Regulation of Amyloid β Oligomer Binding to Neurons and Neurotoxicity by the Prion Protein-mGluR5 Complex
出版年份 2016 全文链接
标题
Regulation of Amyloid β Oligomer Binding to Neurons and Neurotoxicity by the Prion Protein-mGluR5 Complex
作者
关键词
-
出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 291, Issue 42, Pages 21945-21955
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2016-08-26
DOI
10.1074/jbc.m116.738286
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- The prion protein selectively binds to and modulates the content of purinergic receptor P2X4R
- (2016) Mariana V. Carneiro et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Prion protein in exosomes: partnering Aβ peptides and driving fibrilization
- (2016) Vilma R. Martins et al. JOURNAL OF NEUROCHEMISTRY
- Selective Disruption of Metabotropic Glutamate Receptor 5-Homer Interactions Mimics Phenotypes of Fragile X Syndrome in Mice
- (2016) W. Guo et al. JOURNAL OF NEUROSCIENCE
- Metabotropic glutamate receptor 5 couples cellular prion protein to intracellular signalling in Alzheimer’s disease
- (2015) Laura T. Haas et al. BRAIN
- The multivesicular body is the major internal site of prion conversion
- (2015) Y.-I. Yim et al. JOURNAL OF CELL SCIENCE
- Inhibition of Group I Metabotropic Glutamate Receptors Reverses Autistic-Like Phenotypes Caused by Deficiency of the Translation Repressor eIF4E Binding Protein 2
- (2015) A. Aguilar-Valles et al. JOURNAL OF NEUROSCIENCE
- Fragile X mice have robust mGluR5-dependent alterations of social behaviour in the Automated Tube Test
- (2015) C.E.F. de Esch et al. NEUROBIOLOGY OF DISEASE
- Neuronal stress signaling and eIF2α phosphorylation as molecular links between Alzheimer's disease and diabetes
- (2015) Mychael V. Lourenco et al. PROGRESS IN NEUROBIOLOGY
- Metabotropic glutamate receptor 5, and its trafficking molecules Norbin and Tamalin, are increased in the CA1 hippocampal region of subjects with schizophrenia
- (2015) Natalie Matosin et al. SCHIZOPHRENIA RESEARCH
- GABA receptor subunit distribution and FMRP–mGluR5 signaling abnormalities in the cerebellum of subjects with schizophrenia, mood disorders, and autism
- (2015) S. Hossein Fatemi et al. SCHIZOPHRENIA RESEARCH
- Neuroprotective effect of cellular prion protein (PrPC) is related with activation of alpha7 nicotinic acetylcholine receptor (α7nAchR)-mediated autophagy flux
- (2015) Jae-Kyo Jeong et al. Oncotarget
- PrPC signalling in neurons: From basics to clinical challenges
- (2014) Théo Z. Hirsch et al. BIOCHIMIE
- Therapeutic Molecules and Endogenous Ligands Regulate the Interaction between Brain Cellular Prion Protein (PrPC) and Metabotropic Glutamate Receptor 5 (mGluR5)
- (2014) Laura T. Haas et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Aβ induces its own prion protein N-terminal fragment (PrPN1)–mediated neutralization in amorphous aggregates
- (2014) Maxime Béland et al. NEUROBIOLOGY OF AGING
- Dysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and Autism
- (2014) Simona D’Antoni et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- mGlu5 receptors and cellular prion protein mediate amyloid-β-facilitated synaptic long-term depression in vivo
- (2014) Neng-Wei Hu et al. Nature Communications
- Metabotropic glutamate receptor 5 knockout reduces cognitive impairment and pathogenesis in a mouse model of Alzheimer's disease
- (2014) Alison Hamilton et al. Molecular Brain
- Increased prion protein processing and expression of metabotropic glutamate receptor 1 in a mouse model of Alzheimer's disease
- (2013) Valeriy G. Ostapchenko et al. JOURNAL OF NEUROCHEMISTRY
- The Prion Protein Ligand, Stress-Inducible Phosphoprotein 1, Regulates Amyloid- Oligomer Toxicity
- (2013) V. G. Ostapchenko et al. JOURNAL OF NEUROSCIENCE
- The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein
- (2013) Tiziana Sonati et al. NATURE
- Bidirectional NMDA receptor plasticity controls CA3 output and heterosynaptic metaplasticity
- (2013) David L Hunt et al. NATURE NEUROSCIENCE
- Suppression of eIF2α kinases alleviates Alzheimer's disease–related plasticity and memory deficits
- (2013) Tao Ma et al. NATURE NEUROSCIENCE
- Metabotropic Glutamate Receptor 5 Is a Coreceptor for Alzheimer Aβ Oligomer Bound to Cellular Prion Protein
- (2013) Ji Won Um et al. NEURON
- Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice
- (2013) J. A. Moreno et al. Science Translational Medicine
- Laminin-γ1 chain and stress inducible protein 1 synergistically mediate PrPC-dependent axonal growth via Ca2+mobilization in dorsal root ganglia neurons
- (2012) Tiago G. Santos et al. JOURNAL OF NEUROCHEMISTRY
- The Complex PrPc-Fyn Couples Human Oligomeric A with Pathological Tau Changes in Alzheimer's Disease
- (2012) M. Larson et al. JOURNAL OF NEUROSCIENCE
- Sustained translational repression by eIF2α-P mediates prion neurodegeneration
- (2012) Julie A. Moreno et al. NATURE
- Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons
- (2012) Ji Won Um et al. NATURE NEUROSCIENCE
- A neurotoxicity depends on interactions between copper ions, prion protein, and N-methyl-D-aspartate receptors
- (2012) H. You et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Prion protein facilitates uptake of zinc into neuronal cells
- (2012) Nicole T. Watt et al. Nature Communications
- Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons
- (2011) Marcus J. Calkins et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- The cellular prion protein mediates neurotoxic signalling of β-sheet-rich conformers independent of prion replication
- (2011) Ulrike K Resenberger et al. EMBO JOURNAL
- Neuritogenesis: the prion protein controls β1 integrin signaling activity
- (2011) Damien Loubet et al. FASEB JOURNAL
- Cellular prion protein is essential for oligomeric amyloid- -induced neuronal cell death
- (2011) W. Kudo et al. HUMAN MOLECULAR GENETICS
- α-Secretase-derived Fragment of Cellular Prion, N1, Protects against Monomeric and Oligomeric Amyloid β (Aβ)-associated Cell Death
- (2011) Marie-Victoire Guillot-Sestier et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Amyloid-β-induced Synapse Damage Is Mediated via Cross-linkage of Cellular Prion Proteins
- (2011) Clive Bate et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Amyloid-beta oligomers increase the localization of prion protein at the cell surface
- (2011) Fabiana A. Caetano et al. JOURNAL OF NEUROCHEMISTRY
- Alzheimer's Disease Brain-Derived Amyloid- -Mediated Inhibition of LTP In Vivo Is Prevented by Immunotargeting Cellular Prion Protein
- (2011) A. E. Barry et al. JOURNAL OF NEUROSCIENCE
- Therapeutic significance of NR2B-containing NMDA receptors and mGluR5 metabotropic glutamate receptors in mediating the synaptotoxic effects of β-amyloid oligomers on long-term potentiation (LTP) in murine hippocampal slices
- (2011) Gerhard Rammes et al. NEUROPHARMACOLOGY
- Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites
- (2011) Darragh B. Freir et al. Nature Communications
- Anti-PrPC monoclonal antibody infusion as a novel treatment for cognitive deficits in an alzheimer's disease model mouse
- (2010) Erika Chung et al. BMC NEUROSCIENCE
- Metabotropic glutamate receptors transduce signals for neurite outgrowth after binding of the prion protein to laminin γ1 chain
- (2010) Flavio H. Beraldo et al. FASEB JOURNAL
- Role of α7 Nicotinic Acetylcholine Receptor in Calcium Signaling Induced by Prion Protein Interaction with Stress-inducible Protein 1
- (2010) Flavio H. Beraldo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Memory Impairment in Transgenic Alzheimer Mice Requires Cellular Prion Protein
- (2010) D. A. Gimbel et al. JOURNAL OF NEUROSCIENCE
- Deleterious Effects of Amyloid β Oligomers Acting as an Extracellular Scaffold for mGluR5
- (2010) Marianne Renner et al. NEURON
- Prion protein interaction with stress-inducible protein 1 enhances neuronal protein synthesis via mTOR
- (2010) M. Roffe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphorylation-independent Regulation of Metabotropic Glutamate Receptor 5 Desensitization and Internalization by G Protein-coupled Receptor Kinase 2 in Neurons
- (2009) Fabiola M. Ribeiro et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Clathrin-independent internalization of normal cellular prion protein in neuroblastoma cells is associated with the Arf6 pathway
- (2009) Y.-S. Kang et al. JOURNAL OF CELL SCIENCE
- Regulation of Group I Metabotropic Glutamate Receptor Trafficking and Signaling by the Caveolar/Lipid Raft Pathway
- (2009) A. Francesconi et al. JOURNAL OF NEUROSCIENCE
- Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers
- (2009) Juha Laurén et al. NATURE
- Lipid Rafts and Clathrin Cooperate in the Internalization of PrPC in Epithelial FRT Cells
- (2009) Daniela Sarnataro et al. PLoS One
- Absence of the Cellular Prion Protein Exacerbates and Prolongs Neuroinflammation in Experimental Autoimmune Encephalomyelitis
- (2008) Shigeki Tsutsui et al. AMERICAN JOURNAL OF PATHOLOGY
- Endocytosis of Prion Protein Is Required for ERK1/2 Signaling Induced by Stress-Inducible Protein 1
- (2008) F. A. Caetano et al. JOURNAL OF NEUROSCIENCE
- Physiology of the Prion Protein
- (2008) Rafael Linden et al. PHYSIOLOGICAL REVIEWS
- Internalization of mammalian fluorescent cellular prion protein and N-terminal deletion mutants in living cells
- (2003) Kil S. Lee et al. JOURNAL OF NEUROCHEMISTRY
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