Stabilization of Nucleotide Binding Domain Dimers Rescues ABCC6 Mutants Associated with Pseudoxanthoma Elasticum

Thermal stability of purified and reconstituted CFTR in a locked open channel conformation

(2015) Luba A. Aleksandrov et al.   PROTEIN EXPRESSION AND PURIFICATION

ABCC6–Mediated ATP Secretion by the Liver Is the Main Source of the Mineralization Inhibitor Inorganic Pyrophosphate in the Systemic Circulation—Brief Report

(2014) Robert S. Jansen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cystic fibrosis genetics: from molecular understanding to clinical application

(2014) Garry R. Cutting   NATURE REVIEWS GENETICS

SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information

(2014) Marco Biasini et al.   NUCLEIC ACIDS RESEARCH

Regulation of ABCC6 Trafficking and Stability by a Conserved C-terminal PDZ-Like Sequence

(2014) Peng Xue et al.   PLoS One

Molecular Docking Simulations Provide Insights in the Substrate Binding Sites and Possible Substrates of the ABCC6 Transporter

(2014) Mohammad Jakir Hosen et al.   PLoS One

Pseudoxanthoma elasticum: diagnostic features, classification and treatment options

(2014) Jouni Uitto et al.   Expert Opinion on Orphan Drugs

Control of cystic fibrosis transmembrane conductance regulator membrane trafficking: not just from the endoplasmic reticulum to the Golgi

(2013) Carlos M. Farinha et al.   FEBS Journal

Analysis of Pseudoxanthoma Elasticum–Causing Missense Mutants of ABCC6 In Vivo ; Pharmacological Correction of the Mislocalized Proteins

(2013) Viola Pomozi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

ABCC6 prevents ectopic mineralization seen in pseudoxanthoma elasticum by inducing cellular nucleotide release

(2013) R. S. Jansen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states

(2013) C. A. Shintre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Requirements for Efficient Correction of ΔF508 CFTR Revealed by Analyses of Evolved Sequences

(2012) Juan L. Mendoza et al.   CELL

ABCMdb: A database for the comparative analysis of protein mutations in ABC transporters, and a potential framework for a general application

(2012) Gergely Gyimesi et al.   HUMAN MUTATION

Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans

(2012) Mi Sun Jin et al.   NATURE

Mammalian multidrug-resistance proteins (MRPs)

(2011) Andrew J. Slot et al.   Essays in Biochemistry

N-terminal transmembrane domain of SUR1 controls gating of Kir6.2 by modulating channel sensitivity to PIP2

(2011) Emily B. Pratt et al.   JOURNAL OF GENERAL PHYSIOLOGY

Bortezomib suppresses function and survival of plasmacytoid dendritic cells by targeting intracellular trafficking of Toll-like receptors and endoplasmic reticulum homeostasis

(2010) M. Hirai et al.   BLOOD

Restoration of domain folding and interdomain assembly by second-site suppressors of the ΔF508 mutation in CFTR

(2010) Lihua He et al.   FASEB JOURNAL

The Cystic Fibrosis-causing Mutation ΔF508 Affects Multiple Steps in Cystic Fibrosis Transmembrane Conductance Regulator Biogenesis

(2010) Patrick H. Thibodeau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thermal unfolding studies show the disease causing F508del mutation in CFTR thermodynamically destabilizes nucleotide-binding domain 1

(2010) Irina Protasevich et al.   PROTEIN SCIENCE

Automated minimization of steric clashes in protein structures

(2010) Srinivas Ramachandran et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Clustering of disease-causing mutations on the domain–domain interfaces of ABCC6

(2009) Krisztina Fülöp et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Solubilizing Mutations Used to Crystallize One CFTR Domain Attenuate the Trafficking and Channel Defects Caused by the Major Cystic Fibrosis Mutation

(2008) Luísa S. Pissarra et al.   CHEMISTRY & BIOLOGY

Pseudoxanthoma Elasticum Is a Metabolic Disease

(2008) Qiujie Jiang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY