Emodin Bidirectionally Modulates Macrophage Polarization and Epigenetically Regulates Macrophage Memory

Emodin Protects Against Concanavalin A-Induced Hepatitis in Mice Through Inhibiting Activation of the p38 MAPK-NF-κB Signaling Pathway

(2015) Jihua Xue et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Human papillomavirus status and gene expression profiles of oropharyngeal and oral cancers from European American and African American patients

(2015) Swati Tomar et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Alternatively activated macrophages promote pancreatic fibrosis in chronic pancreatitis

(2015) Jing Xue et al.   Nature Communications

Development of phenylboronic acid-functionalized nanoparticles for emodin delivery

(2015) Bo Wang et al.   Journal of Materials Chemistry B

Downregulation of tumor necrosis factor and other proinflammatory biomarkers by polyphenols

(2014) Subash C. Gupta et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Emodin suppresses pulmonary metastasis of breast cancer accompanied with decreased macrophage recruitment and M2 polarization in the lungs

(2014) Xuemei Jia et al.   BREAST CANCER RESEARCH AND TREATMENT

Protective effect of emodin against airway inflammation in the ovalbumin-induced mouse model

(2014) Tan Wang et al.   Chinese Journal of Integrative Medicine

Trained Immunity or Tolerance: Opposing Functional Programs Induced in Human Monocytes after Engagement of Various Pattern Recognition Receptors

(2014) Daniela C. Ifrim et al.   Clinical and Vaccine Immunology

Emodin attenuates systemic and liver inflammation in hyperlipidemic mice administrated with lipopolysaccharides

(2014) Xuemei Jia et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Macrophages, Immunity, and Metabolic Disease

(2014) Joanne C. McNelis et al.   IMMUNITY

Emodin inhibits LPS-induced inflammatory response by activating PPAR-γ in mouse mammary epithelial cells

(2014) Zhengtao Yang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Macrophage CD14 expression in human carotid plaques is associated with complicated lesions, correlates with thrombosis, and is reduced by angiotensin receptor blocker treatment

(2014) Cecilia Hermansson et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Emodin Ameliorates LPS-Induced Acute Lung Injury, Involving the Inactivation of NF-κB in Mice

(2014) Min Xiao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity

(2014) S. Saeed et al.   SCIENCE

Myeloid cell dysfunction and the pathogenesis of the diabetic chronic wound

(2014) Kate Wicks et al.   SEMINARS IN IMMUNOLOGY

Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer

(2013) Deepti Shrimali et al.   CANCER LETTERS

Clinical significance of macrophage heterogeneity in human malignant tumors

(2013) Yoshihiro Komohara et al.   CANCER SCIENCE

Macrophage polarization and function with emphasis on the evolving roles of coordinated regulation of cellular signaling pathways

(2013) Dexi Zhou et al.   CELLULAR SIGNALLING

Monocyte and Macrophage Heterogeneity in the Heart

(2013) Matthias Nahrendorf et al.   CIRCULATION RESEARCH

Synergistic Activation of Inflammatory Cytokine Genes by Interferon-γ-Induced Chromatin Remodeling and Toll-like Receptor Signaling

(2013) Yu Qiao et al.   IMMUNITY

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

Anti-Inflammatory Therapy in Chronic Disease: Challenges and Opportunities

(2013) I. Tabas et al.   SCIENCE

Curcumin in inflammatory diseases

(2012) Adeeb Shehzad et al.   BIOFACTORS

Effects of an anthraquinone derivative from Rheum officinale Baill, emodin, on airway responses in a murine model of asthma

(2012) Xiao Chu et al.   FOOD AND CHEMICAL TOXICOLOGY

Molecular Mechanism Responsible for the Priming of Macrophage Activation

(2012) Hui Deng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Harnessing monocyte-derived macrophages to control central nervous system pathologies: no longer ‘if’ but ‘how’

(2012) Ravid Shechter et al.   JOURNAL OF PATHOLOGY

Epigenetic regulation of macrophage polarization and function

(2012) Lionel B. Ivashkiv   TRENDS IN IMMUNOLOGY

Emodin Prolongs Recipient Survival Time After Orthotopic Liver Transplantation in Rats by Polarizing the Th1/Th2 Paradigm to Th2

(2011) Hongfei Tong et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

A CK2-dependent mechanism for activation of the JAK-STAT signaling pathway

(2011) Y. Zheng et al.   BLOOD

Trained Immunity: A Memory for Innate Host Defense

(2011) Mihai G. Netea et al.   Cell Host & Microbe

Subcutaneous Adipose Tissue Macrophage Infiltration Is Associated With Hepatic and Visceral Fat Deposition, Hyperinsulinemia, and Stimulation of NF-κB Stress Pathway

(2011) Kim-Anne Lê et al.   DIABETES

Emodin Induces Apoptotic Death in Murine Myelomonocytic Leukemia WEHI-3 CellsIn Vitroand Enhances Phagocytosis in Leukemia MiceIn Vivo

(2011) Yuan-Chang Chang et al.   Evidence-based Complementary and Alternative Medicine

Characterization of Sparstolonin B, a Chinese Herb-derived Compound, as a Selective Toll-like Receptor Antagonist with Potent Anti-inflammatory Properties

(2011) Qiaoli Liang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Steady-state pharmacokinetics and tissue distribution of anthraquinones of Rhei Rhizoma in rats

(2011) Chi-Sheng Shia et al.   JOURNAL OF ETHNOPHARMACOLOGY

Suppressor of cytokine signaling (SOCS)1 is a key determinant of differential macrophage activation and function

(2011) Claire S. Whyte et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Biochemical markers of ongoing joint damage in rheumatoid arthritis - current and future applications, limitations and opportunities

(2011) Morten A Karsdal et al.   ARTHRITIS RESEARCH & THERAPY

Control of Macrophage Activation and Function by PPARs

(2010) Ajay Chawla   CIRCULATION RESEARCH

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Interleukin-4 induced interferon regulatory factor (Irf) 4 participates in the regulation of alternative macrophage priming

(2010) Carol El Chartouni et al.   IMMUNOBIOLOGY

Immunosuppressive and anti-inflammatory activities of sinomenine

(2010) Quanxing Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection

(2010) Takashi Satoh et al.   NATURE IMMUNOLOGY

Resorufin: a lead for a new protein kinase CK2 inhibitor

(2009) Iben Skjøth Sandholt et al.   ANTI-CANCER DRUGS

Epigenetic regulation of the alternatively activated macrophage phenotype

(2009) M. Ishii et al.   BLOOD

p21waf1/CIP1, a CDK inhibitor and a negative feedback system that controls macrophage activation

(2009) Jorge Lloberas et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Inflammation: Gearing the journey to cancer

(2008) J KUNDU et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH