Activation of Short and Long Chain Fatty Acid Sensing Machinery in the Ileum Lowers Glucose Productionin Vivo

Resveratrol activates duodenal Sirt1 to reverse insulin resistance in rats through a neuronal network

(2015) Clémence D Côté et al.   NATURE MEDICINE

Metformin activates a duodenal Ampk–dependent pathway to lower hepatic glucose production in rats

(2015) Frank A Duca et al.   NATURE MEDICINE

Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults

(2014) Edward S Chambers et al.   GUT

Microbiota and diabetes: an evolving relationship

(2014) Herbert Tilg et al.   GUT

The short chain fatty acid propionate stimulates GLP-1 and PYY secretion via free fatty acid receptor 2 in rodents

(2014) A Psichas et al.   INTERNATIONAL JOURNAL OF OBESITY

Ileal brake activation: macronutrient-specific effects on eating behavior?

(2014) M van Avesaat et al.   INTERNATIONAL JOURNAL OF OBESITY

Hormonal Signaling in the Gut

(2014) Clémence D. Côté et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ileal Glucose Infusion Leads to Increased Insulin Sensitivity and Decreased Blood Glucose Levels in Wistar Rats

(2014) Vo Nguyen Trung et al.   JOURNAL OF INVESTIGATIVE SURGERY

Identification of the Porcine G Protein-Coupled Receptor 41 and 43 Genes and Their Expression Pattern in Different Tissues and Development Stages

(2014) Genlai Li et al.   PLoS One

The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism

(2014) Gary Frost et al.   Nature Communications

Identification and Characterization of GLP-1 Receptor-Expressing Cells Using a New Transgenic Mouse Model

(2013) P. Richards et al.   DIABETES

GPR41/FFAR3 and GPR43/FFAR2 as Cosensors for Short-Chain Fatty Acids in Enteroendocrine Cells vs FFAR3 in Enteric Neurons and FFAR2 in Enteric Leukocytes

(2013) Mark K. Nøhr et al.   ENDOCRINOLOGY

Conserved Shifts in the Gut Microbiota Due to Gastric Bypass Reduce Host Weight and Adiposity

(2013) A. P. Liou et al.   Science Translational Medicine

The human small intestinal microbiota is driven by rapid uptake and conversion of simple carbohydrates

(2012) Erwin G Zoetendal et al.   ISME Journal

Jejunal nutrient sensing is required for duodenal-jejunal bypass surgery to rapidly lower glucose concentrations in uncontrolled diabetes

(2012) Danna M Breen et al.   NATURE MEDICINE

Butyrate and Propionate Protect against Diet-Induced Obesity and Regulate Gut Hormones via Free Fatty Acid Receptor 3-Independent Mechanisms

(2012) Hua V. Lin et al.   PLoS One

The common hepatic branch of the vagus is not required to mediate the glycemic and food intake suppressive effects of glucagon-like-peptide-1

(2011) Matthew R. Hayes et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein-Coupled Receptor FFAR2

(2011) G. Tolhurst et al.   DIABETES

Essential Role for Protein Kinase Cζ in Oleic Acid-Induced Glucagon-Like Peptide-1 Secretionin Vivoin the Rat

(2011) Roman Iakoubov et al.   ENDOCRINOLOGY

Duodenal Mucosal Protein Kinase C-δ Regulates Glucose Production in Rats

(2011) Andrea Kokorovic et al.   GASTROENTEROLOGY

Density distribution of free fatty acid receptor 2 (FFA2)-expressing and GLP-1-producing enteroendocrine L cells in human and rat lower intestine, and increased cell numbers after ingestion of fructo-oligosaccharide

(2010) Izumi Kaji et al.   JOURNAL OF MOLECULAR HISTOLOGY

Glucagon-like peptide-1 inhibits voltage-gated potassium currents in mouse nodose ganglion neurons

(2010) g. g. gaisano et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Electrical stimulation of the isolated rat intestine in the presence of nutrient stimulus enhances glucagon-like peptide-1 release

(2010) Ann Schwartz et al.   PHYSIOLOGICAL MEASUREMENT

Intestinal Cholecystokinin Controls Glucose Production through a Neuronal Network

(2009) Grace W.C. Cheung et al.   Cell Metabolism

Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice

(2009) Z. Gao et al.   DIABETES

Prebiotic oligosaccharides change the concentrations of short-chain fatty acids and the microbial population of mouse bowel

(2009) Xiao-dong Pan et al.   Journal of Zhejiang University-SCIENCE B

Anatomical Profiling of G Protein-Coupled Receptor Expression

(2008) Jean B. Regard et al.   CELL

Upper intestinal lipids trigger a gut–brain–liver axis to regulate glucose production

(2008) Penny Y. T. Wang et al.   NATURE