A Role for Ceramides, but Not Sphingomyelins, as Antagonists of Insulin Signaling and Mitochondrial Metabolism in C2C12 Myotubes

Characterization of the role of sphingomyelin synthase 2 in glucose metabolism in whole-body and peripheral tissues in mice

(2016) Masayuki Sugimoto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

CrossTalk opposing view: Intramyocellular ceramide accumulation does not modulate insulin resistance

(2016) Max C. Petersen et al.   JOURNAL OF PHYSIOLOGY-LONDON

CrossTalk proposal: Intramyocellular ceramide accumulation does modulate insulin resistance

(2016) Scott A. Summers et al.   JOURNAL OF PHYSIOLOGY-LONDON

Ganglioside GM3 as a gatekeeper of obesity-associated insulin resistance: Evidence and mechanisms

(2015) Christopher Lipina et al.   FEBS LETTERS

Ceramides – Lipotoxic Inducers of Metabolic Disorders

(2015) Bhagirath Chaurasia et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Obesity-Induced CerS6-Dependent C16:0 Ceramide Production Promotes Weight Gain and Glucose Intolerance

(2014) Sarah M. Turpin et al.   Cell Metabolism

C16:0-Ceramide Signals Insulin Resistance

(2014) Timothy Hla et al.   Cell Metabolism

CerS2 Haploinsufficiency Inhibits β-Oxidation and Confers Susceptibility to Diet-Induced Steatohepatitis and Insulin Resistance

(2014) Suryaprakash Raichur et al.   Cell Metabolism

An FGF21-Adiponectin-Ceramide Axis Controls Energy Expenditure and Insulin Action in Mice

(2013) William L. Holland et al.   Cell Metabolism

Ceramides and Glucosylceramides Are Independent Antagonists of Insulin Signaling

(2013) Jose A. Chavez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ablation of Dihydroceramide Desaturase 1, a Therapeutic Target for the Treatment of Metabolic Diseases, Simultaneously Stimulates Anabolic and Catabolic Signaling

(2013) M. M. Siddique et al.   MOLECULAR AND CELLULAR BIOLOGY

A sensitive cell-based method to screen for selective inhibitors of SMS1 or SMS2 using HPLC and a fluorescent substrate

(2012) Kota Zama et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Fenretinide Prevents Lipid-induced Insulin Resistance by Blocking Ceramide Biosynthesis

(2012) Benjamin T. Bikman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic Modification of Sphingomyelin in Lipid Microdomains Controls Development of Obesity, Fatty Liver, and Type 2 Diabetes

(2011) Susumu Mitsutake et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid–induced ceramide biosynthesis in mice

(2011) William L. Holland et al.   JOURNAL OF CLINICAL INVESTIGATION

Reducing Plasma Membrane Sphingomyelin Increases Insulin Sensitivity

(2011) Z. Li et al.   MOLECULAR AND CELLULAR BIOLOGY

Tricyclodecan-9-yl-Xanthogenate (D609) Mechanism of Actions: A Mini-Review of Literature

(2011) Rao Muralikrishna Adibhatla et al.   NEUROCHEMICAL RESEARCH

Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin

(2010) William L Holland et al.   NATURE MEDICINE

PAQRs: A Counteracting Force to Ceramides?

(2009) W. L. Holland et al.   MOLECULAR PHARMACOLOGY

Glycosphingolipids and insulin resistance

(2009) Mirjam Langeveld et al.   PROGRESS IN LIPID RESEARCH