Deletion of CD38 Suppresses Glial Activation and Neuroinflammation in a Mouse Model of Demyelination

CD38 positively regulates postnatal development of astrocytes cell-autonomously and oligodendrocytes non-cell-autonomously

(2017) Tsuyoshi Hattori et al.   GLIA

Transplanted miR-219-overexpressing oligodendrocyte precursor cells promoted remyelination and improved functional recovery in a chronic demyelinated model

(2017) Hong-Bin Fan et al.   Scientific Reports

Identification of gene expression patterns crucially involved in experimental autoimmune encephalomyelitis and multiple sclerosis

(2016) Martin M. Herrmann et al.   Disease Models & Mechanisms

Astrocyte-targeted production of interleukin-6 reduces astroglial and microglial activation in the cuprizone demyelination model: Implications for myelin clearance and oligodendrocyte maturation

(2016) Filip Petković et al.   GLIA

CXCL10 Triggers Early Microglial Activation in the Cuprizone Model

(2015) Tim Clarner et al.   JOURNAL OF IMMUNOLOGY

The sphingosine 1-phosphate receptor agonist FTY720 is neuroprotective after cuprizone-induced CNS demyelination

(2014) A Slowik et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cellular and molecular neuropathology of the cuprizone mouse model: Clinical relevance for multiple sclerosis

(2014) Jelle Praet et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

DISC1 (Disrupted-in-Schizophrenia-1) Regulates Differentiation of Oligodendrocytes

(2014) Tsuyoshi Hattori et al.   PLoS One

Friends or Foes? Relational Dissonance and Adolescent Psychological Wellbeing

(2014) Lyndal Bond et al.   PLoS One

Glial response during cuprizone-induced de- and remyelination in the CNS: lessons learned

(2014) Viktoria Gudi et al.   Frontiers in Cellular Neuroscience

NAD+ protects against EAE by regulating CD4+ T-cell differentiation

(2014) Stefan G. Tullius et al.   Nature Communications

The NAD-dependent deacetylase sirtuin 2 is a suppressor of microglial activation and brain inflammation

(2013) Teresa Faria Pais et al.   EMBO JOURNAL

Sildenafil (Viagra) Protective Effects on Neuroinflammation: The Role of iNOS/NO System in an Inflammatory Demyelination Model

(2013) Catarina Raposo et al.   MEDIATORS OF INFLAMMATION

Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models

(2013) Bing Gong et al.   NEUROBIOLOGY OF AGING

Astrocytes regulate myelin clearance through recruitment of microglia during cuprizone-induced demyelination

(2012) Thomas Skripuletz et al.   BRAIN

Progressive multiple sclerosis: pathology and pathogenesis

(2012) Hans Lassmann et al.   Nature Reviews Neurology

CD38 deficiency in the tumor microenvironment attenuates glioma progression and modulates features of tumor-associated microglia/macrophages

(2012) Ayelet Levy et al.   NEURO-ONCOLOGY

Neurobiological effects of sphingosine 1-phosphate receptor modulation in the cuprizone model

(2011) Hye Jung Kim et al.   FASEB JOURNAL

Sphingosine 1-phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions

(2010) Ruben Van Doorn et al.   GLIA

Axon-oligodendrocyte interactions during developmental myelination, demyelination and repair

(2010) Gabrièle Piaton et al.   JOURNAL OF NEUROCHEMISTRY

Elevated Phosphatidylinositol 3,4,5-Trisphosphate in Glia Triggers Cell-Autonomous Membrane Wrapping and Myelination

(2010) S. Goebbels et al.   JOURNAL OF NEUROSCIENCE

DISC1 regulates cell–cell adhesion, cell–matrix adhesion and neurite outgrowth

(2010) T Hattori et al.   MOLECULAR PSYCHIATRY

CXCR4 promotes differentiation of oligodendrocyte progenitors and remyelination

(2010) J. R. Patel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation

(2010) J. W. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD38 regulation in activated astrocytes: Implications for neuroinflammation and HIV-1 brain infection

(2009) Wei Kou et al.   JOURNAL OF NEUROSCIENCE RESEARCH

CD38 Facilitates Recovery from Traumatic Brain Injury

(2009) Ayelet Levy et al.   JOURNAL OF NEUROTRAUMA

Pattern of axonal injury in murine myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis: Implications for multiple sclerosis

(2008) Eva Herrero-Herranz et al.   NEUROBIOLOGY OF DISEASE

Evolution and Function of the ADP Ribosyl Cyclase/CD38 Gene Family in Physiology and Pathology

(2008) Fabio Malavasi et al.   PHYSIOLOGICAL REVIEWS