Glycolysis inhibition ameliorates brain injury after ischemic stroke by promoting the function of myeloid-derived suppressor cells

Glycolysis fuels phosphoinositide 3-kinase signaling to bolster T cell immunity

(2021) Ke Xu et al.   SCIENCE

Early glycolytic reprogramming controls microglial inflammatory activation

(2021) Junjie Cheng et al.   Journal of Neuroinflammation

Regulatory T cell is critical for interleukin-33-mediated neuroprotection against stroke

(2020) Xinjing Liu et al.   EXPERIMENTAL NEUROLOGY

Glycolysis – a key player in the inflammatory response

(2020) Gonzalo Soto‐Heredero et al.   FEBS Journal

Immune responses to stroke: mechanisms, modulation, and therapeutic potential

(2020) Costantino Iadecola et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulatory myeloid cells paralyze T cells through cell–cell transfer of the metabolite methylglyoxal

(2020) Tobias Baumann et al.   NATURE IMMUNOLOGY

Interleukin‐17 and ischaemic stroke

(2020) Qiaohui Zhang et al.   IMMUNOLOGY

PFKFB3 in Smooth Muscle Promotes Vascular Remodeling in Pulmonary Arterial Hypertension

(2019) Laszlo Kovacs et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cardioprotective Role of Myeloid-Derived Suppressor Cells in Heart Failure

(2018) Ling Zhou et al.   CIRCULATION

Regulatory T-cells within bone marrow-derived stem cells actively confer immunomodulatory and neuroprotective effects against stroke

(2018) Elliot G Neal et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Diagnosis and Management of Acute Ischemic Stroke

(2018) Tasneem F. Hasan et al.   MAYO CLINIC PROCEEDINGS

Myeloid-derived suppressor cells coming of age

(2018) Filippo Veglia et al.   NATURE IMMUNOLOGY

Role of Immune Cells Migrating to the Ischemic Brain

(2018) Anna M. Planas   STROKE

Glutathione Primes T Cell Metabolism for Inflammation

(2017) Tak W. Mak et al.   IMMUNITY

Glycolysis regulates the expansion of myeloid-derived suppressor cells in tumor-bearing hosts through prevention of ROS-mediated apoptosis

(2017) Shiou-Ling Jian et al.   Cell Death & Disease

Regulation of endothelial intracellular adenosine via adenosine kinase epigenetically modulates vascular inflammation

(2017) Yiming Xu et al.   Nature Communications

CD11b+Gr-1+myeloid-derived suppressor cells reduce atherosclerotic lesion development in LDLr deficient mice

(2016) Amanda C. Foks et al.   CARDIOVASCULAR RESEARCH

HIF1α and metabolic reprogramming in inflammation

(2016) Sarah E. Corcoran et al.   JOURNAL OF CLINICAL INVESTIGATION

Fatty acid synthesis configures the plasma membrane for inflammation in diabetes

(2016) Xiaochao Wei et al.   NATURE

Rapamycin Prolongs Cardiac Allograft Survival in a Mouse Model by Inducing Myeloid-Derived Suppressor Cells

(2015) T. Nakamura et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Acute Stroke Intervention

(2015) Shyam Prabhakaran et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Lactate Regulates Metabolic and Pro-inflammatory Circuits in Control of T Cell Migration and Effector Functions

(2015) Robert Haas et al.   PLOS BIOLOGY

Endothelial PFKFB3 Plays a Critical Role in Angiogenesis

(2014) Yiming Xu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Understanding the Multifaceted Role of Inflammatory Mediators in Ischemic Stroke

(2014) D. Amantea et al.   CURRENT MEDICINAL CHEMISTRY

Subsets of Myeloid-Derived Suppressor Cells in Tumor-Bearing Mice

(2014) J.-I. Youn et al.   JOURNAL OF IMMUNOLOGY

The Role of Myeloid-Derived Suppressor Cells in Immune Ontogeny

(2014) Soren Gantt et al.   Frontiers in Immunology

An Updated Definition of Stroke for the 21st Century

(2013) Ralph L. Sacco et al.   STROKE

Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke

(2012) M. Gelderblom et al.   BLOOD

On the armament and appearances of human myeloid-derived suppressor cells

(2012) Isabel Poschke et al.   CLINICAL IMMUNOLOGY

Gr-1+CD11b+Myeloid-derived Suppressor Cells Suppress Inflammation and Promote Insulin Sensitivity in Obesity

(2011) Sheng Xia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

5-Fluorouracil Selectively Kills Tumor-Associated Myeloid-Derived Suppressor Cells Resulting in Enhanced T Cell-Dependent Antitumor Immunity

(2010) J. Vincent et al.   CANCER RESEARCH

Myeloid-Derived Suppressor Cells Prevent Type 1 Diabetes in Murine Models

(2010) B. Yin et al.   JOURNAL OF IMMUNOLOGY