Organocatalytic atroposelective construction of axially chiral N, N- and N, S-1,2-azoles through novel ring formation approach

Ligand-directed two-step labeling to quantify neuronal glutamate receptor trafficking

(2021) Kento Ojima et al.   Nature Communications

Recent Advances in Catalytic Asymmetric Construction of Atropisomers

(2021) Jun Kee Cheng et al.   CHEMICAL REVIEWS

Efficient Synthesis of Sulfur-Stereogenic Sulfoximines via Ru(II)-Catalyzed Enantioselective C–H Functionalization Enabled by Chiral Carboxylic Acid

(2021) Tao Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metal-free oxidative cross-coupling enabled practical synthesis of atropisomeric QUINOL and its derivatives

(2021) Peng-Ying Jiang et al.   Nature Communications

Organocatalytic Enantioselective Construction of Chiral Azepine Skeleton Bearing Multiple‐Stereogenic Elements

(2021) Shengli Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rational design of a new antibiotic class for drug-resistant infections

(2021) Thomas F. Durand-Reville et al.   NATURE

Diversity-Oriented Enantioselective Construction of Atropisomeric Heterobiaryls and N -Aryl Indoles via Vinylidene Ortho -Quinone Methides

(2021) Da Xu et al.   CCS Chemistry

Intermolecular Palladium(0)-Catalyzed Atropo-enantioselective C–H Arylation of Heteroarenes

(2020) Qui-Hien Nguyen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cu(II)/TEMPO‐Catalyzed Enantioselective C(sp3)–H Alkynylationof Tertiary Cyclic Amines via Shono‐type Oxidation

(2020) Pei-Sen Gao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium(III)‐Catalyzed Atroposelective Synthesis of Biaryls by C−H Activation and Intermolecular Coupling with Sterically Hindered Alkynes

(2020) Fen Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modern Stereoselective Synthesis of Chiral Sulfinyl Compounds

(2020) Elżbieta Wojaczyńska et al.   CHEMICAL REVIEWS

Molecular Hybrids Integrated with Benzimidazole and Pyrazole Structural Motifs: Design, Synthesis, Biological Evaluation, and Molecular Docking Studies

(2020) Ramar Sivaramakarthikeyan et al.   ACS Omega

Design and Atroposelective Construction of IAN analogues by Organocatalytic Asymmetric Heteroannulation of Alkynes

(2020) Lei Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Harnessing Sulfinyl Nitrenes: A Unified One-Pot Synthesis of Sulfoximines and Sulfonimidamides

(2020) Thomas Q. Davies et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-Catalyzed Atroposelective Oxidative C–H/C–H Cross-Coupling Reaction of 1-Aryl Isoquinoline Derivatives with Electron-Rich Heteroarenes

(2020) Qiang Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Regioselective functionalization of aryl azoles as powerful tool for the synthesis of pharmaceutically relevant targets

(2020) Ferdinand H. Lutter et al.   Nature Communications

Syntheses and Transformations of Sulfoximines

(2020) Wenting Zheng et al.   CHEMICAL RECORD

Vinylidene ortho-Quinone Methides: Unique Chiral Reaction Intermediates in Catalytic Asymmetric Synthesis

(2019) Sachie Arae et al.   CHIMIA

Disparate Catalytic Scaffolds for Atroposelective Cyclodehydration

(2019) Yongseok Kwon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient Kinetic Resolution of Sulfur-Stereogenic Sulfoximines by Exploiting CpX RhIII -Catalyzed C−H Functionalization

(2019) Marcus Brauns et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Discovery of novel pyrazole derivatives as potential anticancer agents in MCL

(2019) Fansheng Ran et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Bond-Forming and -Breaking Reactions at Sulfur(IV): Sulfoxides, Sulfonium Salts, Sulfur Ylides, and Sulfinate Salts

(2019) Daniel Kaiser et al.   CHEMICAL REVIEWS

Pharmacokinetic Study of NADPH Oxidase Inhibitor Ewha-18278, a Pyrazole Derivative

(2019) Seul Gee Lee et al.   Pharmaceutics

Asymmetric Synthesis of Chiral Sulfoximines through the S-Alkylation of Sulfinamides

(2019) Yusuke Aota et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Asymmetric Annulation of ortho -Alkynylanilines: Synthesis of Axially Chiral Naphthyl-C2-indoles

(2019) Lei Peng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Efficient Synthesis of Cyclic Sulfoximines from N‐Propargylsulfinamides through Sulfur–Carbon Bond Formation

(2019) Yusuke Aota et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric Synthesis of Chiral Sulfoximines via the S-Arylation of Sulfinamides

(2019) Yusuke Aota et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Asymmetric Synthesis of Indole-Based Chiral Heterocycles: Strategies, Reactions, and Outreach

(2019) Yu-Chen Zhang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Construction of Axially Chiral Compounds via Asymmetric Organocatalysis

(2018) Yong-Bin Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Divergent Control of Point and Axial Stereogenicity: Catalytic Enantioselective C−N Bond-Forming Cross-Coupling and Catalyst-Controlled Atroposelective Cyclodehydration

(2018) Yongseok Kwon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Atroposelective Intramolecular [4+2] Cycloaddition: Synthesis of Axially Chiral Heterobiaryls

(2018) Yidong Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral sulfoxides: advances in asymmetric synthesis and problems with the accurate determination of the stereochemical outcome

(2018) Jianlin Han et al.   CHEMICAL SOCIETY REVIEWS

Organocatalytic Enantioselective Construction of Axially Chiral Sulfone-Containing Styrenes

(2018) Shiqi Jia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Encorafenib plus binimetinib versus vemurafenib or encorafenib in patients with BRAF -mutant melanoma (COLUMBUS): a multicentre, open-label, randomised phase 3 trial

(2018) Reinhard Dummer et al.   LANCET ONCOLOGY

Stress-dependent miR-980 regulation of Rbfox1/A2bp1 promotes ribonucleoprotein granule formation and cell survival

(2018) Mariya M. Kucherenko et al.   Nature Communications

Three-Dimensional Heterocycles by Iron-Catalyzed Ring-Closing Sulfoxide Imidation

(2018) Hao Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of Axially Chiral Benzocarbazole Derivatives Based on Catalytic Enantioselective Hydroarylation of Alkynes

(2018) Sachie Arae et al.   ORGANIC LETTERS

Asymmetric Mannich Reaction and Construction of Axially Chiral Sulfone-Containing Styrenes in One Pot from α-Amido Sulfones Based on the Waste–Reuse Strategy

(2018) Dongmei Li et al.   ORGANIC LETTERS

Enantioselective Construction of Vicinal Diaxial Styrenes and Multiaxis System via Organocatalysis

(2018) Yu Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric One-Pot Construction of Three Stereogenic Elements: Chiral Carbon Center, Stereoisomeric Alkenes, and Chirality of Axial Styrenes

(2018) Anqi Huang et al.   ORGANIC LETTERS

Organocatalytic Asymmetric Atroposelective Construction of Axially Chiral 1,4-Distyrene 2,3-Naphthalene Diols

(2018) Shan Li et al.   ORGANIC LETTERS

Organocatalytic asymmetric arylation of indoles enabled by azo groups

(2017) Liang-Wen Qi et al.   Nature Chemistry

Enantioselective Synthesis of Indole-Based Biaryl Atropisomers via Palladium-Catalyzed Dynamic Kinetic Intramolecular C–H Cyclization

(2017) Congfa He et al.   ACS Catalysis

Benzo[c]isothiazole 2-Oxides: Three-Dimensional Heterocycles with Cross-Coupling and Functionalization Potential

(2016) Philip Lamers et al.   ADVANCED SYNTHESIS & CATALYSIS

Design and Enantioselective Construction of Axially Chiral Naphthyl-Indole Skeletons

(2016) Hong-Hao Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Functionalized isoxazole and isothiazole ligands: design, synthesis, palladium complexes, homogeneous and heterogeneous catalysis in aqueous media

(2016) N. A. Bumagin et al.   RUSSIAN CHEMICAL BULLETIN

Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors

(2016) Andrea M. Zuhl et al.   Nature Communications

Sulfoximines: A Neglected Opportunity in Medicinal Chemistry

(2013) Ulrich Lücking   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Crizotinib

(2011) Alice T. Shaw et al.   NATURE REVIEWS DRUG DISCOVERY

Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products

(2010) Gerhard Bringmann et al.   CHEMICAL REVIEWS