标题
Polygenic scores in biomedical research
作者
关键词
-
出版物
NATURE REVIEWS GENETICS
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2022-03-30
DOI
10.1038/s41576-022-00470-z
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- A tool for translating polygenic scores onto the absolute scale using summary statistics
- (2022) Oliver Pain et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- A roadmap to increase diversity in genomic studies
- (2022) Segun Fatumo et al. NATURE MEDICINE
- Use of multiple polygenic risk scores for distinguishing schizophrenia-spectrum disorder and affective psychosis categories in a first-episode sample; the EU-GEI study
- (2022) Victoria Rodriguez et al. PSYCHOLOGICAL MEDICINE
- How Communicating Polygenic and Clinical Risk for Atherosclerotic Cardiovascular Disease Impacts Health Behavior: an Observational Follow-up Study
- (2022) Elisabeth Widén et al. Circulation-Genomic and Precision Medicine
- The broken promise that undermines human genome research
- (2021) Kendall Powell NATURE
- Improving reporting standards for polygenic scores in risk prediction studies
- (2021) Hannah Wand et al. NATURE
- The Polygenic Score Catalog as an open database for reproducibility and systematic evaluation
- (2021) Samuel A. Lambert et al. NATURE GENETICS
- Evaluation of polygenic prediction methodology within a reference-standardized framework
- (2021) Oliver Pain et al. PLoS Genetics
- A call for training programmes in cardiovascular genomics
- (2021) Maya S. Safarova et al. Nature Reviews Cardiology
- Problems with Using Polygenic Scores to Select Embryos
- (2021) Patrick Turley et al. NEW ENGLAND JOURNAL OF MEDICINE
- The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice
- (2021) Francesca Forzano et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- The power of genetic diversity in genome-wide association studies of lipids
- (2021) Sarah E. Graham et al. NATURE
- Large uncertainty in individual polygenic risk score estimation impacts PRS-based risk stratification
- (2021) Yi Ding et al. NATURE GENETICS
- Responsible use of polygenic risk scores in the clinic: potential benefits, risks and gaps
- (2021) et al. NATURE MEDICINE
- Predictive Utility of Polygenic Risk Scores for Coronary Heart Disease in Three Major Racial and Ethnic Groups
- (2020) Ozan Dikilitas et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses
- (2020) Haoyu Zhang et al. NATURE GENETICS
- Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers
- (2020) Nina Mars et al. NATURE MEDICINE
- Combined Utility of 25 Disease and Risk Factor Polygenic Risk Scores for Stratifying Risk of All-Cause Mortality
- (2020) Allison Meisner et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Impute.me: An Open-Source, Non-profit Tool for Using Data From Direct-to-Consumer Genetic Testing to Calculate and Interpret Polygenic Risk Scores
- (2020) Lasse Folkersen et al. Frontiers in Genetics
- Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions
- (2020) Akl C. Fahed et al. Nature Communications
- The role of polygenic risk and susceptibility genes in breast cancer over the course of life
- (2020) Nina Mars et al. Nature Communications
- BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors
- (2019) Andrew Lee et al. GENETICS IN MEDICINE
- Clinical use of current polygenic risk scores may exacerbate health disparities
- (2019) Alicia R. Martin et al. NATURE GENETICS
- Complex Trait Prediction from Genome Data: Contrasting EBV in Livestock to PRS in Humans
- (2019) Naomi R. Wray et al. GENETICS
- Polygenic adaptation on height is overestimated due to uncorrected stratification in genome-wide association studies
- (2019) Mashaal Sohail et al. eLife
- Penetrance and Pleiotropy of Polygenic Risk Scores for Schizophrenia in 106,160 Patients Across Four Health Care Systems
- (2019) Amanda B. Zheutlin et al. AMERICAN JOURNAL OF PSYCHIATRY
- Towards clinical utility of polygenic risk scores
- (2019) Samuel A Lambert et al. HUMAN MOLECULAR GENETICS
- Screening Human Embryos for Polygenic Traits Has Limited Utility
- (2019) Ehud Karavani et al. CELL
- Tread Lightly Interpreting Polygenic Tests of Selection
- (2018) John Novembre et al. GENETICS
- The personal and clinical utility of polygenic risk scores
- (2018) Ali Torkamani et al. NATURE REVIEWS GENETICS
- Tread Lightly Interpreting Polygenic Tests of Selection
- (2018) John Novembre et al. GENETICS
- Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables
- (2018) Emma Ahlqvist et al. Lancet Diabetes & Endocrinology
- Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations
- (2018) Amit V. Khera et al. NATURE GENETICS
- Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes
- (2018) Nasim Mavaddat et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults
- (2018) Michael Inouye et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers
- (2017) Karoline B Kuchenbaecker et al. JNCI-Journal of the National Cancer Institute
- Multi-polygenic score approach to trait prediction
- (2017) E Krapohl et al. MOLECULAR PSYCHIATRY
- Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers
- (2017) Karoline B Kuchenbaecker et al. JNCI-Journal of the National Cancer Institute
- Incorporating a Genetic Risk Score Into Coronary Heart Disease Risk EstimatesCLINICAL PERSPECTIVE
- (2016) Iftikhar J. Kullo et al. CIRCULATION
- Developing and evaluating polygenic risk prediction models for stratified disease prevention
- (2016) Nilanjan Chatterjee et al. NATURE REVIEWS GENETICS
- Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease
- (2016) Amit V. Khera et al. NEW ENGLAND JOURNAL OF MEDICINE
- Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials
- (2015) Jessica L Mega et al. LANCET
- Leveraging the electronic health record to implement genomic medicine
- (2012) Iftikhar J. Kullo et al. GENETICS IN MEDICINE
- Evolutionary Genetics of Coronary Heart Disease
- (2009) Keyue Ding et al. CIRCULATION
- Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
- (2009) Shaun M. Purcell et al. NATURE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started