标题
Combining selinexor with alisertib to target the p53 pathway in neuroblastoma
作者
关键词
Neuroblastoma, Pediatric oncology, Small molecule inhibitor, p53, Proteome, Phosphoproteome
出版物
NEOPLASIA
Volume 26, Issue -, Pages 100776
出版商
Elsevier BV
发表日期
2022-02-23
DOI
10.1016/j.neo.2022.100776
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Long-Term Follow-up of a Phase III Study of ch14.18 (Dinutuximab) + Cytokine Immunotherapy in Children with High-Risk Neuroblastoma: COG Study ANBL0032
- (2021) Alice L. Yu et al. CLINICAL CANCER RESEARCH
- XPO1 inhibition with selinexor synergizes with proteasome inhibition in neuroblastoma by targeting nuclear export of IkB
- (2021) Basia Galinski et al. Translational Oncology
- Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer’s Disease Progression
- (2020) Bing Bai et al. NEURON
- Irinotecan, Temozolomide, and Dinutuximab With GM-CSF in Children With Refractory or Relapsed Neuroblastoma: A Report From the Children’s Oncology Group
- (2020) Rajen Mody et al. JOURNAL OF CLINICAL ONCOLOGY
- Novel specialized cell state and spatial compartments within the germinal center
- (2020) Domenick E. Kennedy et al. NATURE IMMUNOLOGY
- Integrated analysis of ultra-deep proteomes in cortex, cerebrospinal fluid and serum reveals a mitochondrial signature in Alzheimer’s disease
- (2020) Hong Wang et al. Molecular Neurodegeneration
- Selinexor in patients with relapsed or refractory diffuse large B-cell lymphoma (SADAL): a single-arm, multinational, multicentre, open-label, phase 2 trial
- (2020) Nagesh Kalakonda et al. Lancet Haematology
- Subcellular distribution of p53 by the p53-responsive lncRNA NBAT1 determines chemotherapeutic response in neuroblastoma
- (2020) Sanhita Mitra et al. CANCER RESEARCH
- A Phase 2 Study of Alisertib in Children with Recurrent/Refractory Solid Tumors or Leukemia: Children's Oncology Group Phase 1 and Pilot Consortium ADVL0921)
- (2019) Yael P. Mosse et al. CLINICAL CANCER RESEARCH
- Deep undepleted human serum proteome profiling toward biomarker discovery for Alzheimer’s disease
- (2019) Kaushik Kumar Dey et al. Clinical Proteomics
- Oral Selinexor–Dexamethasone for Triple-Class Refractory Multiple Myeloma
- (2019) Ajai Chari et al. NEW ENGLAND JOURNAL OF MEDICINE
- Deep multiomics profiling of brain tumors identifies signaling networks downstream of cancer driver genes
- (2019) Hong Wang et al. Nature Communications
- Selective Inhibition of Nuclear Export With Oral Selinexor for Treatment of Relapsed or Refractory Multiple Myeloma
- (2018) Dan T. Vogl et al. JOURNAL OF CLINICAL ONCOLOGY
- Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses
- (2018) Elizabeth Stewart et al. CANCER CELL
- Irinotecan–temozolomide with temsirolimus or dinutuximab in children with refractory or relapsed neuroblastoma (COG ANBL1221): an open-label, randomised, phase 2 trial
- (2017) Rajen Mody et al. LANCET ONCOLOGY
- An update on the pharmacokinetics and pharmacodynamics of alisertib, a selective Aurora kinase A inhibitor
- (2016) Cameron T Durlacher et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Phase I Study of the Aurora A Kinase Inhibitor Alisertib in Combination With Irinotecan and Temozolomide for Patients With Relapsed or Refractory Neuroblastoma: A NANT (New Approaches to Neuroblastoma Therapy) Trial
- (2016) Steven G. DuBois et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase I Study of Selinexor, a Selective Inhibitor of Nuclear Export, in Combination With Fludarabine and Cytarabine, in Pediatric Relapsed or Refractory Acute Leukemia
- (2016) Thomas B. Alexander et al. JOURNAL OF CLINICAL ONCOLOGY
- First-in-Class, First-in-Human Phase I Study of Selinexor, a Selective Inhibitor of Nuclear Export, in Patients With Advanced Solid Tumors
- (2016) Albiruni R. Abdul Razak et al. JOURNAL OF CLINICAL ONCOLOGY
- JUMPg: An Integrative Proteogenomics Pipeline Identifying Unannotated Proteins in Human Brain and Cancer Cells
- (2016) Yuxin Li et al. JOURNAL OF PROTEOME RESEARCH
- Mass-spectrometric exploration of proteome structure and function
- (2016) Ruedi Aebersold et al. NATURE
- Aurora kinase A is required for hematopoiesis but is dispensable for murine megakaryocyte endomitosis and differentiation
- (2015) B. Goldenson et al. BLOOD
- Drugging MYCN through an Allosteric Transition in Aurora Kinase A
- (2014) William Clay Gustafson et al. CANCER CELL
- Systematic Optimization of Long Gradient Chromatography Mass Spectrometry for Deep Analysis of Brain Proteome
- (2014) Hong Wang et al. JOURNAL OF PROTEOME RESEARCH
- JUMP: A Tag-based Database Search Tool for Peptide Identification with High Sensitivity and Accuracy
- (2014) Xusheng Wang et al. MOLECULAR & CELLULAR PROTEOMICS
- Refined phosphopeptide enrichment by phosphate additive and the analysis of human brain phosphoproteome
- (2014) Haiyan Tan et al. PROTEOMICS
- Atomic basis of CRM1-cargo recognition, release and inhibition
- (2014) Ho Yee Joyce Fung et al. SEMINARS IN CANCER BIOLOGY
- Purged versus non-purged peripheral blood stem-cell transplantation for high-risk neuroblastoma (COG A3973): a randomised phase 3 trial
- (2013) Susan G Kreissman et al. LANCET ONCOLOGY
- Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma
- (2013) H Kocak et al. Cell Death & Disease
- NESdb: a database of NES-containing CRM1 cargoes
- (2012) Darui Xu et al. MOLECULAR BIOLOGY OF THE CELL
- Serine 312 phosphorylation is dispensable for wild-type p53 functions in vivo
- (2010) M K Lee et al. CELL DEATH AND DIFFERENTIATION
- High Frequency of p53/MDM2/p14ARF Pathway Abnormalities in Relapsed Neuroblastoma
- (2010) J. Carr-Wilkinson et al. CLINICAL CANCER RESEARCH
- Phosphorylation of Ser312 contributes to tumor suppression by p53 in vivo
- (2010) E. A. Slee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stabilization of N-Myc Is a Critical Function of Aurora A in Human Neuroblastoma
- (2009) Tobias Otto et al. CANCER CELL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now