The Potential of the Gut Microbiome to Reshape the Cancer Therapy Paradigm

Cytotoxic Escherichia coli strains encoding colibactin, cytotoxic necrotizing factor, and cytolethal distending toxin colonize laboratory common marmosets (Callithrix jacchus)

(2021) Colleen S. McCoy et al.   Scientific Reports

Immunological design of commensal communities to treat intestinal infection and inflammation

(2021) Rebecca Louise Brown et al.   PLoS Pathogens

Lactobacillus rhamnosus GG induces cGAS/STING- dependent type I interferon and improves response to immune checkpoint blockade

(2021) Wei Si et al.   GUT

Targeting Glutamine Addiction in Gliomas

(2020) Marta Obara-Michlewska et al.   Cancers

Ketogenic Diets Alter the Gut Microbiome Resulting in Decreased Intestinal Th17 Cells

(2020) Qi Yan Ang et al.   CELL

Bioinorganic hybrid bacteriophage for modulation of intestinal microbiota to remodel tumor-immune microenvironment against colorectal cancer

(2020) Xue Dong et al.   Science Advances

Fusobacterium nucleatum confers chemoresistance by modulating autophagy in oesophageal squamous cell carcinoma

(2020) Yang Liu et al.   BRITISH JOURNAL OF CANCER

Gut microbiome directs hepatocytes to recruit MDSC and promote cholangiocarcinoma

(2020) Qianfei Zhang et al.   Cancer Discovery

Fusobacterium nucleatum Promotes the Development of Ulcerative Colitis by Inducing the Autophagic Cell Death of Intestinal Epithelial

(2020) Wenhao Su et al.   Frontiers in Cellular and Infection Microbiology

The effect of 16S rRNA region choice on bacterial community metabarcoding results

(2019) Yu. S. Bukin et al.   Scientific Data

The human gut bacterial genotoxin colibactin alkylates DNA

(2019) Matthew R. Wilson et al.   SCIENCE

Probiotic Bacteria: A Promising Tool in Cancer Prevention and Therapy

(2019) Agata Górska et al.   CURRENT MICROBIOLOGY

Provocative Question: Should Ketogenic Metabolic Therapy Become the Standard of Care for Glioblastoma?

(2019) Thomas N. Seyfried et al.   NEUROCHEMICAL RESEARCH

Exploring the emerging role of the microbiome in cancer immunotherapy

(2019) Jessica Fessler et al.   Journal for ImmunoTherapy of Cancer

Microbiota-Derived Short-Chain Fatty Acids Promote the Memory Potential of Antigen-Activated CD8+ T Cells

(2019) Annabell Bachem et al.   IMMUNITY

Gut Microbiota Shapes the Efficiency of Cancer Therapy

(2019) Weidong Ma et al.   Frontiers in Microbiology

The Microbiota-Gut-Brain Axis

(2019) John F. Cryan et al.   PHYSIOLOGICAL REVIEWS

Gut microbiota modulate dendritic cell antigen presentation and radiotherapy-induced antitumor immune response

(2019) Mireia Uribe-Herranz et al.   JOURNAL OF CLINICAL INVESTIGATION

Negative association of antibiotics on clinical activity of immune checkpoint inhibitors in patients with advanced renal cell and non-small-cell lung cancer

(2018) L Derosa et al.   ANNALS OF ONCOLOGY

Oral Polyphosphate Suppresses Bacterial Collagenase Production and Prevents Anastomotic Leak Due to Serratia marcescens and Pseudomonas aeruginosa

(2018) Sanjiv K. Hyoju et al.   ANNALS OF SURGERY

Mucus Microbiome of Anastomotic Tissue During Surgery Has Predictive Value for Colorectal Anastomotic Leakage

(2018) Jasper B. van Praagh et al.   ANNALS OF SURGERY

Gut microbiome–mediated bile acid metabolism regulates liver cancer via NKT cells

(2018) Chi Ma et al.   SCIENCE

The commensal microbiome is associated with anti–PD-1 efficacy in metastatic melanoma patients

(2018) Vyara Matson et al.   SCIENCE

Diet, Genetics, and the Gut Microbiome Drive Dynamic Changes in Plasma Metabolites

(2018) Shiho Fujisaka et al.   Cell Reports

The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer’s disease

(2018) Nicholas M. Vogt et al.   Alzheimers Research & Therapy

Biofilm Producing Salmonella Typhi: Chronic Colonization and Development of Gallbladder Cancer

(2017) Enea Gino Di Domenico et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Intestinal Microbiota and Relapse After Hematopoietic-Cell Transplantation

(2017) Jonathan U. Peled et al.   JOURNAL OF CLINICAL ONCOLOGY

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(2017)   MOVEMENT DISORDERS

Structure and function of Helicobacter pylori CagA, the first-identified bacterial protein involved in human cancer

(2017) Masanori HATAKEYAMA   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients

(2017) V. Gopalakrishnan et al.   SCIENCE

Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

(2017) Bertrand Routy et al.   SCIENCE

Metagenomic Shotgun Sequencing and Unbiased Metabolomic Profiling Identify Specific Human Gut Microbiota and Metabolites Associated with Immune Checkpoint Therapy Efficacy in Melanoma Patients

(2017) Arthur E. Frankel et al.   NEOPLASIA

Immunotherapy approaches in the treatment of malignant brain tumors

(2016) Anastasie M. Dunn-Pirio et al.   CANCER

Structural Change in Microbiota by a Probiotic Cocktail Enhances the Gut Barrier and Reduces Cancer via TLR2 Signaling in a Rat Model of Colon Cancer

(2016) Eugene Dogkotenge Kuugbee et al.   DIGESTIVE DISEASES AND SCIENCES

Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects

(2016) Romain Daillère et al.   IMMUNITY

Targeted Next Generation Sequencing Identifies Markers of Response to PD-1 Blockade

(2016) D. B. Johnson et al.   Cancer Immunology Research

Intestinal Blautia Is Associated with Reduced Death from Graft-versus-Host Disease

(2015) Robert R. Jenq et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Binding of the Fap2 Protein of Fusobacterium nucleatum to Human Inhibitory Receptor TIGIT Protects Tumors from Immune Cell Attack

(2015) Chamutal Gur et al.   IMMUNITY

The Microbiome, Intestinal Function, and Arginine Metabolism of Healthy Indian Women Are Different from Those of American and Jamaican Women

(2015) Christina C Kao et al.   JOURNAL OF NUTRITION

An environmentally benign antimicrobial nanoparticle based on a silver-infused lignin core

(2015) Alexander P. Richter et al.   Nature Nanotechnology

Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy

(2015) A. Sivan et al.   SCIENCE

The ecology of the microbiome: Networks, competition, and stability

(2015) K. Z. Coyte et al.   SCIENCE

Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

(2015) M. Vetizou et al.   SCIENCE

Systematic review: the role of the gut microbiota in chemotherapy- or radiation-induced gastrointestinal mucositis - current evidence and potential clinical applications

(2014) Y. Touchefeu et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

The effects of intestinal tract bacterial diversity on mortality following allogeneic hematopoietic stem cell transplantation

(2014) Y. Taur et al.   BLOOD

Self-reactive T cells: suppressing the suppressors

(2013) Jürgen C. Becker et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Helicobacter pylori-induced gastric inflammation and gastric cancer

(2013) Fei Wang et al.   CANCER LETTERS

Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment

(2013) Aleksandar D. Kostic et al.   Cell Host & Microbe

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

(2013) Shin Yoshimoto et al.   NATURE

The Intestinal Microbiota Modulates the Anticancer Immune Effects of Cyclophosphamide

(2013) S. Viaud et al.   SCIENCE

Immunotherapy for the Treatment of Glioblastoma

(2012) Alissa A. Thomas et al.   CANCER JOURNAL

Calpain Activation by the Shigella flexneri Effector VirA Regulates Key Steps in the Formation and Life of the Bacterium's Epithelial Niche

(2012) Jean Bergounioux et al.   Cell Host & Microbe

Irinotecan (CPT-11) Chemotherapy Alters Intestinal Microbiota in Tumour Bearing Rats

(2012) Xiaoxi B. Lin et al.   PLoS One

Spermine Oxidase Mediates the Gastric Cancer Risk Associated With Helicobacter pylori CagA

(2011) Rupesh Chaturvedi et al.   GASTROENTEROLOGY

Lactobacillus probiotic protects intestinal epithelium from radiation injury in a TLR-2/cyclo-oxygenase-2-dependent manner

(2011) Matthew A Ciorba et al.   GUT

Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis

(2011) A. C. Goodwin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial Enzyme

(2010) B. D. Wallace et al.   SCIENCE