Male Subfertility Induced by Heterozygous Expression of Catalytically Inactive Glutathione Peroxidase 4 Is Rescuedin Vivoby Systemic Inactivation of theAlox15Gene

Expression of Inactive Glutathione Peroxidase 4 Leads to Embryonic Lethality, and Inactivation of the Alox15 Gene Does Not Rescue Such Knock-In Mice

(2015) Simone Hanna Brütsch et al.   ANTIOXIDANTS & REDOX SIGNALING

Mutagenesis of triad determinants of rat Alox15 alters the specificity of fatty acid and phospholipid oxygenation

(2015) Mária Pekárová et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors

(2015) O. Canli et al.   BLOOD

Structural and functional biology of arachidonic acid 15-lipoxygenase-1 (ALOX15)

(2015) Igor Ivanov et al.   GENE

Expression of a Catalytically Inactive Mutant Form of Glutathione Peroxidase 4 (Gpx4) Confers a Dominant-negative Effect in Male Fertility

(2015) Irina Ingold et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differences in ATP Generation Via Glycolysis and Oxidative Phosphorylation and Relationships with Sperm Motility in Mouse Species

(2015) Maximiliano Tourmente et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glutathione peroxidases as redox sensor proteins in plant cells

(2015) Gisele Passaia et al.   PLANT SCIENCE

Absence of Glutathione Peroxidase 4 Affects Tumor Angiogenesis through Increased 12/15-Lipoxygenase Activity

(2015) Manuela Schneider et al.   NEOPLASIA

Glutathione peroxidase 4 is reversibly induced by HCV to control lipid peroxidation and to increase virion infectivity

(2014) Charlène Brault et al.   GUT

Mutations in the enzyme glutathione peroxidase 4 cause Sedaghatian-type spondylometaphyseal dysplasia

(2014) Amanda C Smith et al.   JOURNAL OF MEDICAL GENETICS

An overview of mechanisms of redox signaling

(2014) Henry Jay Forman et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Free Radicals and Antioxidants: How to Reestablish Redox Homeostasis in Chronic Diseases?

(2013) V. Bocci et al.   CURRENT MEDICINAL CHEMISTRY

Systematic analysis of rat 12/15-lipoxygenase enzymes reveals critical role for spinal eLOX3 hepoxilin synthase activity in inflammatory hyperalgesia

(2013) Ann M. Gregus et al.   FASEB JOURNAL

Oxidative Stress in Cardiovascular Diseases and Obesity: Role of p66Shc and Protein Kinase C

(2013) Elena De Marchi et al.   Oxidative Medicine and Cellular Longevity

The Yin and Yang of redox regulation

(2013) Lars Folke Olsen et al.   REDOX REPORT

A Systematic Review of Oxidative Stress and Safety of Antioxidants in Diabetes: Focus on Islets and Their Defense

(2013) Udayakumar Karunakaran et al.   Diabetes & Metabolism Journal

Glutathione peroxidases

(2012) Regina Brigelius-Flohé et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Lipoxygenase and Leukotriene Pathways: Biochemistry, Biology, and Roles in Disease

(2011) Jesper Z. Haeggström et al.   CHEMICAL REVIEWS

Molecular enzymology of lipoxygenases

(2010) Igor Ivanov et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Altered epididymal sperm maturation and cytoplasmic droplet migration in subfertile male Alox15 mice

(2010) Kelly Moore et al.   CELL AND TISSUE RESEARCH

Bid-mediated mitochondrial damage is a key mechanism in glutamate-induced oxidative stress and AIF-dependent cell death in immortalized HT-22 hippocampal neurons

(2010) S Tobaben et al.   CELL DEATH AND DIFFERENTIATION

Defining the immunoreactive epitope for the monoclonal anti-human glutathione peroxidase-4 antibody anti-hGPx4 Mab63-1

(2010) Astrid Borchert et al.   IMMUNOLOGY LETTERS

12/15-lipoxygenase-derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases

(2010) M. Conrad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Depletion of Selenoprotein GPx4 in Spermatocytes Causes Male Infertility in Mice

(2009) Hirotaka Imai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peroxidase: A Term of Many Meanings

(2008) Leopold Flohé et al.   ANTIOXIDANTS & REDOX SIGNALING

Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death

(2008) Alexander Seiler et al.   Cell Metabolism