Erythropoietin protects the inner blood–retinal barrier by inhibiting microglia phagocytosis via Src/Akt/cofilin signalling in experimental diabetic retinopathy

Erianin alleviates diabetic retinopathy by reducing retinal inflammation initiated by microglia cells via inhibiting hyperglycemia-mediated ERK1/2–NF-κB signaling pathway

(2019) Tianyu Zhang et al.   FASEB JOURNAL

Erythropoietin protects outer blood‐retinal barrier in experimental diabetic retinopathy by up‐regulating ZO‐1 and occludin

(2019) Chaoyang Zhang et al.   CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

The Role of Microglia in Diabetic Retinopathy: Inflammation, Microvasculature Defects and Neurodegeneration

(2018) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Quantifying Microglia Morphology from Photomicrographs of Immunohistochemistry Prepared Tissue Using ImageJ

(2018) Kimberly Young et al.   Jove-Journal of Visualized Experiments

Modulation of three key innate immune pathways for the most common retinal degenerative diseases

(2018) Isha Akhtar‐Schäfer et al.   EMBO Molecular Medicine

Picket-fences in the plasma membrane: functions in immune cells and phagocytosis

(2018) Sivakami M. Mylvaganam et al.   Seminars in Immunopathology

Microglia enhanced the angiogenesis, migration and proliferation of co-cultured RMECs

(2018) Xinyi Ding et al.   BMC Ophthalmology

Colony-stimulating factor 1 receptor inhibition prevents disruption of the blood-retina barrier during chronic inflammation

(2018) Despina Kokona et al.   Journal of Neuroinflammation

Fractalkine Signaling Attenuates Perivascular Clustering of Microglia and Fibrinogen Leakage during Systemic Inflammation in Mouse Models of Diabetic Retinopathy

(2017) Andrew S. Mendiola et al.   Frontiers in Cellular Neuroscience

Photo-enhancement of macrophage phagocytic activity via Rac1-mediated signaling pathway: Implications for bacterial infection

(2016) Cuixia Lu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Endothelial STAT3 Activation Increases Vascular Leakage Through Downregulating Tight Junction Proteins: Implications for Diabetic Retinopathy

(2016) Jang-Hyuk Yun et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Diabetic retinopathy

(2016) Tien Y. Wong et al.   Nature Reviews Disease Primers

Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration

(2015) L. Zhao et al.   EMBO Molecular Medicine

Macrophage SR-BI mediates efferocytosis via Src/PI3K/Rac1 signaling and reduces atherosclerotic lesion necrosis

(2015) Huan Tao et al.   JOURNAL OF LIPID RESEARCH

Intracerebroventricular Streptozotocin Injections as a Model of Alzheimer’s Disease: in Search of a Relevant Mechanism

(2015) Paweł Grieb   MOLECULAR NEUROBIOLOGY

Exploring the various aspects of the pathological role of vascular endothelial growth factor (VEGF) in diabetic retinopathy

(2015) Tapan Behl et al.   PHARMACOLOGICAL RESEARCH

Retinal microglia: Just bystander or target for therapy?

(2015) Marcus Karlstetter et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Local proliferation is the main source of rod microglia after optic nerve transection

(2015) Ti-Fei Yuan et al.   Scientific Reports

Qingkailing Suppresses the Activation of BV2 Microglial Cells by Inhibiting Hypoxia/Reoxygenation-Induced Inflammatory Responses

(2014) Lulu Mana et al.   Evidence-based Complementary and Alternative Medicine

Early spatiotemporal characterization of microglial activation in the retinas of rats with streptozotocin-induced diabetes

(2014) Xiaofei Chen et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Erythropoietin Exerts a Neuroprotective Function Against Glutamate Neurotoxicity in Experimental Diabetic Retina

(2014) L. Gu et al.   INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

The Role of Microglia in Diabetic Retinopathy

(2014) Jeffery G. Grigsby et al.   Journal of Ophthalmology

Neurodegeneration is an early event in diabetic retinopathy: therapeutic implications

(2012) Rafael Simó et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Global Prevalence and Major Risk Factors of Diabetic Retinopathy

(2012) J. W. Y. Yau et al.   DIABETES CARE

Intravitreal injection of erythropoietin protects against retinal vascular regression at the early stage of diabetic retinopathy in streptozotocin-induced diabetic rats

(2012) Junko Mitsuhashi et al.   EXPERIMENTAL EYE RESEARCH

Hypoxia in the Eye: A Two-Sided Coin

(2012) Christian Grimm et al.   HIGH ALTITUDE MEDICINE & BIOLOGY

Relationship between diabetic retinopathy, microalbuminuria and overt nephropathy, and twenty-year incidence follow-up of a sample of type 1 diabetic patients

(2012) Pedro Romero-Aroca et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Retinal Microglial Activation and Inflammation Induced by Amadori-Glycated Albumin in a Rat Model of Diabetes

(2011) A. S. Ibrahim et al.   DIABETES

Intervention With an Erythropoietin-Derived Peptide Protects Against Neuroglial and Vascular Degeneration During Diabetic Retinopathy

(2011) Carmel M. McVicar et al.   DIABETES

Inflammation in diabetic retinopathy

(2011) Johnny Tang et al.   PROGRESS IN RETINAL AND EYE RESEARCH

From oxygen to erythropoietin: Relevance of hypoxia for retinal development, health and disease

(2011) Christian Caprara et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Presence of retinopathy in type 1 diabetic patients is associated with subclinical macroangiopathy

(2011) Aleksandra Araszkiewicz et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

Low-dose erythropoietin inhibits oxidative stress and early vascular changes in the experimental diabetic retina

(2010) Q. Wang et al.   DIABETOLOGIA

Diabetic retinopathy

(2010) Ning Cheung et al.   LANCET

Effects of Intravitreal Erythropoietin Therapy for Patients with Chronic and Progressive Diabetic Macular Edema

(2010) Weiye Li et al.   OPHTHALMIC SURGERY LASERS & IMAGING