CrossTalk proposal: Intramyocellular ceramide accumulation does modulate insulin resistance

Serum sphingolipids: relationships to insulin sensitivity and changes with exercise in humans

(2015) Bryan C. Bergman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Targeted Induction of Ceramide Degradation Leads to Improved Systemic Metabolism and Reduced Hepatic Steatosis

(2015) Jonathan Y. Xia et al.   Cell Metabolism

Exercise and Weight Loss Improve Muscle Mitochondrial Respiration, Lipid Partitioning, and Insulin Sensitivity After Gastric Bypass Surgery

(2015) Paul M. Coen et al.   DIABETES

Effect of pioglitazone on plasma ceramides in adults with metabolic syndrome

(2015) Jeremy T. Warshauer et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Ceramides – Lipotoxic Inducers of Metabolic Disorders

(2015) Bhagirath Chaurasia et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Effects of acute lipid overload on skeletal muscle insulin resistance, metabolic flexibility, and mitochondrial performance

(2014) John J. Dubé et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Obesity-Induced CerS6-Dependent C16:0 Ceramide Production Promotes Weight Gain and Glucose Intolerance

(2014) Sarah M. Turpin et al.   Cell Metabolism

Skeletal muscle ceramide species in men with abdominal obesity

(2014) Maria Pia de la Maza et al.   Journal of Nutrition Health & Aging

Role of diacylglycerol activation of PKCθ in lipid-induced muscle insulin resistance in humans

(2014) Julia Szendroedi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of sphingolipid synthesis improves dyslipidemia in the diet-induced hamster model of insulin resistance: Evidence for the role of sphingosine and sphinganine in hepatic VLDL-apoB100 overproduction

(2013) Mark J. Dekker et al.   ATHEROSCLEROSIS

An FGF21-Adiponectin-Ceramide Axis Controls Energy Expenditure and Insulin Action in Mice

(2013) William L. Holland et al.   Cell Metabolism

Mechanisms Underlying the Onset of Oral Lipid-Induced Skeletal Muscle Insulin Resistance in Humans

(2013) B. Nowotny et al.   DIABETES

Plasma ceramides are elevated in female children and adolescents with type 2 diabetes

(2013) Ximena Lopez et al.   JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM

Reduced skeletal muscle oxidative capacity and elevated ceramide but not diacylglycerol content in severe obesity

(2013) P.M. Coen et al.   Obesity

Ceramides Contained in LDL Are Elevated in Type 2 Diabetes and Promote Inflammation and Skeletal Muscle Insulin Resistance

(2012) J. Boon et al.   DIABETES

Plasma sphingolipids are biomarkers of metabolic syndrome in non-human primates maintained on a Western-style diet

(2012) J T Brozinick et al.   INTERNATIONAL JOURNAL OF OBESITY

Fenretinide Prevents Lipid-induced Insulin Resistance by Blocking Ceramide Biosynthesis

(2012) Benjamin T. Bikman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin Resistance, Ceramide Accumulation, and Endoplasmic Reticulum Stress in Human Chronic Alcohol-Related Liver Disease

(2012) Lisa Longato et al.   Oxidative Medicine and Cellular Longevity

Skeletal Muscle Triglycerides, Diacylglycerols, and Ceramides in Insulin Resistance: Another Paradox in Endurance-Trained Athletes?

(2011) F. Amati et al.   DIABETES

Effects of weight loss and exercise on insulin resistance, and intramyocellular triacylglycerol, diacylglycerol and ceramide

(2011) J. J. Dubé et al.   DIABETOLOGIA

Reducing Plasma Membrane Sphingomyelin Increases Insulin Sensitivity

(2011) Z. Li et al.   MOLECULAR AND CELLULAR BIOLOGY

Inhibition of De Novo Ceramide Synthesis Reverses Diet-Induced Insulin Resistance and Enhances Whole-Body Oxygen Consumption

(2010) J. R. Ussher et al.   DIABETES

Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin

(2010) William L Holland et al.   NATURE MEDICINE

Central role of ceramide biosynthesis in body weight regulation, energy metabolism, and the metabolic syndrome

(2009) Guang Yang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Insulin Resistance Is Associated With Higher Intramyocellular Triglycerides in Type I but Not Type II Myocytes Concomitant With Higher Ceramide Content

(2009) P. M. Coen et al.   DIABETES

Exercise-induced alterations in intramyocellular lipids and insulin resistance: the athlete's paradox revisited

(2008) John J. Dubé et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Plasma Ceramides Are Elevated in Obese Subjects With Type 2 Diabetes and Correlate With the Severity of Insulin Resistance

(2008) J. M. Haus et al.   DIABETES

Human skeletal muscle ceramide content is not a major factor in muscle insulin sensitivity

(2008) M. Skovbro et al.   DIABETOLOGIA