PP1 initiates the dephosphorylation of MASTL, triggering mitotic exit and bistability in human cells

Protein phosphatase 1 is essential for Greatwall inactivation at mitotic exit

(2015) A. Heim et al.   EMBO REPORTS

Rapid Additive-Free Selenocystine–Selenoester Peptide Ligation

(2015) Nicholas J. Mitchell et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Global Phosphoproteomic Mapping of Early Mitotic Exit in Human Cells Identifies Novel Substrate Dephosphorylation Motifs

(2015) Rachael A. McCloy et al.   MOLECULAR & CELLULAR PROTEOMICS

Cyclin E2 is the predominant E-cyclin associated with NPAT in breast cancer cells

(2015) Samuel Rogers et al.   Cell Division

Greatwall promotes cell transformation by hyperactivating AKT in human malignancies

(2015) Jorge Vera et al.   eLife

Regulation of Greatwall kinase by protein stabilization and nuclear localization

(2014) Tomomi M Yamamoto et al.   CELL CYCLE

Partial inhibition of Cdk1 in G2phase overrides the SAC and decouples mitotic events

(2014) Rachael A McCloy et al.   CELL CYCLE

Dependency of the Spindle Assembly Checkpoint on Cdk1 Renders the Anaphase Transition Irreversible

(2014) Ahmed Rattani et al.   CURRENT BIOLOGY

A PP1–PP2A phosphatase relay controls mitotic progression

(2014) Agnes Grallert et al.   NATURE

PP2A/B55 and Fcp1 Regulate Greatwall and Ensa Dephosphorylation during Mitotic Exit

(2014) Nadia Hégarat et al.   PLoS Genetics

Greatwall-phosphorylated Endosulfine is both an inhibitor and a substrate of PP2A-B55 heterotrimers

(2014) Byron C Williams et al.   eLife

Chemical Activators of Protein Phosphatase-1 Induce Calcium Release inside Intact Cells

(2013) Gregor Reither et al.   CHEMISTRY & BIOLOGY

Global characterization of signalling networks associated with tamoxifen resistance in breast cancer

(2013) Brigid C. Browne et al.   FEBS Journal

The BEG (PP2A-B55/ENSA/Greatwall) Pathway Ensures Cytokinesis follows Chromosome Separation

(2013) Michael J. Cundell et al.   MOLECULAR CELL

The Cdk1–APC/C cell cycle oscillator circuit functions as a time-delayed, ultrasensitive switch

(2013) Qiong Yang et al.   NATURE CELL BIOLOGY

Rif1 Prevents Resection of DNA Breaks and Promotes Immunoglobulin Class Switching

(2013) M. Di Virgilio et al.   SCIENCE

Molecular mechanisms creating bistable switches at cell cycle transitions

(2013) A. Verdugo et al.   Open Biology

Development of a Peptide that Selectively Activates Protein Phosphatase-1 in Living Cells

(2012) Jayanta Chatterjee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Determinants for Activation of the Atypical AGC Kinase Greatwall during M Phase Entry

(2012) K. A. Blake-Hodek et al.   MOLECULAR AND CELLULAR BIOLOGY

Quantitative Live Imaging of Endogenous DNA Replication in Mammalian Cells

(2012) Andrew Burgess et al.   PLoS One

A Quantitative Model for Ordered Cdk Substrate Dephosphorylation during Mitotic Exit

(2011) Céline Bouchoux et al.   CELL

PP1/Repo-Man Dephosphorylates Mitotic Histone H3 at T3 and Regulates Chromosomal Aurora B Targeting

(2011) Junbin Qian et al.   CURRENT BIOLOGY

Characterization of the Mechanisms Controlling Greatwall Activity

(2011) S. Vigneron et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulation of Greatwall kinase during Xenopus oocyte maturation

(2011) Tomomi M. Yamamoto et al.   MOLECULAR BIOLOGY OF THE CELL

MOPED: Model Organism Protein Expression Database

(2011) Eugene Kolker et al.   NUCLEIC ACIDS RESEARCH

Boosting and suppressing mitotic phosphorylation

(2011) René H. Medema et al.   TRENDS IN BIOCHEMICAL SCIENCES

Progressive Activation of CyclinB1-Cdk1 Coordinates Entry to Mitosis

(2010) Olivier Gavet et al.   DEVELOPMENTAL CELL

Cdc14: a highly conserved family of phosphatases with non-conserved functions?

(2010) A. Mocciaro et al.   JOURNAL OF CELL SCIENCE

Live-cell imaging RNAi screen identifies PP2A–B55α and importin-β1 as key mitotic exit regulators in human cells

(2010) Michael H. A. Schmitz et al.   NATURE CELL BIOLOGY

Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance

(2010) Andrew Burgess et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Substrate of Greatwall Kinase, Arpp19, Controls Mitosis by Inhibiting Protein Phosphatase 2A

(2010) A. Gharbi-Ayachi et al.   SCIENCE

Greatwall Phosphorylates an Inhibitor of Protein Phosphatase 2A That Is Essential for Mitosis

(2010) S. Mochida et al.   SCIENCE

Greatwall maintains mitosis through regulation of PP2A

(2009) Suzanne Vigneron et al.   EMBO JOURNAL

Regulated activity of PP2A–B55δ is crucial for controlling entry into and exit from mitosis in Xenopus egg extracts

(2009) Satoru Mochida et al.   EMBO JOURNAL

The decision to enter mitosis: feedback and redundancy in the mitotic entry network

(2009) Arne Lindqvist et al.   JOURNAL OF CELL BIOLOGY

Irreversibility of mitotic exit is the consequence of systems-level feedback

(2009) Sandra López-Avilés et al.   NATURE

Unlimited multistability in multisite phosphorylation systems

(2009) Matthew Thomson et al.   NATURE

PP1-mediated dephosphorylation of phosphoproteins at mitotic exit is controlled by inhibitor-1 and PP1 phosphorylation

(2009) Judy Qiju Wu et al.   NATURE CELL BIOLOGY

Dynamical modeling and multi-experiment fitting with PottersWheel

(2008) Thomas Maiwald et al.   BIOINFORMATICS