Use of Noncanonical Tyrosine Analogues to Probe Control of Radical Intermediates during Endoperoxide Installation by Verruculogen Synthase (FtmOx1)

Molecular insights into the endoperoxide formation by Fe(II)/α-KG-dependent oxygenase NvfI

(2021) Takahiro Mori et al.   Nature Communications

Structural Insight into the Catalytic Mechanism of the Endoperoxide Synthase FtmOx1

(2021) Lian Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structural and Chemical Biology of the Interaction of Cyclooxygenase with Substrates and Non-Steroidal Anti-Inflammatory Drugs

(2020) Carol A. Rouzer et al.   CHEMICAL REVIEWS

Hydrogen Donation but not Abstraction by a Tyrosine (Y68) During Endoperoxide Installation by Verruculogen Synthase (FtmOx1)

(2019) Noah P. Dunham et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Protein’s Role in Substrate Positioning and Reactivity for Biosynthetic Enzyme Complexes: The Case of SyrB2/SyrB1

(2019) Rimsha Mehmood et al.   ACS Catalysis

Time-Resolved Infrared and Visible Spectroscopy on Cryptochrome aCRY: Basis for Red Light Reception

(2019) Sabine Oldemeyer et al.   BIOPHYSICAL JOURNAL

Evidence for Modulation of Oxygen Rebound Rate in Control of Outcome by Iron(II)- and 2-Oxoglutarate-Dependent Oxygenases

(2019) Juan Pan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalysis by the Non-Heme Iron(II) Histone Demethylase PHF8 Involves Iron Center Rearrangement and Conformational Modulation of Substrate Orientation

(2019) Shobhit S. Chaturvedi et al.   ACS Catalysis

Playing with the Molecules of Life

(2018) Douglas D. Young et al.   ACS Chemical Biology

Novofumigatonin biosynthesis involves a non-heme iron-dependent endoperoxide isomerase for orthoester formation

(2018) Yudai Matsuda et al.   Nature Communications

Formal Reduction Potentials of Difluorotyrosine and Trifluorotyrosine Protein Residues: Defining the Thermodynamics of Multistep Radical Transfer

(2017) Kanchana R. Ravichandran et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Insights into the unprecedented epoxidation mechanism of fumitremorgin B endoperoxidase (FtmOx1) from Aspergillus fumigatus by QM/MM calculations

(2017) Xiya Wang et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Fast and easy liquid chromatography–mass spectrometry method for evaluation of postharvest fruit safety by determination of mycotoxins: Fumitremorgin C and verruculogen

(2017) Emilia Fornal et al.   POSTHARVEST BIOLOGY AND TECHNOLOGY

Beyond ferryl-mediated hydroxylation: 40 years of the rebound mechanism and C–H activation

(2016) Xiongyi Huang et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Biophysical Characterization of Fluorotyrosine Probes Site-Specifically Incorporated into Enzymes: E. coli Ribonucleotide Reductase As an Example

(2016) Paul H. Oyala et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Defining the Role of Tyrosine and Rational Tuning of Oxidase Activity by Genetic Incorporation of Unnatural Tyrosine Analogs

(2015) Yang Yu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Endoperoxide formation by an α-ketoglutarate-dependent mononuclear non-haem iron enzyme

(2015) Wupeng Yan et al.   NATURE

Hole hopping through tyrosine/tryptophan chains protects proteins from oxidative damage

(2015) Harry B. Gray et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of the C5 Stereoinversion Reaction in the Biosynthesis of Carbapenem Antibiotics

(2014) W.-c. Chang et al.   SCIENCE

Conformational Effects on the pro - S Hydrogen Abstraction Reaction in Cyclooxygenase-1: An Integrated QM/MM and MD Study

(2013) Christo Z. Christov et al.   BIOPHYSICAL JOURNAL

Elucidation of the Fe(iv)=O intermediate in the catalytic cycle of the halogenase SyrB2

(2013) Shaun D. Wong et al.   NATURE

Aryl Azide Photochemistry in Defined Protein Environments

(2013) Josephine L. Morris et al.   ORGANIC LETTERS

Gene Disruption and Biochemical Characterization of Verruculogen Synthase of Aspergillus fumigatus

(2011) Naoki Kato et al.   CHEMBIOCHEM

Free Radical Lipid Peroxidation: Mechanisms and Analysis

(2011) Huiyong Yin et al.   CHEMICAL REVIEWS

Incorporation of Fluorotyrosines into Ribonucleotide Reductase Using an Evolved, Polyspecific Aminoacyl-tRNA Synthetase

(2011) Ellen C. Minnihan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Equilibration of Tyrosyl Radicals (Y356•, Y731•, Y730•) in the Radical Propagation Pathway of the Escherichia coli Class Ia Ribonucleotide Reductase

(2011) Kenichi Yokoyama et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Prostaglandin H synthase: Resolved and unresolved mechanistic issues

(2009) Ah-Lim Tsai et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Probing the Coupling between Proton and Electron Transfer in Photosystem II Core Complexes Containing a 3-Fluorotyrosine

(2009) Fabrice Rappaport et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hydrogen Exchange Rate of Tyrosine Hydroxyl Groups in Proteins As Studied by the Deuterium Isotope Effect on CζChemical Shifts

(2009) Mitsuhiro Takeda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

FtmOx1, a non-heme Fe(ii) and α-ketoglutarate-dependent dioxygenase, catalyses the endoperoxide formation of verruculogen in Aspergillus fumigatus

(2009) Nicola Steffan et al.   ORGANIC & BIOMOLECULAR CHEMISTRY