Novel oxygen sensing mechanism in the spinal cord involved in cardiorespiratory responses to hypoxia

Calcium Imaging Analysis of Cellular Responses to Hypercapnia and Hypoxia in the NTS of Newborn Rat Brainstem Preparation

(2021) Hiroshi Onimaru et al.   Frontiers in Physiology

Acute O2 sensing through HIF2α-dependent expression of atypical cytochrome oxidase subunits in arterial chemoreceptors

(2020) Alejandro Moreno-Domínguez et al.   Science Signaling

O2-Dependent Protein Internalization Underlies Astrocytic Sensing of Acute Hypoxia by Restricting Multimodal TRPA1 Channel Responses

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On the presence and functional significance of sympathetic premotor neurons with collateralised spinal axons in the rat

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Physiology of the Carotid Body: From Molecules to Disease

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Acute intermittent hypoxia with concurrent hypercapnia evokes P2X and TRPV1 receptor-dependent sensory long-term facilitation in naïve carotid bodies

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The role of hypoxia-inducible factors in carotid body (patho) physiology

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Advances in cellular and integrative control of oxygen homeostasis within the central nervous system

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Nitric Oxide Orchestrates a Power-Law Modulation of Sympathetic Firing Behaviors in Neonatal Rat Spinal Cords

(2018) Chun-Kuei Su et al.   Frontiers in Physiology

On the existence of a central respiratory oxygen sensor

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Release of ATP by pre-Bötzinger complex astrocytes contributes to the hypoxic ventilatory response via a Ca2+ -dependent P2Y1 receptor mechanism

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Acute oxygen sensing by the carotid body: a rattlebag of molecular mechanisms

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TRP channels in oxygen physiology: distinctive functional properties and roles of TRPA1 in O2 sensing

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An autocrine purinergic signaling controls astrocyte-induced neuronal excitation

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The emerging role of AMPK in the regulation of breathing and oxygen supply

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Human hypertension, sympathetic activity and the selfish brain

(2016) Emma C. Hart   EXPERIMENTAL PHYSIOLOGY

Heme oxygenase-1-dependent central cardiorespiratory adaptations to chronic intermittent hypoxia in mice

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Structural basis of TRPA1 inhibition by HC-030031 utilizing species-specific differences

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Long-lasting facilitation of respiratory rhythm by treatment with TRPA1 agonist, cinnamaldehyde

(2015) Mariho Tani et al.   JOURNAL OF NEUROPHYSIOLOGY

Functional Oxygen Sensitivity of Astrocytes

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Nox family NADPH oxidases: Molecular mechanisms of activation

(2014) Ralf P. Brandes et al.   FREE RADICAL BIOLOGY AND MEDICINE

Spinal nNOS regulates phrenic motor facilitation by a 5-HT2B receptor- and NADPH oxidase-dependent mechanism

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Lactate-mediated glia-neuronal signalling in the mammalian brain

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Flufenamic acid as an ion channel modulator

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Preinspiratory calcium rise in putative pre-Bötzinger complex astrocytes

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Nitric oxide synthases: regulation and function

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Anandamide modulates carotid sinus nerve afferent activity via TRPV1 receptors increasing responses to heat

(2011) Arijit Roy et al.   JOURNAL OF APPLIED PHYSIOLOGY

NADPH oxidase-dependent and -independent mechanisms of reported inhibitors of reactive oxygen generation

(2011) Gregory J. Gatto et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

TRPA1 underlies a sensing mechanism for O2

(2011) Nobuaki Takahashi et al.   Nature Chemical Biology

Redox-Regulated Heterogeneous Thresholds for Ligand Recruitment among InsP3R Ca2+-Release Channels

(2010) Horia Vais et al.   BIOPHYSICAL JOURNAL

Astrocytes Control Breathing Through pH-Dependent Release of ATP

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High-frequency spinal cord stimulation of inspiratory muscles in dogs: a new method of inspiratory muscle pacing

(2009) Anthony F. DiMarco et al.   JOURNAL OF APPLIED PHYSIOLOGY

Variability in the occurrence of nitric oxide synthase immunoreactivity in different populations of rat sympathetic preganglionic neurons

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Role of H2O2-activated TRPM2 calcium channel in oxidant-induced endothelial injury

(2009) Claudie M. Hecquet et al.   THROMBOSIS AND HAEMOSTASIS

9-Phenanthrol inhibits human TRPM4 but not TRPM5 cationic channels

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Inhibition of the transient receptor potential cation channel TRPM2 by 2-aminoethoxydiphenyl borate (2-APB)

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Activation of transient receptor potential ankyrin 1 by hydrogen peroxide

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A negative interaction between brainstem and peripheral respiratory chemoreceptors modulates peripheral chemoreflex magnitude

(2008) Trevor A. Day et al.   JOURNAL OF PHYSIOLOGY-LONDON

Apocynin: Molecular Aptitudes

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Brain metabolism dictates the polarity of astrocyte control over arterioles

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