A modified multiparametric assay using HepaRG cells for predicting the degree of drug-induced liver injury risk
出版年份 2016 全文链接
标题
A modified multiparametric assay using HepaRG cells for predicting the degree of drug-induced liver injury risk
作者
关键词
-
出版物
JOURNAL OF APPLIED TOXICOLOGY
Volume 37, Issue 3, Pages 382-390
出版商
Wiley
发表日期
2016-08-03
DOI
10.1002/jat.3371
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Setting Clinical Exposure Levels of Concern for Drug-Induced Liver Injury (DILI) Using Mechanisticin vitroAssays
- (2015) Falgun Shah et al. TOXICOLOGICAL SCIENCES
- Multiparametric assay using HepaRG cells for predicting drug-induced liver injury
- (2015) Takafumi Tomida et al. TOXICOLOGY LETTERS
- A Correlation Between the In Vitro Drug Toxicity of Drugs to Cell Lines That Express Human P450s and Their Propensity to Cause Liver Injury in Humans
- (2013) Frida Gustafsson et al. TOXICOLOGICAL SCIENCES
- Predictivity of dog co-culture model, primary human hepatocytes and HepG2 cells for the detection of hepatotoxic drugs in humans
- (2013) Franck A. Atienzar et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Evaluation of the use of imaging parameters for the detection of compound-induced hepatotoxicity in 384-well cultures of HepG2 cells and cryopreserved primary human hepatocytes
- (2013) Helen Garside et al. TOXICOLOGY IN VITRO
- A high content screening assay to predict human drug-induced liver injury during drug discovery
- (2013) Mikael Persson et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
- Prediction of Liver Injury Induced by Chemicals in Human With a Multiparametric Assay on Isolated Mouse Liver Mitochondria
- (2012) Mathieu Porceddu et al. TOXICOLOGICAL SCIENCES
- Use of Micropatterned Cocultures to Detect Compounds That Cause Drug-Induced Liver Injury in Humans
- (2012) Salman R. Khetani et al. TOXICOLOGICAL SCIENCES
- Development of a Multiparametric Cell-based Protocol to Screen and Classify the Hepatotoxicity Potential of Drugs
- (2012) Laia Tolosa et al. TOXICOLOGICAL SCIENCES
- FDA-approved drug labeling for the study of drug-induced liver injury
- (2011) Minjun Chen et al. DRUG DISCOVERY TODAY
- Induction of vesicular steatosis by amiodarone and tetracycline is associated with up-regulation of lipogenic genes in heparg cells
- (2011) Sébastien Anthérieu et al. HEPATOLOGY
- Severe acute liver injury associated with lumiracoxib
- (2011) Peter I Pillans et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Mechanism-based selection of compounds for the development of innovative in vitro approaches to hepatotoxicity studies in the LIINTOP project
- (2010) María José Gómez-Lechón et al. TOXICOLOGY IN VITRO
- Cellular Imaging Predictions of Clinical Drug-Induced Liver Injury
- (2008) Jinghai J. Xu et al. TOXICOLOGICAL SCIENCES
- Dose- and time-dependent effects of phenobarbital on gene expression profiling in human hepatoma HepaRG cells
- (2008) Carine B. Lambert et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now