Human Central Nervous System (CNS) ApoE Isoforms Are Increased by Age, Differentially Altered by Amyloidosis, and Relative Amounts Reversed in the CNS Compared with Plasma

Following Activation of the Amyloid Cascade, Apolipoprotein E4 Drives the in vivo Oligomerization of Amyloid-β Resulting in Neurodegeneration

(2017) Haim Belinson et al.   JOURNAL OF ALZHEIMERS DISEASE

Murine versus human apolipoprotein E4: differential facilitation of and co-localization in cerebral amyloid angiopathy and amyloid plaques in APP transgenic mouse models

(2015) Fan Liao et al.   Acta Neuropathologica Communications

CSF Apo-E levels associate with cognitive decline and MRI changes

(2014) Jon B. Toledo et al.   ACTA NEUROPATHOLOGICA

Total apolipoprotein E levels and specific isoform composition in cerebrospinal fluid and plasma from Alzheimer’s disease patients and controls

(2014) Eduardo Martínez-Morillo et al.   ACTA NEUROPATHOLOGICA

Apolipoprotein E in Alzheimer's Disease: An Update

(2014) Jin-Tai Yu et al.   Annual Review of Neuroscience

Influence ofAPOEgenotype and the presence of Alzheimer's pathology on synaptic membrane lipids of human brains

(2014) Naoto Oikawa et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Assessment of Peptide Chemical Modifications on the Development of an Accurate and Precise Multiplex Selected Reaction Monitoring Assay for Apolipoprotein E Isoforms

(2014) Eduardo Martínez-Morillo et al.   JOURNAL OF PROTEOME RESEARCH

Apolipoprotein E, amyloid-beta, and neuroinflammation in Alzheimer’s disease

(2014) Evan Dorey et al.   Neuroscience Bulletin

Human APOE genotype affects intraneuronal A 1-42 accumulation in a lentiviral gene transfer model

(2013) W. Zhao et al.   HUMAN MOLECULAR GENETICS

ApoE influences amyloid-  (A ) clearance despite minimal apoE/A  association in physiological conditions

(2013) P. B. Verghese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased in Vivo Amyloid- 42 Production, Exchange, and Loss in Presenilin Mutation Carriers

(2013) R. Potter et al.   Science Translational Medicine

National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

(2012) Bradley T. Hyman et al.   Alzheimers & Dementia

Cerebrospinal fluid APOE levels: an endophenotype for genetic studies for Alzheimer's disease

(2012) Carlos Cruchaga et al.   HUMAN MOLECULAR GENETICS

Low-density Lipoprotein Receptor Represents an Apolipoprotein E-independent Pathway of Aβ Uptake and Degradation by Astrocytes

(2012) Jacob M. Basak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Total ApoE and ApoE4 Isoform Assays in an Alzheimer's Disease Case-control Study by Targeted Mass Spectrometry (n= 669): A Pilot Assay for Methionine-containing Proteotypic Peptides

(2012) Romain Simon et al.   MOLECULAR & CELLULAR PROTEOMICS

Apolipoprotein E Sets the Stage: Response to Injury Triggers Neuropathology

(2012) Robert W. Mahley et al.   NEURON

Effects of Age and Amyloid Deposition on Aβ Dynamics in the Human Central Nervous System

(2011) Yafei Huang   ARCHIVES OF NEUROLOGY

Core features of frontotemporal dementia recapitulated in progranulin knockout mice

(2011) N. Ghoshal et al.   NEUROBIOLOGY OF DISEASE

GFAP in health and disease

(2011) J. Middeldorp et al.   PROGRESS IN NEUROBIOLOGY

Human apoE Isoforms Differentially Regulate Brain Amyloid-  Peptide Clearance

(2011) J. M. Castellano et al.   Science Translational Medicine

Accumulation of intraneuronal Aβ correlates with ApoE4 genotype

(2010) Ditte Z. Christensen et al.   ACTA NEUROPATHOLOGICA

Autopsy consent, brain collection, and standardized neuropathologic assessment of ADNI participants: The essential role of the Neuropathology Core

(2010) Nigel J. Cairns et al.   Alzheimers & Dementia

Spatial Memory Consolidation is Associated with Induction of Several Lysine-Acetyltransferase (Histone Acetyltransferase) Expression Levels and H2B/H4 Acetylation-Dependent Transcriptional Events in the Rat Hippocampus

(2010) Olivier Bousiges et al.   NEUROPSYCHOPHARMACOLOGY

Method for the simultaneous quantitation of apolipoprotein E isoforms using tandem mass spectrometry

(2009) Kristin R. Wildsmith et al.   ANALYTICAL BIOCHEMISTRY

APOEpredicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging

(2009) John C. Morris et al.   ANNALS OF NEUROLOGY

The fundamental flaws of immunoassays and potential solutions using tandem mass spectrometry

(2009) Andrew N. Hoofnagle et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Hippocampal and Cognitive Aging across the Lifespan: A Bioenergetic Shift Precedes and Increased Cholesterol Trafficking Parallels Memory Impairment

(2009) I. Kadish et al.   JOURNAL OF NEUROSCIENCE

Impact of Apolipoprotein E (ApoE) Polymorphism on Brain ApoE Levels

(2008) D. R. Riddell et al.   JOURNAL OF NEUROSCIENCE

ApoE Promotes the Proteolytic Degradation of Aβ

(2008) Qingguang Jiang et al.   NEURON