ABCC6–Mediated ATP Secretion by the Liver Is the Main Source of the Mineralization Inhibitor Inorganic Pyrophosphate in the Systemic Circulation—Brief Report

Fibroblasts from patients affected by Pseudoxanthoma elasticum exhibit an altered PPi metabolism and are more responsive to pro-calcifying stimuli

(2014) Federica Boraldi et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Changes in Dermal Fibroblasts from Abcc6 −/− Mice Are Present before and after the Onset of Ectopic Tissue Mineralization

(2014) Federica Boraldi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Vascular calcification is dependent on plasma levels of pyrophosphate

(2014) Koba A. Lomashvili et al.   KIDNEY INTERNATIONAL

Pseudoxanthoma Elasticum: Progress in Research Toward Treatment: Summary of the 2012 PXE International Research Meeting

(2013) Jouni Uitto et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

ABCC6 prevents ectopic mineralization seen in pseudoxanthoma elasticum by inducing cellular nucleotide release

(2013) R. S. Jansen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vesicular and conductive mechanisms of nucleotide release

(2012) Eduardo R. Lazarowski   Purinergic Signalling

Generalized arterial calcification of infancy and pseudoxanthoma elasticum: two sides of the same coin

(2012) Yvonne Nitschke et al.   Frontiers in Genetics

Genetics in Arterial Calcification

(2011) Frank Rutsch et al.   CIRCULATION RESEARCH

Local release of ATP into the arterial inflow and venous drainage of human skeletal muscle: insight from ATP determination with the intravascular microdialysis technique

(2011) Stefan P. Mortensen et al.   JOURNAL OF PHYSIOLOGY-LONDON

NT5EMutations and Arterial Calcifications

(2011) Cynthia St. Hilaire et al.   NEW ENGLAND JOURNAL OF MEDICINE

Parabiotic Heterogenetic Pairing of Abcc6−/−/Rag1−/− Mice and Their Wild-Type Counterparts Halts Ectopic Mineralization in a Murine Model of Pseudoxanthoma Elasticum

(2010) Qiujie Jiang et al.   AMERICAN JOURNAL OF PATHOLOGY

Treatment with pyrophosphate inhibits uremic vascular calcification

(2010) W Charles O'Neill et al.   KIDNEY INTERNATIONAL

Hypophosphatemia, Hyperphosphaturia, and Bisphosphonate Treatment Are Associated With Survival Beyond Infancy in Generalized Arterial Calcification of Infancy

(2008) Frank Rutsch et al.   Circulation-Cardiovascular Genetics