Design and Atroposelective Construction of IAN analogues by Organocatalytic Asymmetric Heteroannulation of Alkynes

Chiral-Phosphoric-Acid-Catalyzed Atroposelective C-H Amination of Arenes

(2020) Bin Tan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ir-Catalyzed Atroposelective Desymmetrization of Heterobiaryls: Hydroarylation of Vinyl Ethers and Bicycloalkenes

(2020) Antonio Romero-Arenas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Enantioselective Construction of Heterocycle-Substituted Styrenes with Chiral Atropisomerism

(2020) Quan-Zhe Li et al.   ORGANIC LETTERS

Axially Chiral Aryl‐Alkene‐Indole Framework: A Nascent Member of the Atropisomeric Family and Its Catalytic Asymmetric Construction

(2020) Cong‐Shuai Wang et al.   CHINESE JOURNAL OF CHEMISTRY

Enantioselective Synthesis of Biaryl Atropisomers via Pd-Catalyzed C-H Olefination using Chiral Spiro Phosphoric Acid Ligands

(2019) Jun Luo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phosphine-Catalyzed Intermolecular Annulations of Fluorinated ortho -Aminophenones with Alkynones - The Switchable [4+2] or [4+2]/[3+2] Cycloaddition

(2019) Yanshun Zhang et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Kinetic Resolution by Enantioselective Aromatization: Conversion of Racemic Intermediates of the Barton-Zard Reaction into Enantioenriched 3-Arylpyrroles

(2019) Sheng-Cai Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Barton–Zard Reaction To Access 3-Pyrrole-Containing Axially Chiral Skeletons

(2019) Xiao-Long He et al.   ACS Catalysis

Asymmetric Construction of Axially Chiral 2-Arylpyrroles via Chirality Transfer of Atropisomeric Alkenes

(2019) Bin Tan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-Catalyzed Atroposelective C–H Arylation: Efficient Synthesis of Axially Chiral Heterobiaryls

(2019) Qiang Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rh(III)-Catalyzed Asymmetric Synthesis of Axially Chiral Biindolyls by Merging C–H Activation and Nucleophilic Cyclization

(2019) Miaomiao Tian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Atroposelective Friedländer Quinoline Heteroannulation

(2019) You-Dong Shao et al.   ORGANIC LETTERS

Rational design, enantioselective synthesis and catalytic applications of axially chiral EBINOLs

(2019) Yong-Bin Wang et al.   Nature Catalysis

A Bulky Chiral N-Heterocyclic Carbene Palladium Catalyst Enables Highly Enantioselective Suzuki–Miyaura Cross-Coupling Reactions for the Synthesis of Biaryl Atropisomers

(2019) Di Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Asymmetric Annulation of ortho -Alkynylanilines: Synthesis of Axially Chiral Naphthyl-C2-indoles

(2019) Lei Peng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Control of Both Helical and Axial Stereogenic Elements though an Organocatalytic Approach

(2019) Shiqi Jia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic atroposelective construction of axially chiral arylquinones

(2019) Shuai Zhu et al.   Nature Communications

Construction of Axially Chiral Compounds via Asymmetric Organocatalysis

(2018) Yong-Bin Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Organocatalytic Atroposelective Intramolecular [4+2] Cycloaddition: Synthesis of Axially Chiral Heterobiaryls

(2018) Yidong Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dynamic Kinetic Resolution of Heterobiaryl Ketones by Zinc-Catalyzed Asymmetric Hydrosilylation

(2018) Valentín Hornillos et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cobalt complex catalyzed atom-economical synthesis of quinoxaline, quinoline and 2-alkylaminoquinoline derivatives

(2018) Sujan Shee et al.   CHEMICAL COMMUNICATIONS

Organocatalytic Enantioselective Construction of Axially Chiral Sulfone-Containing Styrenes

(2018) Shiqi Jia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Carbonyl catalysis enables a biomimetic asymmetric Mannich reaction

(2018) Jianfeng Chen et al.   SCIENCE

Phosphine-Free NNN-Manganese Complex Catalyzed α-Alkylation of Ketones with Primary Alcohols and Friedländer Quinoline Synthesis

(2018) Milan K. Barman et al.   ADVANCED SYNTHESIS & CATALYSIS

Dynamic Kinetic Asymmetric Heck Reaction for the Simultaneous Generation of Central and Axial Chirality

(2018) José A. Carmona et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Asymmetric One-Step Desymmetrizing Dearomatization Reaction of Indoles: Development and Bioactivity Evaluation

(2018) Lei Peng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Cyclizative Dimerization of ( ortho ‐Alkynyl Phenyl) (Methoxymethyl) Sulfides with Palladium(II) Bisoxazoline Catalyst

(2018) Cheng Peng et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Construction of Vicinal Diaxial Styrenes and Multiaxis System via Organocatalysis

(2018) Yu Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NHC-Cu(I)-Catalyzed Friedländer-Type Annulation of Fluorinated o-Aminophenones with Alkynes on Water: Competitive Base-Catalyzed Dibenzo[b,f][1,5]diazocine Formation

(2017) Paweł Czerwiński et al.   JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic asymmetric arylation of indoles enabled by azo groups

(2017) Liang-Wen Qi et al.   Nature Chemistry

Axially Chiral P,N-Ligands: Some Recent Twists and Turns

(2017) Balaji V. Rokade et al.   ACS Catalysis

Design and Enantioselective Construction of Axially Chiral Naphthyl-Indole Skeletons

(2016) Hong-Hao Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of axially chiral heterobiaryl alkynes via dynamic kinetic asymmetric alkynylation

(2016) Valentín Hornillos et al.   CHEMICAL COMMUNICATIONS

Synthesis of IAN-type N,N-Ligands via Dynamic Kinetic Asymmetric Buchwald–Hartwig Amination

(2016) Pedro Ramírez-López et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enzyme-Inspired Axially Chiral Pyridoxamines Armed with a Cooperative Lateral Amine Chain for Enantioselective Biomimetic Transamination

(2016) Yong Ethan Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Kinetic Resolution of Axially Chiral 5- or 8-Substituted Quinolines via Asymmetric Transfer Hydrogenation

(2016) Jie Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and Application of Chiral Spiro Cp Ligands in Rhodium-Catalyzed Asymmetric Oxidative Coupling of Biaryl Compounds with Alkenes

(2016) Jun Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Dynamic Kinetic C–P Cross–Coupling for the Asymmetric Synthesis of Axially Chiral P,N Ligands

(2016) Pedro Ramírez-López et al.   ACS Catalysis

Nonbiaryl and Heterobiaryl Atropisomers: Molecular Templates with Promise for Atropselective Chemical Transformations

(2015) Elango Kumarasamy et al.   CHEMICAL REVIEWS

Catalytic Enantioselective Synthesis of Atropisomeric Biaryls: A Cation-Directed Nucleophilic Aromatic Substitution Reaction

(2014) Roly J. Armstrong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Construction of Axial Chirality by Rhodium-Catalyzed Asymmetric Dehydrogenative Heck Coupling of Biaryl Compounds with Alkenes

(2014) Jun Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Complete Field Guide to Asymmetric BINOL-Phosphate Derived Brønsted Acid and Metal Catalysis: History and Classification by Mode of Activation; Brønsted Acidity, Hydrogen Bonding, Ion Pairing, and Metal Phosphates

(2014) Dixit Parmar et al.   CHEMICAL REVIEWS

Synthesis and in vitro cytotoxic effect of 6-amino-substituted 11H- and 11Me-indolo[3,2-c]quinolines

(2014) Ning Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Pd(II)-Catalyzed Intermolecular Direct C–H Bond Iodination: An Efficient Approach toward the Synthesis of Axially Chiral Compounds via Kinetic Resolution

(2014) De-Wei Gao et al.   ACS Catalysis

Antibacterial activity of quinoxalines, quinazolines, and 1,5-naphthyridines

(2013) Ajit K. Parhi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

P,N ligands in asymmetric catalysis

(2013) Michael P. Carroll et al.   CHEMICAL SOCIETY REVIEWS

Synthesis of Axially Chiral 1,1′-Binaphthalenes by Palladium-Catalysed Cross-Coupling Reactions of Triorganoindium Reagents

(2013) Ángeles Mosquera et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Dynamic Kinetic Cross-Coupling Strategy for the Asymmetric Synthesis of Axially Chiral Heterobiaryls

(2013) Abel Ros et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Synthesis of QUINAP via Dynamic Kinetic Resolution

(2013) Vikram Bhat et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Design, Preparation, and Implementation of an Imidazole-Based Chiral Biaryl P,N-Ligand for Asymmetric Catalysis

(2013) Flavio S. P. Cardoso et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hindered biaryls by C–H coupling: bisoxazoline-Pd catalysis leading to enantioselective C–H coupling

(2012) Kazuya Yamaguchi et al.   Chemical Science

Enantioselective Synthesis of Axially Chiral 1-Arylisoquinolines by Rhodium-Catalyzed [2+2+2] Cycloaddition

(2011) Norifumi Sakiyama et al.   CHEMISTRY-A EUROPEAN JOURNAL

Revealing Atropisomer Axial Chirality in Drug Discovery

(2011) Steven R. LaPlante et al.   ChemMedChem

Assessing Atropisomer Axial Chirality in Drug Discovery and Development

(2011) Steven R. LaPlante et al.   JOURNAL OF MEDICINAL CHEMISTRY

Nickel-Catalyzed Regio- and Enantioselective Annulation Reactions of 1,2,3,4-Benzothiatriazine-1,1(2H)-dioxides with Allenes

(2010) Tomoya Miura et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products

(2010) Gerhard Bringmann et al.   CHEMICAL REVIEWS

Asymmetric Synthesis of Axially Chiral 1-Aryl-5,6,7,8-tetrahydroquinolines by Cobalt-Catalyzed [2 + 2 + 2] Cycloaddition Reaction of 1-Aryl-1,7-octadiynes and Nitriles

(2010) Marko Hapke et al.   JOURNAL OF ORGANIC CHEMISTRY

The Challenge of Atropisomerism in Drug Discovery

(2009) Jonathan Clayden et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Dehydrative Cyclization of ω-Hydroxy Allyl Alcohols Catalyzed by Ruthenium Complexes

(2009) Shinji Tanaka et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Advances in the Friedländer Reaction

(2009) José Marco-Contelles et al.   CHEMICAL REVIEWS

Total synthesis of chiral biaryl natural products by asymmetric biaryl coupling

(2009) Marisa C. Kozlowski et al.   CHEMICAL SOCIETY REVIEWS