Characterizing CD38 Expression and Enzymatic Activity in the Brain of Spontaneously Hypertensive Stroke-Prone Rats

Characterizing the Neuroimaging and Histopathological Correlates of Cerebral Small Vessel Disease in Spontaneously Hypertensive Stroke-Prone Rats

(2021) Yousef Hannawi et al.   Frontiers in Neurology

CD38 in Neurodegeneration and Neuroinflammation

(2020) Serge Guerreiro et al.   Cells

White Matter Injury Is Associated with Reduced Manual Dexterity and Elevated Serum Ceramides in Subjects with Cerebral Small Vessel Disease

(2020) Yousef Hannawi et al.   CEREBROVASCULAR DISEASES

Inhibition of CD38 with the thiazoloquin(az)olin(on)e 78c protects the heart against post-ischemic injury

(2019) James Boslett et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Small vessel disease: mechanisms and clinical implications

(2019) Joanna M Wardlaw et al.   LANCET NEUROLOGY

Deletion of CD38 Suppresses Glial Activation and Neuroinflammation in a Mouse Model of Demyelination

(2019) Jureepon Roboon et al.   Frontiers in Cellular Neuroscience

PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation

(2019) Isabella Wimmer et al.   Frontiers in Immunology

The Multi-faceted Ecto-enzyme CD38: Roles in Immunomodulation, Cancer, Aging, and Metabolic Diseases

(2019) Kelly A. Hogan et al.   Frontiers in Immunology

Cerebral Small Vessel Disease (CSVD) – Lessons From the Animal Models

(2019) Muzaimi Mustapha et al.   Frontiers in Physiology

CD38, a Receptor with Multifunctional Activities: From Modulatory Functions on Regulatory Cell Subsets and Extracellular Vesicles, to a Target for Therapeutic Strategies

(2019) Fabio Morandi et al.   Cells

Characterization of CD38 in the major cell types of the heart: endothelial cells highly express CD38 with activation by hypoxia-reoxygenation triggering NAD(P)H depletion

(2018) James Boslett et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Blood–brain barrier leakage in relation to white matter hyperintensity volume and cognition in small vessel disease and normal aging

(2018) C. Eleana Zhang et al.   Brain Imaging and Behavior

CD38 produces nicotinic acid adenosine dinucleotide phosphate in the lysosome

(2018) Cheng Fang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic deletion of CD38 confers post-ischemic myocardial protection through preserved pyridine nucleotides

(2018) James Boslett et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Reversal of endothelial dysfunction reduces white matter vulnerability in cerebral small vessel disease in rats

(2018) Rikesh M. Rajani et al.   Science Translational Medicine

Hypertension

(2018) Suzanne Oparil et al.   Nature Reviews Disease Primers

Hypertension Is Associated with White Matter Disruption in Apparently Healthy Middle-Aged Individuals

(2018) Y. Hannawi et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Luteolinidin Protects the Postischemic Heart through CD38 Inhibition with Preservation of NAD(P)(H)

(2017) James Boslett et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Oxidative Stress and Hypertensive Diseases

(2017) Roxana Loperena et al.   MEDICAL CLINICS OF NORTH AMERICA

High Expression Levels of NADPH Oxidase 3 in the Cerebrum of Ten-Week-Old Stroke-Prone Spontaneously Hypertensive Rats

(2016) Akihiro Michihara et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism

(2016) Juliana Camacho-Pereira et al.   Cell Metabolism

CD38 Knockout Mice Show Significant Protection Against Ischemic Brain Damage Despite High Level Poly-ADP-Ribosylation

(2016) Aaron Long et al.   NEUROCHEMICAL RESEARCH

Alzheimer's disease pathology is attenuated in a CD38-deficient mouse model

(2015) Eran Blacher et al.   ANNALS OF NEUROLOGY

Depletion of NADP(H) due to CD38 activation triggers endothelial dysfunction in the postischemic heart

(2015) Levy A. Reyes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mapping NAD+ metabolism in the brain of ageing Wistar rats: potential targets for influencing brain senescence

(2013) Nady Braidy et al.   BIOGERONTOLOGY

Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration

(2013) Joanna M Wardlaw et al.   LANCET NEUROLOGY

The stroke-prone spontaneously hypertensive rat: still a useful model for post-GWAS genetic studies?

(2012) Toru Nabika et al.   HYPERTENSION RESEARCH

Staging and natural history of cerebrovascular pathology in dementia

(2012) V. Deramecourt et al.   NEUROLOGY

Is the Spontaneously Hypertensive Stroke Prone Rat a Pertinent Model of Sub Cortical Ischemic Stroke? A Systematic Review

(2011) Emma L. Bailey et al.   International Journal of Stroke

The Pathologic Cascade of Cerebrovascular Lesions in SHRSP: Is Erythrocyte Accumulation an Early Phase?

(2011) Stefanie Schreiber et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Cerebral small vessel endothelial structural changes predate hypertension in stroke-prone spontaneously hypertensive rats: a blinded, controlled immunohistochemical study of 5- to 21-week-old rats

(2011) E. L. Bailey et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges

(2010) Leonardo Pantoni   LANCET NEUROLOGY