Allosteric Regulation of IGF2BP1 as a Novel Strategy for the Activation of Tumor Immune Microenvironment
出版年份 2022 全文链接
标题
Allosteric Regulation of IGF2BP1 as a Novel Strategy for the Activation of Tumor Immune Microenvironment
作者
关键词
-
出版物
ACS Central Science
Volume -, Issue -, Pages -
出版商
American Chemical Society (ACS)
发表日期
2022-05-18
DOI
10.1021/acscentsci.2c00107
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The adaptive immune system is a major driver of selection for tumor suppressor gene inactivation
- (2021) Timothy D. Martin et al. SCIENCE
- Real-world data analyses unveiled the immune-related adverse effects of immune checkpoint inhibitors across cancer types
- (2021) Feicheng Wang et al. npj Precision Oncology
- Hematologic complications of immune checkpoint inhibitors
- (2021) Michael H Kroll et al. BLOOD
- MYC, MYCL, and MYCN as therapeutic targets in lung cancer
- (2020) Daniel Massó-Vallés et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Imp/IGF2BP levels modulate individual neural stem cell growth and division through myc mRNA stability
- (2020) Tamsin J Samuels et al. eLife
- Accelerating the Development of Personalized Cancer Immunotherapy by Integrating Molecular Patients’ Profiles with Dynamic Mathematical Models
- (2020) Zvia Agur et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Natural killer cells in cancer biology and therapy
- (2020) Song-Yang Wu et al. Molecular Cancer
- The oncofetal RNA-binding protein IGF2BP1 is a druggable, post-transcriptional super-enhancer of E2F-driven gene expression in cancer
- (2020) Simon Müller et al. NUCLEIC ACIDS RESEARCH
- Translation control of the immune checkpoint in cancer and its therapeutic targeting
- (2019) Yichen Xu et al. NATURE MEDICINE
- IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties
- (2019) Robert Dagil et al. NUCLEIC ACIDS RESEARCH
- Harnessing innate immunity in cancer therapy
- (2019) Olivier Demaria et al. NATURE
- Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) in cancer
- (2018) Xinwei Huang et al. Journal of Hematology & Oncology
- Targeting MYC in multiple myeloma
- (2018) K. K. Jovanović et al. LEUKEMIA
- Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation
- (2018) Huilin Huang et al. NATURE CELL BIOLOGY
- Cancer immunotherapy using checkpoint blockade
- (2018) Antoni Ribas et al. SCIENCE
- IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner
- (2018) Simon Müller et al. NUCLEIC ACIDS RESEARCH
- PD-L1 is commonly expressed and transcriptionally regulated by STAT3 and MYC in ALK-negative anaplastic large-cell lymphoma
- (2017) V Atsaves et al. LEUKEMIA
- A Novel IMP1 Inhibitor, BTYNB, Targets c-Myc and Inhibits Melanoma and Ovarian Cancer Cell Proliferation
- (2017) Lily Mahapatra et al. Translational Oncology
- Mechanism of β-actin mRNA Recognition by ZBP1
- (2017) Giuseppe Nicastro et al. Cell Reports
- Insulin-Like Growth Factor 2 - The Oncogene and its Accomplices
- (2016) Sonja Kessler et al. CURRENT PHARMACEUTICAL DESIGN
- Advances in identification and validation of protein targets of natural products without chemical modification
- (2016) J. Chang et al. NATURAL PRODUCT REPORTS
- MYC regulates the antitumor immune response through CD47 and PD-L1
- (2016) S. C. Casey et al. SCIENCE
- Covalent inhibitors in drug discovery: from accidental discoveries to avoided liabilities and designed therapies
- (2015) Renato A. Bauer DRUG DISCOVERY TODAY
- Two Isoforms of the RNA Binding Protein, Coding Region Determinant-binding Protein (CRD-BP/IGF2BP1), Are Expressed in Breast Epithelium and Support Clonogenic Growth of Breast Tumor Cells
- (2015) Saja A. Fakhraldeen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions
- (2015) Nian Liu et al. NATURE
- N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells
- (2014) Yang Wang et al. NATURE CELL BIOLOGY
- Subcellular localization and RNP formation of IGF2BPs (IGF2 mRNA-binding proteins) is modulated by distinct RNA-binding domains
- (2013) Kristin Wächter et al. BIOLOGICAL CHEMISTRY
- Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons
- (2012) Kate D. Meyer et al. CELL
- Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression?
- (2012) Jessica L. Bell et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
- (2012) Dan Dominissini et al. NATURE
- KH domains with impaired nucleic acid binding as a tool for functional analysis
- (2012) David Hollingworth et al. NUCLEIC ACIDS RESEARCH
- IMP-1 Displays Cross-Talk with K-Ras and Modulates Colon Cancer Cell Survival through the Novel Proapoptotic Protein CYFIP2
- (2011) P. S. Mongroo et al. CANCER RESEARCH
- Seven Transmembrane Receptors as Shapeshifting Proteins: The Impact of Allosteric Modulation and Functional Selectivity on New Drug Discovery
- (2010) T. Kenakin et al. PHARMACOLOGICAL REVIEWS
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started