and benzo(a)pyrene in vitro

(2016) Siresha Bathina et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The human amniotic fluid stem cell secretome effectively counteracts doxorubicin-induced cardiotoxicity

(2016) Edoardo Lazzarini et al.   Scientific Reports

Significance of Low Plasma Levels of Brain-Derived Neurotrophic Factor in Patients With Heart Failure

(2015) Seiji Takashio et al.   AMERICAN JOURNAL OF CARDIOLOGY

Insulin prevents bone morphogenetic protein-4 induced cardiomyocyte apoptosis through activating Akt

(2015) Yue Xing et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Modulation of Pulmonary Vascular Remodeling in Hypoxia: Role of 15-LOX-2/15-HETE-MAPKs Pathway

(2015) Xiufeng Yu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Macranthol promotes hippocampal neuronal proliferation in mice via BDNF–TrkB–PI3K/Akt signaling pathway

(2015) Liu Luo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Brain-Derived Neurotrophic Factor Regulates TRPC3/6 Channels and Protects Against Myocardial Infarction in Rodents

(2015) Pengzhou Hang et al.   International Journal of Biological Sciences

MiR-21 Protected Cardiomyocytes against Doxorubicin-Induced Apoptosis by Targeting BTG2

(2015) Zhongyi Tong et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Serum Brain-Derived Neurotropic Factor Level Predicts Adverse Clinical Outcomes in Patients With Heart Failure

(2015) Arata Fukushima et al.   JOURNAL OF CARDIAC FAILURE

BDNF modulates heart contraction force and long-term homeostasis through truncated TrkB.T1 receptor activation

(2015) Gianluca Fulgenzi et al.   JOURNAL OF CELL BIOLOGY

Resveratrol, a polyphenol phytoalexin, protects against doxorubicin-induced cardiotoxicity

(2015) Jun Gu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Combined Ampakine and BDNF Treatments Enhance Poststroke Functional Recovery in Aged Mice via AKT-CREB Signaling

(2015) Andrew N Clarkson et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Constitutive BDNF/TrkB signaling is required for normal cardiac contraction and relaxation

(2015) Ning Feng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Potent Paracrine Effects of human induced Pluripotent Stem Cell-derived Mesenchymal Stem Cells Attenuate Doxorubicin-induced Cardiomyopathy

(2015) Yuelin Zhang et al.   Scientific Reports

Ghrelin inhibits doxorubicin cardiotoxicity by inhibiting excessive autophagy through AMPK and p38-MAPK

(2014) Xue Wang et al.   BIOCHEMICAL PHARMACOLOGY

BDNF Mediates Neuroprotection against Oxygen-Glucose Deprivation by the Cardiac Glycoside Oleandrin

(2014) Michael J. Van Kanegan et al.   JOURNAL OF NEUROSCIENCE

Prevention of Anthracycline-Induced Cardiotoxicity

(2014) Pimprapa Vejpongsa et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Manipulation of Cardiac Phosphatidylinositol 3-Kinase (PI3K)/Akt Signaling by Apoptosis Regulator through Modulating IAP Expression (ARIA) Regulates Cardiomyocyte Death during Doxorubicin-induced Cardiomyopathy

(2013) Youhei Kitamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Brain-Derived Neurotrophic Factor Protects Against Cardiac Dysfunction After Myocardial Infarction via a Central Nervous System–Mediated Pathway

(2012) Sho Okada et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Doxorubicin-induced cardiomyopathy: From molecular mechanisms to therapeutic strategies

(2012) Yanti Octavia et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Identification of the molecular basis of doxorubicin-induced cardiotoxicity

(2012) Sui Zhang et al.   NATURE MEDICINE

Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in mice through SIRT1-mediated deacetylation of p53

(2011) C. Zhang et al.   CARDIOVASCULAR RESEARCH

Mechanisms and management of doxorubicin cardiotoxicity

(2011) Y. Shi et al.   HERZ

Cardioprotective effect of metoprolol and enalapril in doxorubicin-treated lymphoma patients: A prospective, parallel-group, randomized, controlled study with 36-month follow-up

(2010) Peter Georgakopoulos et al.   AMERICAN JOURNAL OF HEMATOLOGY

Pretreatment with angiotensin-converting enzyme inhibitor improves doxorubicin-induced cardiomyopathy via preservation of mitochondrial function

(2010) Asimina Hiona et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Targeted Therapy for Advanced Prostate Cancer: Inhibition of the PI3K/Akt/mTOR Pathway

(2009) Todd Morgan et al.   CURRENT CANCER DRUG TARGETS

Fluvoxamine and sigma-1 receptor agonists dehydroepiandrosterone (DHEA)-sulfate induces the Ser473-phosphorylation of Akt-1 in PC12 cells

(2009) Miho Nakano et al.   LIFE SCIENCES

Heat Shock Protein 20 Interacting With Phosphorylated Akt Reduces Doxorubicin-Triggered Oxidative Stress and Cardiotoxicity

(2008) Guo-Chang Fan et al.   CIRCULATION RESEARCH

MAPK signalling in cardiovascular health and disease: molecular mechanisms and therapeutic targets

(2008) Anthony J. Muslin   CLINICAL SCIENCE