Dynamic Interleukin-1 Receptor Type 1 Signaling Mediates Microglia-Vasculature Interactions Following Repeated Systemic LPS

Interleukin-1 receptor on hippocampal neurons drives social withdrawal and cognitive deficits after chronic social stress

(2020) Damon J. DiSabato et al.   MOLECULAR PSYCHIATRY

Gasdermin-D-dependent IL-1α release from microglia promotes protective immunity during chronic Toxoplasma gondii infection

(2020) Samantha J. Batista et al.   Nature Communications

Alzheimer’s Patient Microglia Exhibit Enhanced Aging and Unique Transcriptional Activation

(2020) Karpagam Srinivasan et al.   Cell Reports

Serial systemic injections of endotoxin (LPS) elicit neuroprotective spinal cord microglia through IL-1-dependent cross-talk with endothelial cells

(2020) Camila M. Freria et al.   JOURNAL OF NEUROSCIENCE

Cell-Type-Specific Interleukin 1 Receptor 1 Signaling in the Brain Regulates Distinct Neuroimmune Activities

(2019) Xiaoyu Liu et al.   IMMUNITY

Priming Microglia for Innate Immune Memory in the Brain

(2019) Jonas J. Neher et al.   TRENDS IN IMMUNOLOGY

Interleukin-1 causes CNS inflammatory cytokine expression via endothelia-microglia bi-cellular signaling

(2019) Ling Zhu et al.   BRAIN BEHAVIOR AND IMMUNITY

Dual microglia effects on blood brain barrier permeability induced by systemic inflammation

(2019) Koichiro Haruwaka et al.   Nature Communications

Acute transient cognitive dysfunction and acute brain injury induced by systemic inflammation occur by dissociable IL-1-dependent mechanisms

(2018) Donal T. Skelly et al.   MOLECULAR PSYCHIATRY

Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer’s Disease Not Evident in Mouse Models

(2018) Brad A. Friedman et al.   Cell Reports

Brain Lipopolysaccharide Preconditioning-Induced Gene Reprogramming Mediates a Tolerance State in Electroconvulsive Shock Model of Epilepsy

(2018) Elham Amini et al.   Frontiers in Pharmacology

Dexmedetomidine Prevents Lipopolysaccharide-Induced MicroRNA Expression in the Adult Rat Brain

(2017) Nadine Paeschke et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Amplification and propagation of interleukin-1β signaling by murine brain endothelial and glial cells

(2017) Stephanie M. Krasnow et al.   Journal of Neuroinflammation

Sympathetic Release of Splenic Monocytes Promotes Recurring Anxiety Following Repeated Social Defeat

(2016) Daniel B. McKim et al.   BIOLOGICAL PSYCHIATRY

Lipopolysaccharide Preconditioning Induces an Anti-inflammatory Phenotype in BV2 Microglia

(2016) Yongwei Qin et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Neuroinflammatory Dynamics Underlie Memory Impairments after Repeated Social Defeat

(2016) Daniel B. McKim et al.   JOURNAL OF NEUROSCIENCE

Long-lasting pro-inflammatory suppression of microglia by LPS-preconditioning is mediated by RelB-dependent epigenetic silencing

(2015) W. Schaafsma et al.   BRAIN BEHAVIOR AND IMMUNITY

Sequential activation of microglia and astrocyte cytokine expression precedes increased iba-1 or GFAP immunoreactivity following systemic immune challenge

(2015) Diana M. Norden et al.   GLIA

Lipopolysaccharide-induced blood-brain barrier disruption: roles of cyclooxygenase, oxidative stress, neuroinflammation, and elements of the neurovascular unit

(2015) William A. Banks et al.   Journal of Neuroinflammation

Interleukin 1 Type 1 Receptor Restore: A Genetic Mouse Model for Studying Interleukin 1 Receptor-Mediated Effects in Specific Cell Types

(2015) X. Liu et al.   JOURNAL OF NEUROSCIENCE

Lipopolysaccharide preconditioning facilitates M2 activation of resident microglia after spinal cord injury

(2014) Kentaro Hayakawa et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Species-Dependent Blood-Brain Barrier Disruption of Lipopolysaccharide: Amelioration by ColistinIn VitroandIn Vivo

(2013) Liang Jin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Interleukin-1 participates in the classical and alternative activation of microglia/macrophages after spinal cord injury

(2012) Atsushi Sato et al.   Journal of Neuroinflammation

Lipopolysaccharide-Induced Microglial Activation and Neuroprotection against Experimental Brain Injury Is Independent of Hematogenous TLR4

(2012) Z. Chen et al.   JOURNAL OF NEUROSCIENCE

Lipopolysaccharide-induced interleukin (IL)-4 receptor-α expression and corresponding sensitivity to the M2 promoting effects of IL-4 are impaired in microglia of aged mice

(2011) Ashley M. Fenn et al.   BRAIN BEHAVIOR AND IMMUNITY

LPS preconditioning redirects TLR signaling following stroke: TRIF-IRF3 plays a seminal role in mediating tolerance to ischemic injury

(2011) Keri B Vartanian et al.   Journal of Neuroinflammation

The Akt-Endothelial Nitric Oxide Synthase Pathway in Lipopolysaccharide Preconditioning-Induced Hypoxic-Ischemic Tolerance in the Neonatal Rat Brain

(2010) Hsiang-Yin Lin et al.   STROKE

Minimal penetration of lipopolysaccharide across the murine blood–brain barrier

(2009) William A. Banks et al.   BRAIN BEHAVIOR AND IMMUNITY

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE