Tracking Uptake and Metabolism of Xenometallomycins Using a Multi-Isotope Tagging Strategy

A Salmochelin S4-inspired Ciprofloxacin Trojan Horse Conjugate

(2020) Thomas Sanderson et al.   ACS Infectious Diseases

Emerging Opportunities To Manipulate Metal Trafficking for Therapeutic Benefit

(2019) Elizabeth W. Hunsaker et al.   INORGANIC CHEMISTRY

Theranostic Gallium Siderophore Ciprofloxacin Conjugate with Broad Spectrum Antibiotic Potency

(2019) Apurva Pandey et al.   JOURNAL OF MEDICINAL CHEMISTRY

Functional genetic discovery of enzymes using full-scan mass spectrometry metabolomics

(2018) Amy A. Caudy et al.   Biochemistry and Cell Biology

Evaluation of a reducible disulfide linker for siderophore-mediated delivery of antibiotics

(2018) Wilma Neumann et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Esterase-Catalyzed Siderophore Hydrolysis Activates an Enterobactin–Ciprofloxacin Conjugate and Confers Targeted Antibacterial Activity

(2018) Wilma Neumann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

High-throughput metabolomic analysis predicts mode of action of uncharacterized antimicrobial compounds

(2018) Mattia Zampieri et al.   Science Translational Medicine

Total synthesis and antimicrobial evaluation of natural albomycins against clinical pathogens

(2018) Zihua Lin et al.   Nature Communications

Imaging of Pseudomonas aeruginosa infection with Ga-68 labelled pyoverdine for positron emission tomography

(2018) Milos Petrik et al.   Scientific Reports

Siderophore Conjugates of Daptomycin are Potent Inhibitors of Carbapenem Resistant Strains of Acinetobacter baumannii

(2018) Manuka Ghosh et al.   ACS Infectious Diseases

Multifunctional Desferrichrome Analogues as Versatile 89Zr(IV) Chelators for ImmunoPET Probe Development

(2017) Casey J. Adams et al.   MOLECULAR PHARMACEUTICS

Nontargeted Metabolomics Reveals the Multilevel Response to Antibiotic Perturbations

(2017) Mattia Zampieri et al.   Cell Reports

Characterization and prediction of the mechanism of action of antibiotics through NMR metabolomics

(2016) Verena Hoerr et al.   BMC MICROBIOLOGY

Catechol siderophores repress the pyochelin pathway and activate the enterobactin pathway in P seudomonas aeruginosa : an opportunity for siderophore-antibiotic conjugates development

(2016) Véronique Gasser et al.   ENVIRONMENTAL MICROBIOLOGY

Multidrug Efflux Pumps at the Crossroad between Antibiotic Resistance and Bacterial Virulence

(2016) Manuel Alcalde-Rico et al.   Frontiers in Microbiology

Siderophore–fluoroquinolone conjugates containing potential reduction-triggered linkers for drug release: synthesis and antibacterial activity

(2015) Cheng Ji et al.   BIOMETALS

Beyond iron: non-classical biological functions of bacterial siderophores

(2015) Timothy C. Johnstone et al.   DALTON TRANSACTIONS

In Vitro and In Vivo Comparison of Selected Ga-68 and Zr-89 Labelled Siderophores

(2015) Milos Petrik et al.   MOLECULAR IMAGING AND BIOLOGY

Probing linker design in citric acid–ciprofloxacin conjugates

(2014) Stephen J. Milner et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Enterobactin-Mediated Delivery of β-Lactam Antibiotics Enhances Antibacterial Activity against Pathogenic Escherichia coli

(2014) Tengfei Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Trihydroxamate Siderophore–Fluoroquinolone Conjugates Are Selective Sideromycin Antibiotics that Target Staphylococcus aureus

(2013) Timothy A. Wencewicz et al.   BIOCONJUGATE CHEMISTRY

Biscatecholate–Monohydroxamate Mixed Ligand Siderophore–Carbacephalosporin Conjugates are Selective Sideromycin Antibiotics that Target Acinetobacter baumannii

(2013) Timothy A. Wencewicz et al.   JOURNAL OF MEDICINAL CHEMISTRY

Staphyloferrin A as siderophore-component in fluoroquinolone-based Trojan horse antibiotics

(2013) Stephen J. Milner et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Exploiting bacterial iron acquisition: siderophore conjugates

(2012) Cheng Ji et al.   Future Medicinal Chemistry

Siderophore-Mediated Cargo Delivery to the Cytoplasm of Escherichia coli and Pseudomonas aeruginosa: Syntheses of Monofunctionalized Enterobactin Scaffolds and Evaluation of Enterobactin–Cargo Conjugate Uptake

(2012) Tengfei Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Syntheses of Siderophore–Drug Conjugates Using a Convergent Thiol–Maleimide System

(2012) Raúl E. Juárez-Hernández et al.   ACS Medicinal Chemistry Letters

In vitro and in vivo evaluation of selected 68Ga-siderophores for infection imaging

(2011) Milos Petrik et al.   NUCLEAR MEDICINE AND BIOLOGY

68Ga-Siderophores for PET Imaging of Invasive Pulmonary Aspergillosis: Proof of Principle

(2010) M. Petrik et al.   JOURNAL OF NUCLEAR MEDICINE

Utilization of microbial iron assimilation processes for the development of new antibiotics and inspiration for the design of new anticancer agents

(2009) Marvin J. Miller et al.   BIOMETALS

Sideromycins: tools and antibiotics

(2009) Volkmar Braun et al.   BIOMETALS

Radioiodination of 1-(2-deoxy-β-d-ribofuranosyl)-2,4-difluoro-5-iodobenzene (dRFIB), a putative thymidine mimic nucleoside for cell proliferation studies

(2008) Anke Stahlschmidt et al.   APPLIED RADIATION AND ISOTOPES

Imaging Hypoxia in Orthotopic Rat Liver Tumors with Iodine 124–labeled Iodoazomycin Galactopyranoside PET

(2008) Christopher C. Riedl et al.   RADIOLOGY