CXCR4/CXCL12 Activities in the Tumor Microenvironment and Implications for Tumor Immunotherapy
出版年份 2022 全文链接
标题
CXCR4/CXCL12 Activities in the Tumor Microenvironment and Implications for Tumor Immunotherapy
作者
关键词
-
出版物
Cancers
Volume 14, Issue 9, Pages 2314
出版商
MDPI AG
发表日期
2022-05-07
DOI
10.3390/cancers14092314
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Single-Molecule, Super-Resolution, and Functional Analysis of G Protein-Coupled Receptor Behavior Within the T Cell Immunological Synapse
- (2021) James H. Felce et al. Frontiers in Cell and Developmental Biology
- CXCR4 engagement triggers CD47 internalization and antitumor immunization in a mouse model of mesothelioma
- (2021) Rosanna Mezzapelle et al. EMBO Molecular Medicine
- HMGB1 promotes CXCL12‐dependent egress of murine B cells from Peyer's patches in homeostasis
- (2021) Lorenzo Spagnuolo et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Functional anatomy of the full-length CXCR4-CXCL12 complex systematically dissected by quantitative model-guided mutagenesis
- (2020) Bryan S. Stephens et al. Science Signaling
- The Chemokine Receptor CXCR4 in Cell Proliferation and Tissue Regeneration
- (2020) Marco E. Bianchi et al. Frontiers in Immunology
- The Role of the CXCL12/CXCR4/CXCR7 Chemokine Axis in Cancer
- (2020) Yi Shi et al. Frontiers in Pharmacology
- Tumor-educated B cells selectively promote breast cancer lymph node metastasis by HSPA4-targeting IgG
- (2019) Yan Gu et al. NATURE MEDICINE
- CXCR4, but not CXCR3, drives CD8+ T-cell entry into and migration through the murine bone marrow
- (2019) Marieke Goedhart et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Atypical chemokine receptor 3 (ACKR3): a comprehensive overview of its expression and potential roles in the immune system.
- (2019) Joyce Koenen et al. MOLECULAR PHARMACOLOGY
- Diversity, Mechanisms, and Significance of Macrophage Plasticity
- (2019) Massimo Locati et al. Annual Review of Pathology-Mechanisms of Disease
- Kinetics of CXCL12 binding to atypical chemokine receptor 3 reveal a role for the receptor N terminus in chemokine binding
- (2019) Martin Gustavsson et al. Science Signaling
- Coexpression of CCR7 and CXCR4 During B Cell Development Controls CXCR4 Responsiveness and Bone Marrow Homing
- (2019) Saria Mcheik et al. Frontiers in Immunology
- Membrane lipid environment: Potential modulation of chemokine receptor function
- (2018) Marcus Thelen et al. CYTOKINE
- A guide to chemokines and their receptors
- (2018) Catherine E. Hughes et al. FEBS Journal
- The role of CXCL12 in tumor microenvironment
- (2018) Wenfang Meng et al. GENE
- Targeting the CXCL12/CXCR4 pathway and myeloid cells to improve radiation treatment of locally advanced cervical cancer
- (2018) Magali Lecavalier-Barsoum et al. INTERNATIONAL JOURNAL OF CANCER
- GRK2 mediates TCR-induced transactivation of CXCR4 and TCR-CXCR4 complex formation which drives PI3Kγ/PREX1 signaling and T cell cytokine secretion
- (2018) Brittney A Dinkel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Separating Actin-Dependent Chemokine Receptor Nanoclustering from Dimerization Indicates a Role for Clustering in CXCR4 Signaling and Function
- (2018) Laura Martínez-Muñoz et al. MOLECULAR CELL
- miR200-regulated CXCL12β promotes fibroblast heterogeneity and immunosuppression in ovarian cancers
- (2018) Anne-Marie Givel et al. Nature Communications
- Asymmetrical ligand-induced cross-regulation of chemokine (C-X-C motif) receptor 4 by α1-adrenergic receptors at the heteromeric receptor complex
- (2018) Xianlong Gao et al. Scientific Reports
- Targeting the MIF/CXCR7/AKT Signaling Pathway in Castration-resistant Prostate Cancer
- (2018) Li Jia et al. MOLECULAR CANCER RESEARCH
- Chemokine Heterocomplexes and Cancer: A Novel Chapter to Be Written in Tumor Immunity
- (2018) Gianluca D'Agostino et al. Frontiers in Immunology
- Roles of the immune system in cancer: from tumor initiation to metastatic progression
- (2018) Hugo Gonzalez et al. GENES & DEVELOPMENT
- CD47 Blockade by Hu5F9-G4 and Rituximab in Non-Hodgkin’s Lymphoma
- (2018) Ranjana Advani et al. NEW ENGLAND JOURNAL OF MEDICINE
- Interaction of Zap70 and CXCR4 receptor at lamellipodia that determines the directionality during Jurkat T cells chemotaxis
- (2017) Chia-Yun Wu et al. MOLECULAR IMMUNOLOGY
- CXCR4 signaling and function require the expression of the IgD-class B-cell antigen receptor
- (2017) Martin Becker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HMGB1 targeting by ethyl pyruvate suppresses malignant phenotype of human mesothelioma
- (2017) Laura Pellegrini et al. Oncotarget
- CXCR4+FOXP3+CD25+ Lymphocytes Accumulate in CXCL12-Expressing Malignant Pleural Mesothelioma
- (2017) Y. Shimtzu et al. INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY
- Recruitment of mesenchymal stem cells and macrophages by dual release of stromal cell-derived factor-1 and a macrophage recruitment agent enhances wound closure
- (2016) Yang-Hee Kim et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Human Mesenchymal stem cells program macrophage plasticity by altering their metabolic status via a PGE2-dependent mechanism
- (2016) Anoop Babu Vasandan et al. Scientific Reports
- Induction of Regulatory B-Cells by Mesenchymal Stem Cells is Affected by SDF-1α-CXCR7
- (2015) Yan Qin et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Differentiation and maintenance of long-lived plasma cells
- (2015) Kohei Kometani et al. CURRENT OPINION IN IMMUNOLOGY
- CXCL12 Regulates through JAK1 and JAK2 Formation of Productive Immunological Synapses
- (2015) Graciela Cascio et al. JOURNAL OF IMMUNOLOGY
- CXCL12/CXCR4: a symbiotic bridge linking cancer cells and their stromal neighbors in oncogenic communication networks
- (2015) F Guo et al. ONCOGENE
- The HIV-1 Gp120/CXCR4 Axis Promotes CCR7 Ligand-Dependent CD4 T Cell Migration: CCR7 Homo- and CCR7/CXCR4 Hetero-Oligomer Formation as a Possible Mechanism for Up-Regulation of Functional CCR7
- (2015) Haruko Hayasaka et al. PLoS One
- Heteromerization of chemokine (C-X-C motif) receptor 4 with α1A/B-adrenergic receptors controls α1-adrenergic receptor function
- (2015) Abhishek Tripathi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Diversity and Inter-Connections in the CXCR4 Chemokine Receptor/Ligand Family: Molecular Perspectives
- (2015) Lukas Pawig et al. Frontiers in Immunology
- New nomenclature for atypical chemokine receptors
- (2014) Françoise Bachelerie et al. NATURE IMMUNOLOGY
- Biased ligands at G-protein-coupled receptors: promise and progress
- (2014) Jonathan D. Violin et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- M1 and M2: there is no “good” and “bad”—How macrophages promote malignancy-associated features in tumorigenesis
- (2014) Ole Helm et al. OncoImmunology
- Atypical chemokine receptors: from silence to sound
- (2013) Cinzia Cancellieri et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Regulatory T cells, interleukin (IL)-6, IL-8, Vascular endothelial growth factor (VEGF), CXCL10, CXCL11, epidermal growth factor (EGF) and hepatocyte growth factor (HGF) as surrogate markers of host immunity in patients with renal cell carcinoma
- (2013) Marianeve Polimeno et al. BJU INTERNATIONAL
- Radiation Therapy-Induced Tumor Invasiveness Is Associated with SDF-1-Regulated Macrophage Mobilization and Vasculogenesis
- (2013) Shu-Chi Wang et al. PLoS One
- Cancer Cell Secretion of the DAMP Protein HMGB1 Supports Progression in Malignant Mesothelioma
- (2012) S. Jube et al. CANCER RESEARCH
- Homeostatic and Tissue Reparation Defaults in Mice Carrying Selective Genetic Invalidation of CXCL12/Proteoglycan Interactions
- (2012) Patricia Rueda et al. CIRCULATION
- Systematic classification of vertebrate chemokines based on conserved synteny and evolutionary history
- (2012) Hisayuki Nomiyama et al. GENES TO CELLS
- Rapid Uptake and Degradation of CXCL12 Depend on CXCR7 Carboxyl-terminal Serine/Threonine Residues
- (2012) Frauke Hoffmann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4
- (2012) Milena Schiraldi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors
- (2012) S. B. Willingham et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Differential macrophage programming in the tumor microenvironment
- (2012) Brian Ruffell et al. TRENDS IN IMMUNOLOGY
- CXCR7 impact on CXCL12 biology and disease
- (2012) Lorena Sánchez-Martín et al. TRENDS IN MOLECULAR MEDICINE
- CXCL12/CXCR4 Blockade Induces Multimodal Antitumor Effects That Prolong Survival in an Immunocompetent Mouse Model of Ovarian Cancer
- (2011) E. Righi et al. CANCER RESEARCH
- CXCR7/CXCR4 Heterodimer Constitutively Recruits β-Arrestin to Enhance Cell Migration
- (2011) Fabien M. Décaillot et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Molecular control of endothelial cell behaviour during blood vessel morphogenesis
- (2011) Shane P. Herbert et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- CXCR4 and CXCR7 Have Distinct Functions in Regulating Interneuron Migration
- (2011) Yanling Wang et al. NEURON
- Hematopoietic stem and progenitor cell trafficking
- (2011) Irina B. Mazo et al. TRENDS IN IMMUNOLOGY
- CXCL12 (SDF-1)/CXCR4 Pathway in Cancer
- (2010) B. A. Teicher et al. CLINICAL CANCER RESEARCH
- Site-specific Phosphorylation of CXCR4 Is Dynamically Regulated by Multiple Kinases and Results in Differential Modulation of CXCR4 Signaling
- (2010) John M. Busillo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Thrombospondin-1 Inhibits VEGF Receptor-2 Signaling by Disrupting Its Association with CD47
- (2010) Sukhbir Kaur et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibitor of NF- B Kinases and Are Both Essential for High Mobility Group Box 1-Mediated Chemotaxis
- (2010) M. Penzo et al. JOURNAL OF IMMUNOLOGY
- CXCR7 Functions as a Scavenger for CXCL12 and CXCL11
- (2010) Ulrike Naumann et al. PLoS One
- CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling
- (2009) A. Levoye et al. BLOOD
- CXCR4 acts as a costimulator during thymic β-selection
- (2009) Paul C Trampont et al. NATURE IMMUNOLOGY
- -arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7
- (2009) S. Rajagopal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Control of Chemokine-Guided Cell Migration by Ligand Sequestration
- (2008) Bijan Boldajipour et al. CELL
- Ligand stabilization of CXCR4/δ-opioid receptor heterodimers reveals a mechanism for immune response regulation
- (2008) Oscar M. Pello et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Imaging chemokine receptor dimerization with firefly luciferase complementation
- (2008) Kathryn E. Luker et al. FASEB JOURNAL
- Bi-directional heterologous desensitization between the major HIV-1 co-receptor CXCR4 and the κ-opioid receptor
- (2008) Matthew J. Finley et al. JOURNAL OF NEUROIMMUNOLOGY
- Paired Receptor Specificity Explained by Structures of Signal Regulatory Proteins Alone and Complexed with CD47
- (2008) Deborah Hatherley et al. MOLECULAR CELL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started