Total ApoE and ApoE4 Isoform Assays in an Alzheimer's Disease Case-control Study by Targeted Mass Spectrometry (n= 669): A Pilot Assay for Methionine-containing Proteotypic Peptides

Multiple SNPs Within and Surrounding the Apolipoprotein E Gene Influence Cerebrospinal Fluid Apolipoprotein E Protein Levels

(2017) Lynn M. Bekris et al.   JOURNAL OF ALZHEIMERS DISEASE

Multiple-Reaction Monitoring-Mass Spectrometric Assays Can Accurately Measure the Relative Protein Abundance in Complex Mixtures

(2012) A. N. Hoofnagle et al.   CLINICAL CHEMISTRY

ApoE-Directed Therapeutics Rapidly Clear  -Amyloid and Reverse Deficits in AD Mouse Models

(2012) P. E. Cramer et al.   SCIENCE

Genetics of Alzheimer's disease: new evidences for an old hypothesis?

(2011) Jean-Charles Lambert et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Selected reaction monitoring applied to proteomics

(2011) Sebastien Gallien et al.   JOURNAL OF MASS SPECTROMETRY

Evaluation of Different Multidimensional LC–MS/MS Pipelines for Isobaric Tags for Relative and Absolute Quantitation (iTRAQ)-Based Proteomic Analysis of Potato Tubers in Response to Cold Storage

(2011) Yong Yang et al.   JOURNAL OF PROTEOME RESEARCH

Apolipoprotein E in Alzheimer's disease and other neurological disorders

(2011) Philip B Verghese et al.   LANCET NEUROLOGY

A pipeline that integrates the discovery and verification of plasma protein biomarkers reveals candidate markers for cardiovascular disease

(2011) Terri A Addona et al.   NATURE BIOTECHNOLOGY

A targeted proteomics–based pipeline for verification of biomarkers in plasma

(2011) Jeffrey R Whiteaker et al.   NATURE BIOTECHNOLOGY

Plasma apolipoprotein E and Alzheimer disease risk: The AIBL study of aging

(2011) V. B. Gupta et al.   NEUROLOGY

Mass spectrometric immunoassay for quantitative determination of transthyretin and its variants

(2011) Olgica Trenchevska et al.   PROTEOMICS

Systematic quantification of peptides/proteins in urine using selected reaction monitoring

(2011) Nathalie Selevsek et al.   PROTEOMICS

A rapid method for cross-species quantitation of apolipoproteins A1, B48 and B100 in plasma by ultra-performance liquid chromatography/tandem mass spectrometry

(2011) Michael E. Lassman et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Simultaneous Quantification of Apolipoprotein A-I and Apolipoprotein B by Liquid-Chromatography-Multiple- Reaction-Monitoring Mass Spectrometry

(2010) S. A. Agger et al.   CLINICAL CHEMISTRY

Platform for Establishing Interlaboratory Reproducibility of Selected Reaction Monitoring-Based Mass Spectrometry Peptide Assays

(2010) A. Prakash et al.   JOURNAL OF PROTEOME RESEARCH

A Quantitative Study of the Effects of Chaotropic Agents, Surfactants, and Solvents on the Digestion Efficiency of Human Plasma Proteins by Trypsin

(2010) Jennifer L. Proc et al.   JOURNAL OF PROTEOME RESEARCH

On the Development of Plasma Protein Biomarkers

(2010) Silvia Surinova et al.   JOURNAL OF PROTEOME RESEARCH

Tyrosine−Lipid Peroxide Adducts from Radical Termination: Para Coupling and Intramolecular Diels−Alder Cyclization

(2010) Roman Shchepin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Options and considerations when selecting a quantitative proteomics strategy

(2010) Bruno Domon et al.   NATURE BIOTECHNOLOGY

Hippocampal atrophy rates and CSF biomarkers in elderly APOE2 normal subjects

(2010) G. C. Chiang et al.   NEUROLOGY

Method for the simultaneous quantitation of apolipoprotein E isoforms using tandem mass spectrometry

(2009) Kristin R. Wildsmith et al.   ANALYTICAL BIOCHEMISTRY

APOEpredicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging

(2009) John C. Morris et al.   ANNALS OF NEUROLOGY

The Bottleneck in the Cancer Biomarker Pipeline and Protein Quantification through Mass Spectrometry-Based Approaches: Current Strategies for Candidate Verification

(2009) S. Makawita et al.   CLINICAL CHEMISTRY

Developing Multiplexed Assays for Troponin I and Interleukin-33 in Plasma by Peptide Immunoaffinity Enrichment and Targeted Mass Spectrometry

(2009) E. Kuhn et al.   CLINICAL CHEMISTRY

Perspectives of targeted mass spectrometry for protein biomarker verification

(2009) Ruth Hüttenhain et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Human APOE Isoform-Dependent Effects on Brain  -Amyloid Levels in PDAPP Transgenic Mice

(2009) K. R. Bales et al.   JOURNAL OF NEUROSCIENCE

Interlaboratory Study Characterizing a Yeast Performance Standard for Benchmarking LC-MS Platform Performance

(2009) Amanda G. Paulovich et al.   MOLECULAR & CELLULAR PROTEOMICS

Multiple Reaction Monitoring-based, Multiplexed, Absolute Quantitation of 45 Proteins in Human Plasma

(2009) Michael A. Kuzyk et al.   MOLECULAR & CELLULAR PROTEOMICS

Quantification of Cardiovascular Biomarkers in Patient Plasma by Targeted Mass Spectrometry and Stable Isotope Dilution

(2009) Hasmik Keshishian et al.   MOLECULAR & CELLULAR PROTEOMICS

Multi-site assessment of the precision and reproducibility of multiple reaction monitoring–based measurements of proteins in plasma

(2009) Terri A Addona et al.   NATURE BIOTECHNOLOGY

Fibrillar amyloid-  burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease

(2009) E. M. Reiman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein Quantitation through Targeted Mass Spectrometry: The Way Out of Biomarker Purgatory?

(2008) S. A. Carr et al.   CLINICAL CHEMISTRY

Quantification of Thyroglobulin, a Low-Abundance Serum Protein, by Immunoaffinity Peptide Enrichment and Tandem Mass Spectrometry

(2008) A. N. Hoofnagle et al.   CLINICAL CHEMISTRY

Impact of Apolipoprotein E (ApoE) Polymorphism on Brain ApoE Levels

(2008) D. R. Riddell et al.   JOURNAL OF NEUROSCIENCE

Mass Spectrometry Based Targeted Protein Quantification: Methods and Applications

(2008) Sheng Pan et al.   JOURNAL OF PROTEOME RESEARCH

Clinical Quantitation of Prostate-specific Antigen Biomarker in the Low Nanogram/Milliliter Range by Conventional Bore Liquid Chromatography-Tandem Mass Spectrometry (Multiple Reaction Monitoring) Coupling and Correlation with ELISA Tests

(2008) Tanguy Fortin et al.   MOLECULAR & CELLULAR PROTEOMICS

Targeted proteomic strategy for clinical biomarker discovery

(2008) Ralph Schiess et al.   Molecular Oncology

Selected reaction monitoring for quantitative proteomics: a tutorial

(2008) Vinzenz Lange et al.   Molecular Systems Biology

The interface between biomarker discovery and clinical validation: The tar pit of the protein biomarker pipeline

(2008) Amanda G. Paulovich et al.   Proteomics Clinical Applications