Genetic Variations in the Human G Protein-coupled Receptor Class C, Group 6, Member A (GPRC6A) Control Cell Surface Expression and Function

L-arginine promotes gut hormone release and reduces food intake in rodents

(2016) A. Alamshah et al.   DIABETES OBESITY & METABOLISM

Murine GPRC6A Mediates Cellular Responses to L-Amino Acids, but Not Osteocalcin Variants

(2016) Patricia Rueda et al.   PLoS One

N-glycosylation and disulfide bonding affects GPRC6A receptor expression, function, and dimerization

(2015) Lenea Nørskov-Lauritsen et al.   FEBS LETTERS

GPRC6a is not required for the effects of a high-protein diet on body weight in mice

(2015) James S. Kinsey-Jones et al.   Obesity

Generic GPCR residue numbers – aligning topology maps while minding the gaps

(2015) Vignir Isberg et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The experimental power of FR900359 to study Gq-regulated biological processes

(2015) Ramona Schrage et al.   Nature Communications

Evaluation of a target region capture sequencing platform using monogenic diabetes as a study-model

(2014) Rui Gao et al.   BMC GENETICS

The GPCR, class C, group 6, subtype A (GPRC6A) receptor: from cloning to physiological function

(2013) C Clemmensen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Osteocalcin regulates murine and human fertility through a pancreas-bone-testis axis

(2013) Franck Oury et al.   JOURNAL OF CLINICAL INVESTIGATION

Increased susceptibility to diet-induced obesity in GPRC6A receptor knockout mice

(2013) Christoffer Clemmensen et al.   JOURNAL OF ENDOCRINOLOGY

Enhanced voluntary wheel running in GPRC6A receptor knockout mice

(2013) Christoffer Clemmensen et al.   PHYSIOLOGY & BEHAVIOR

The l-α-amino acid receptor GPRC6A is expressed in the islets of Langerhans but is not involved in l-arginine-induced insulin release

(2012) Sanela Smajilovic et al.   AMINO ACIDS

GPRC6A Mediates the Effects ofl-Arginine on Insulin Secretion in Mouse Pancreatic Islets

(2012) Min Pi et al.   ENDOCRINOLOGY

Multiligand Specificity and Wide Tissue Expression of GPRC6A Reveals New Endocrine Networks

(2012) Min Pi et al.   ENDOCRINOLOGY

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors

(2012) Manuela Rossol et al.   Nature Communications

Regulation of GPCR activity, trafficking and localization by GPCR-interacting proteins

(2011) Ana C Magalhaes et al.   BRITISH JOURNAL OF PHARMACOLOGY

Endocrine Regulation of Male Fertility by the Skeleton

(2011) Franck Oury et al.   CELL

Non-canonical signaling and localizations of heterotrimeric G proteins

(2011) Thamara Hewavitharana et al.   CELLULAR SIGNALLING

GPRC6A mediates responses to osteocalcin in β-cells in vitro and pancreas in vivo

(2011) Min Pi et al.   JOURNAL OF BONE AND MINERAL RESEARCH

GPRC6A regulates prostate cancer progression

(2011) Min Pi et al.   PROSTATE

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

GPRC6A Mediates the Non-genomic Effects of Steroids

(2010) Min Pi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular determinants of non-competitive antagonist binding to the mouse GPRC6A receptor

(2009) Helene Faure et al.   CELL CALCIUM

No evidence for a bone phenotype in GPRC6A knockout mice under normal physiological conditions

(2008) Petrine Wellendorph et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

GPRC6A Null Mice Exhibit Osteopenia, Feminization and Metabolic Syndrome

(2008) Min Pi et al.   PLoS One