标题
Multivalent Aptamer Approach: Designs, Strategies, and Applications
作者
关键词
-
出版物
Micromachines
Volume 13, Issue 3, Pages 436
出版商
MDPI AG
发表日期
2022-03-14
DOI
10.3390/mi13030436
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Chitosan-gold based aptamer functionalized nano dual drug delivery system for improved glioblastoma treatment
- (2021) Anbazhagan Sathiyaseelan et al. CARBOHYDRATE POLYMERS
- Synthesis and Evaluation of Multivalent Nitroimidazole-based Near-Infrared Fluorescent Agents for Neuroblastoma and Colon Cancer Imaging
- (2021) Young-Do Kwon et al. BIOORGANIC CHEMISTRY
- Multivalent Aptamer‐Functionalized Single‐Strand RNA Origami as Effective, Target‐Specific Anticoagulants with Corresponding Reversal Agents
- (2021) Abhichart Krissanaprasit et al. Advanced Healthcare Materials
- Multivalent Aptamer Functionalized Ag 2 S Nanodots/Hybrid Cell Membrane‐Coated Magnetic Nanobioprobe for the Ultrasensitive Isolation and Detection of Circulating Tumor Cells
- (2020) Caiping Ding et al. ADVANCED FUNCTIONAL MATERIALS
- Aptamers as Versatile Ligands for Biomedical and Pharmaceutical Applications
- (2020) Baozhang Guan et al. International Journal of Nanomedicine
- Engineering Multivalence Aptamer Probes for Amplified and Label-Free Detection of Antibiotics in Aquatic Products
- (2020) Yong Zhang et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- AS1411 aptamer-functionalized chitosan-silica nanoparticles for targeted delivery of epigallocatechin gallate to the SKOV-3 ovarian cancer cell lines
- (2020) Leila Alizadeh et al. JOURNAL OF NANOPARTICLE RESEARCH
- Fluidic Multivalent Membrane Nanointerface Enables Synergetic Enrichment of Circulating Tumor Cells with High Efficiency and Viability
- (2020) Lingling Wu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- In Situ-Generated Multivalent Aptamer Network for Efficient Capture and Sensitive Electrochemical Detection of Circulating Tumor Cells in Whole Blood
- (2020) Jianmei Yang et al. ANALYTICAL CHEMISTRY
- In Situ Synthesis of an Aptamer‐Based Polyvalent Antibody Mimic on the Cell Surface for Enhanced Interactions between Immune and Cancer Cells
- (2020) Peng Shi et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- DNA Nanostructures for Targeted Antimicrobial Delivery
- (2020) Ioanna Mela et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Highly Sensitive Minimal Residual Disease Detection by Biomimetic Multivalent Aptamer Nanoclimber Functionalized Microfluidic Chip
- (2020) Yilong Liu et al. Small
- Rolling Circle Amplification-Based Polyvalent Molecular Beacon Probe-Assisted Signal Amplification Strategies for Sensitive Detection of B16 Cells
- (2020) Zhiqing Zhang et al. ACS Biomaterials-Science & Engineering
- Convenient Construction of Orthogonal Dual Aptamer-Based Plasmonic Immunosandwich Assay for Probing Protein Disease Markers in Complex Samples and Living Animals
- (2020) Yanyan Ma et al. ACS Sensors
- Biodegradable Mesoporous Organosilica Nanosheets for Chemotherapy/Mild Thermotherapy of Cancer: Fast Internalization, High Cellular Uptake, and High Drug Loading
- (2020) Lizhu Chen et al. ACS Applied Materials & Interfaces
- Developing a dual-RCA microfluidic platform for sensitive E. coli O157:H7 whole-cell detections
- (2020) Yuqian Jiang et al. ANALYTICA CHIMICA ACTA
- Barcoded DNA origami structures for multiplexed optimization and enrichment of DNA-based protein-binding cavities
- (2020) Ali Aghebat Rafat et al. Nature Chemistry
- Bioinspired DNA Nanointerface with Anisotropic Aptamers for Accurate Capture of Circulating Tumor Cells
- (2020) Weiwei Qin et al. Advanced Science
- Immobilization Techniques for Aptamers on Gold Electrodes for the Electrochemical Detection of Proteins: A Review
- (2020) Franziska V. Oberhaus et al. Biosensors-Basel
- A novel method combining aptamer-Ag10NPs based microfluidic biochip with bright field imaging for detection of KPC-2-expressing bacteria
- (2020) Jing Chen et al. ANALYTICA CHIMICA ACTA
- MicroRNA-responsive release of Cas9/sgRNA from DNA nanoflower for cytosolic protein delivery and enhanced genome editing
- (2020) Jinjin Shi et al. BIOMATERIALS
- Zinc Ion-Stabilized Aptamer-Targeted Black Phosphorus Nanosheets for Enhanced Photothermal/Chemotherapy Against Prostate Cancer
- (2020) Li Gao et al. Frontiers in Bioengineering and Biotechnology
- Effect of an alkyl spacer on the morphology and internalization of MUC1 aptamer‐naphthalimide amphiphiles for targeting and imaging triple negative breast cancer cells
- (2020) Huihui Kuang et al. Bioengineering & Translational Medicine
- Design of a multivalent bifunctional chelator for diagnostic64Cu PET imaging in Alzheimer’s disease
- (2020) Hong-Jun Cho et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A regenerative NanoOctopus based on multivalent-aptamer functionalized magnetic microparticles for effective cell capture in whole blood
- (2019) Yongli Chen et al. ANALYTICAL CHEMISTRY
- Artificial Antibody with Site-Enhanced Multivalent Aptamers for Specific Capture of Circulating Tumor Cells
- (2019) Lukuan Liu et al. ANALYTICAL CHEMISTRY
- Efficient Intracellular Delivery of RNase A Using DNA Origami Carriers
- (2019) Shuai Zhao et al. ACS Applied Materials & Interfaces
- Virus-Mimicking Cell Capture Using Heterovalency Magnetic DNA Nanoclaws
- (2019) Zhiru Wang et al. ACS Applied Materials & Interfaces
- Nonviolent Self-Catabolic DNAzyme Nanosponges for Smart Anticancer Drug Delivery
- (2019) Jing Wang et al. ACS Nano
- Aptamer surface functionalization of microfluidic devices using dendrimers as multi-handled templates and its application in sensitive detections of foodborne pathogenic bacteria
- (2019) Xingkai Hao et al. ANALYTICA CHIMICA ACTA
- Biospecific Monolayer Coating for Multivalent Capture of Circulating Tumor Cells with High Sensitivity
- (2019) Jie Chen et al. ADVANCED FUNCTIONAL MATERIALS
- Aptamer-Functionalized and Gold Nanoparticle Array-Decorated Magnetic Graphene Nanosheets Enable Multiplexed and Sensitive Electrochemical Detection of Rare Circulating Tumor Cells in Whole Blood
- (2019) Baoting Dou et al. ANALYTICAL CHEMISTRY
- Target capturing performance of microfluidic channel surface immobilized aptamers: the effects of spacer lengths
- (2019) Yubo Qin et al. BIOMEDICAL MICRODEVICES
- Multivalent Aptamer-modified DNA Origami as Drug Delivery System for Targeted Cancer Therapy
- (2019) Mengyao Cao et al. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
- An aptamer cocktail-based electrochemical aptasensor for direct capture and rapid detection of tetracycline in honey
- (2019) Yunfei Huang et al. MICROCHEMICAL JOURNAL
- Designer DNA architecture offers precise and multivalent spatial pattern-recognition for viral sensing and inhibition
- (2019) Paul S. Kwon et al. Nature Chemistry
- Aptamer-Functionalized DNA Origami for Targeted Codelivery of Antisense Oligonucleotides and Doxorubicin to Enhance Therapy in Drug-Resistant Cancer Cells
- (2019) Qingshan Pan et al. ACS Applied Materials & Interfaces
- Multivalent HER2-binding polymer conjugates facilitate rapid endocytosis and enhance intracellular drug delivery
- (2019) D. Christopher Radford et al. JOURNAL OF CONTROLLED RELEASE
- Aptamers Chemistry: Chemical Modifications and Conjugation Strategies
- (2019) Fadwa Odeh et al. MOLECULES
- An Efficient Cell-Targeting Drug Delivery System Based on Aptamer-Modified Mesoporous Silica Nanoparticles
- (2019) Yang Yang et al. Nanoscale Research Letters
- Monolayer Nanosheets with an Extremely High Drug Loading toward Controlled Delivery and Cancer Theranostics
- (2018) Liuqi Peng et al. ADVANCED MATERIALS
- Spherical Nucleic Acid Nanoparticles: Therapeutic Potential
- (2018) Chintan H. Kapadia et al. BIODRUGS
- Promoting Multivalent Antibody–Antigen Interactions by Tethering Antibody Molecules on a PEGylated Dendrimer-Supported Lipid Bilayer
- (2018) Po-Ying Yeh et al. BIOMACROMOLECULES
- Implication of multivalent aptamers in DNA and DNA–RNA hybrid structures for efficient drug delivery in vitro and in vivo
- (2018) Yoon Young Kang et al. JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
- An aptamer-enabled DNA nanobox for protein sensing
- (2018) Marco S.L. Tang et al. Nanomedicine-Nanotechnology Biology and Medicine
- A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo
- (2018) Suping Li et al. NATURE BIOTECHNOLOGY
- Multivalent glycosylated Cu:CdS quantum dots as a platform for rapid bacterial discrimination and detection
- (2018) Peng Qi et al. SENSORS AND ACTUATORS B-CHEMICAL
- Utilization of aptamer-functionalized magnetic beads for highly accurate fluorescent detection of mercury (II) in environment and food
- (2018) Chunyan Sun et al. SENSORS AND ACTUATORS B-CHEMICAL
- A fluorescent biosensor based on molybdenum disulfide nanosheets and protein aptamer for sensitive detection of carcinoembryonic antigen
- (2018) Lianjing Zhao et al. SENSORS AND ACTUATORS B-CHEMICAL
- Dual-aptamer based electrochemical sandwich biosensor for MCF-7 human breast cancer cells using silver nanoparticle labels and a poly(glutamic acid)/MWNT nanocomposite
- (2018) Samira Yazdanparast et al. MICROCHIMICA ACTA
- Site-specific anchoring aptamer C2NP on DNA origami nanostructures for cancer treatment
- (2018) Pengchao Sun et al. RSC Advances
- Bioinspired Engineering of a Multivalent Aptamer-Functionalized Nanointerface to Enhance the Capture and Release of Circulating Tumor Cells
- (2018) Yanling Song et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Enhanced Targeted Gene Transduction: AAV2 Vectors Conjugated to Multiple Aptamers via Reducible Disulfide Linkages
- (2017) Yuan Wu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- MUC1 aptamer-capped mesoporous silica nanoparticles for controlled drug delivery and radio-imaging applications
- (2017) Lluis Pascual et al. Nanomedicine-Nanotechnology Biology and Medicine
- A simple dendrimer-aptamer based microfluidic platform for E. coli O157:H7 detection and signal intensification by rolling circle amplification
- (2017) Yuqian Jiang et al. SENSORS AND ACTUATORS B-CHEMICAL
- Biodegradable, multifunctional DNAzyme nanoflowers for enhanced cancer therapy
- (2017) Yi Jin et al. NPG Asia Materials
- Effect of Chemical Modifications on Aptamer Stability in Serum
- (2017) Christina Kratschmer et al. Nucleic Acid Therapeutics
- Aptamer Internalization via Endocytosis Inducing S-Phase Arrest and Priming Maver-1 Lymphoma Cells for Cytarabine Chemotherapy
- (2017) Huan Li et al. Theranostics
- Stable, polyvalent aptamer-conjugated near-infrared fluorescent nanocomposite for high-performance cancer cell-targeted imaging and therapy
- (2017) Yan-Jun Zhu et al. Journal of Materials Chemistry B
- Aptamer-coded DNA nanoparticles for targeted doxorubicin delivery using pH-sensitive spacer
- (2017) Pengwei Zhang et al. Frontiers of Chemical Science and Engineering
- Self-Assembled DNA Nanocentipede as Multivalent Drug Carrier for Targeted Delivery
- (2016) Wenshan Li et al. ACS Applied Materials & Interfaces
- Molecularly Imprinted Polymers with DNA Aptamer Fragments as Macromonomers
- (2016) Zijie Zhang et al. ACS Applied Materials & Interfaces
- Biostable L-DNA-Templated Aptamer-Silver Nanoclusters for Cell-Type-Specific Imaging at Physiological Temperature
- (2016) Gui-Mei Han et al. ANALYTICAL CHEMISTRY
- On-chip, aptamer-based sandwich assay for detection of glycated hemoglobins via magnetic beads
- (2016) Jinglun Li et al. BIOSENSORS & BIOELECTRONICS
- Aptamer–MIP hybrid receptor for highly sensitive electrochemical detection of prostate specific antigen
- (2016) Pawan Jolly et al. BIOSENSORS & BIOELECTRONICS
- The Effects of Spacer Length and Composition on Aptamer-Mediated Cell-Specific Targeting with Nanoscale PEGylated Liposomal Doxorubicin
- (2016) Hang Xing et al. CHEMBIOCHEM
- Blurring the Role of Oligonucleotides: Spherical Nucleic Acids as a Drug Delivery Vehicle
- (2016) Xuyu Tan et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Multivalent Aptamer-RNA Conjugates for Simple and Efficient Delivery of Doxorubicin/siRNA into Multidrug-Resistant Cells
- (2016) Hyosook Jeong et al. MACROMOLECULAR BIOSCIENCE
- Double targeting, controlled release and reversible delivery of daunorubicin to cancer cells by polyvalent aptamers-modified gold nanoparticles
- (2016) Seyed Mohammad Taghdisi et al. Materials Science & Engineering C-Materials for Biological Applications
- A highly versatile platform based on geometrically well-defined 3D DNA nanostructures for selective recognition and positioning of multiplex targets
- (2016) Ziwen Dai et al. Nanoscale
- Targeted Delivery of Epirubicin to Cancer Cells by Polyvalent Aptamer System in vitro and in vivo
- (2016) Rezvan Yazdian-Robati et al. PHARMACEUTICAL RESEARCH
- Enhanced and Differential Capture of Circulating Tumor Cells from Lung Cancer Patients by Microfluidic Assays Using Aptamer Cocktail
- (2016) Libo Zhao et al. Small
- A DNA aptamer recognising a malaria protein biomarker can function as part of a DNA origami assembly
- (2016) Maia Godonoga et al. Scientific Reports
- Aptamer-PEG-modified Fe3O4@Mn as a novel T1- and T2- dual-model MRI contrast agent targeting hypoxia-induced cancer stem cells
- (2016) Haitao Zhu et al. Scientific Reports
- Photothermal Therapeutic Response of Cancer Cells to Aptamer–Gold Nanoparticle-Hybridized Graphene Oxide under NIR Illumination
- (2015) Lingyan Yang et al. ACS Applied Materials & Interfaces
- Aggregation-Induced Emission Luminogen-Embedded Silica Nanoparticles Containing DNA Aptamers for Targeted Cell Imaging
- (2015) Xiaoyan Wang et al. ACS Applied Materials & Interfaces
- On-chip FRET Graphene Oxide Aptasensor: Quantitative Evaluation of Enhanced Sensitivity by Aptamer with a Double-stranded DNA Spacer
- (2015) Yuko UENO et al. ANALYTICAL SCIENCES
- Multimerization of ERBB2/HER2 specific aptamer leads to improved receptor binding
- (2015) Georg Mahlknecht et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Dual aptamer-immobilized surfaces for improved affinity through multiple target binding in potentiometric thrombin biosensing
- (2015) Tatsuro Goda et al. BIOSENSORS & BIOELECTRONICS
- Aptamer density dependent cellular uptake of lipid-capped polymer nanoparticles for polyvalent targeted delivery of vinorelbine to cancer cells
- (2015) Zhenbao Liu et al. RSC Advances
- A Controllable Aptamer-Based Self-Assembled DNA Dendrimer for High Affinity Targeting, Bioimaging and Drug Delivery
- (2015) Huimin Zhang et al. Scientific Reports
- Facile Supermolecular Aptamer Inhibitors of L-Selectin
- (2015) Elizabeth K. Chang et al. PLoS One
- A Systematic Study of the Features Critical for Designing a High Avidity Multivalent Aptamer
- (2015) Xiaoching Zhao et al. Nucleic Acid Therapeutics
- Multivalent comb-type aptamer–siRNA conjugates for efficient and selective intracellular delivery
- (2014) Hyundong Yoo et al. CHEMICAL COMMUNICATIONS
- Activatable Fluorescence/MRI Bimodal Platform for Tumor Cell Imaging via MnO2 Nanosheet–Aptamer Nanoprobe
- (2014) Zilong Zhao et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Effect of Polyethylene Glycol, Alkyl, and Oligonucleotide Spacers on the Binding, Secondary Structure, and Self-Assembly of Fractalkine Binding FKN-S2 Aptamer-Amphiphiles
- (2014) Brett Waybrant et al. LANGMUIR
- Multivalent DNA Nanospheres for Enhanced Capture of Cancer Cells in Microfluidic Devices
- (2013) Weian Sheng et al. ACS Nano
- A polyvalent aptamer system for targeted drug delivery
- (2013) Zhiqing Zhang et al. BIOMATERIALS
- Design of PEG-aptamer two piece macromolecules as convenient and integrated sensing platform: Application to the label free detection of small size molecules
- (2013) Akhtar Hayat et al. BIOSENSORS & BIOELECTRONICS
- Aptamer cocktails: Enhancement of sensing signals compared to single use of aptamers for detection of bacteria
- (2013) Yeon Seok Kim et al. BIOSENSORS & BIOELECTRONICS
- Spherical Nucleic Acids
- (2012) Joshua I. Cutler et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Specific capture and temperature-mediated release of cells in an aptamer-based microfluidic device
- (2012) Jing Zhu et al. LAB ON A CHIP
- Bioinspired multivalent DNA network for capture and release of cells
- (2012) W. Zhao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cell adhesion on an artificial extracellular matrix using aptamer-functionalized PEG hydrogels
- (2011) Niancao Chen et al. BIOMATERIALS
- Characterization of Optimal Aptamer-Microarray Binding Chemistry and Spacer Design
- (2011) G. Zhu et al. CHEMICAL ENGINEERING & TECHNOLOGY
- Towards a rational spacer design for bivalent inhibition of estrogen receptor
- (2011) Alexander Bujotzek et al. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
- Aptamer sandwich assays: label-free and fluorescence investigations of heterogeneous binding events
- (2010) Katie A. Edwards et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Aptamers as therapeutics
- (2010) Anthony D. Keefe et al. NATURE REVIEWS DRUG DISCOVERY
- A multivalent DNA aptamer specific for the B-cell receptor on human lymphoma and leukemia
- (2010) Prabodhika R. Mallikaratchy et al. NUCLEIC ACIDS RESEARCH
- Enhancement of Aptamer Microarray Sensitivity through Spacer Optimization and Avidity Effect
- (2009) Yeh-Hsing Lao et al. ANALYTICAL CHEMISTRY
- Novel Designs of Multivalent Anti-CD20 Humanized Antibodies as Improved Lymphoma Therapeutics
- (2008) E. A. Rossi et al. CANCER RESEARCH
- Polyvalent DNA Nanoparticle Conjugates Stabilize Nucleic Acids
- (2008) Dwight S. Seferos et al. NANO LETTERS
- Self-assembled DNA nanostructures for distance-dependent multivalent ligand–protein binding
- (2008) Sherri Rinker et al. Nature Nanotechnology
- Improvement of Aptamer Affinity by Dimerization
- (2008) Hijiri Hasegawa et al. SENSORS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation