In vivo partial cellular reprogramming enhances liver plasticity and regeneration

Proliferation tracing reveals regional hepatocyte generation in liver homeostasis and repair

(2021) Lingjuan He et al.   SCIENCE

Liver homeostasis is maintained by midlobular zone 2 hepatocytes

(2021) Yonglong Wei et al.   SCIENCE

Reversible reprogramming of cardiomyocytes to a fetal state drives heart regeneration in mice

(2021) Yanpu Chen et al.   SCIENCE

In vivo partial reprogramming of myofibers promotes muscle regeneration by remodeling the stem cell niche

(2021) Chao Wang et al.   Nature Communications

AFP promotes HCC progression by suppressing the HuR-mediated Fas/FADD apoptotic pathway

(2020) Tianke Chen et al.   Cell Death & Disease

Reprogramming to recover youthful epigenetic information and restore vision

(2020) Yuancheng Lu et al.   NATURE

Liver Regeneration after Acetaminophen Hepatotoxicity: Mechanisms and Therapeutic Opportunities

(2019) Bharat Bhushan et al.   AMERICAN JOURNAL OF PATHOLOGY

Reduction of Fibrosis and Scar Formation by Partial Reprogramming In Vivo

(2018) Markus C. Doeser et al.   STEM CELLS

In vivo reprogramming drives Kras-induced cancer development

(2018) Hirofumi Shibata et al.   Nature Communications

An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues

(2017) M Ryan Corces et al.   NATURE METHODS

TOP2 synergizes with BAF chromatin remodeling for both resolution and formation of facultative heterochromatin

(2017) Erik L Miller et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Integration of CpG-free DNA induces de novo methylation of CpG islands in pluripotent stem cells

(2017) Yuta Takahashi et al.   SCIENCE

TOP2 synergizes with BAF chromatin remodeling for both resolution and formation of facultative heterochromatin

(2017) Erik L Miller et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming

(2016) Alejandro Ocampo et al.   CELL

Skeletal muscle dedifferentiation during salamander limb regeneration

(2016) Heng Wang et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Chromatin Scanning by Dynamic Binding of Pioneer Factors

(2016) Kenneth S. Zaret et al.   MOLECULAR CELL

The Pioneer Transcription Factor FoxA Maintains an Accessible Nucleosome Configuration at Enhancers for Tissue-Specific Gene Activation

(2016) Makiko Iwafuchi-Doi et al.   MOLECULAR CELL

A developmentally regulated switch from stem cells to dedifferentiation for limb muscle regeneration in newts

(2016) Hibiki Vincent Tanaka et al.   Nature Communications

Dppa3 expression is critical for generation of fully reprogrammed iPS cells and maintenance of Dlk1-Dio3 imprinting

(2015) Xingbo Xu et al.   Nature Communications

Premature Termination of Reprogramming In Vivo Leads to Cancer Development through Altered Epigenetic Regulation

(2014) Kotaro Ohnishi et al.   CELL

Reprogramming in vivo produces teratomas and iPS cells with totipotency features

(2013) María Abad et al.   NATURE

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

(2013) Jason D Buenrostro et al.   NATURE METHODS

Gene regulation and priming by topoisomerase IIα in embryonic stem cells

(2013) Sudhir Thakurela et al.   Nature Communications

Salamanders and fish can regenerate lost structures - why can't we?

(2012) Hans-Georg Simon   BMC BIOLOGY

Transcription Factor AP1 Potentiates Chromatin Accessibility and Glucocorticoid Receptor Binding

(2011) Simon C. Biddie et al.   MOLECULAR CELL

Germ-layer and lineage-restricted stem/progenitors regenerate the mouse digit tip

(2011) Yuval Rinkevich et al.   NATURE

A Myc Network Accounts for Similarities between Embryonic Stem and Cancer Cell Transcription Programs

(2010) Jonghwan Kim et al.   CELL

Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation

(2010) Chris Jopling et al.   NATURE

The alpha-fetoprotein enhancer region activates the albumin and alpha-fetoprotein promoters during liver development

(2009) Lin Jin et al.   DEVELOPMENTAL BIOLOGY

Linking the p53 tumour suppressor pathway to somatic cell reprogramming

(2009) Teruhisa Kawamura et al.   NATURE

Suppression of induced pluripotent stem cell generation by the p53–p21 pathway

(2009) Hyenjong Hong et al.   NATURE

Single-gene transgenic mouse strains for reprogramming adult somatic cells

(2009) Bryce W Carey et al.   NATURE METHODS