Single-cell Wnt signaling niches maintain stemness of alveolar type 2 cells

Automated cell-type classification in intact tissues by single-cell molecular profiling

(2018) Monica Nagendran et al.   eLife

A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma

(2017) Tuomas Tammela et al.   NATURE

Visualization of a short-range Wnt gradient in the intestinal stem-cell niche

(2016) Henner F. Farin et al.   NATURE

Fatty acylation of proteins: The long and the short of it

(2016) Marilyn D. Resh   PROGRESS IN LIPID RESEARCH

Emergence of a Wave of Wnt Signaling that Regulates Lung Alveologenesis by Controlling Epithelial Self-Renewal and Differentiation

(2016) David B. Frank et al.   Cell Reports

Keeping it together: Pulmonary alveoli are maintained by a hierarchy of cellular programs

(2015) Catriona Y. Logan et al.   BIOESSAYS

Smooth muscle cell progenitors are primed to muscularize in pulmonary hypertension

(2015) Abdul Q. Sheikh et al.   Science Translational Medicine

Nice Neighborhood: Emerging Concepts of the Stem Cell Niche

(2014) David T. Scadden   CELL

Diminished WNT ->  -catenin -> c-MYC signaling is a barrier for malignant progression of BRAFV600E-induced lung tumors

(2014) J. Juan et al.   GENES & DEVELOPMENT

Alveolar progenitor and stem cells in lung development, renewal and cancer

(2014) Tushar J. Desai et al.   NATURE

The bone marrow niche for haematopoietic stem cells

(2014) Sean J. Morrison et al.   NATURE

Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq

(2014) Barbara Treutlein et al.   NATURE

Emerging interactions between skin stem cells and their niches

(2014) Ya-Chieh Hsu et al.   NATURE MEDICINE

An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control

(2014) H. Clevers et al.   SCIENCE

Cancer statistics, 2013

(2013) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Type 2 alveolar cells are stem cells in adult lung

(2013) Christina E. Barkauskas et al.   JOURNAL OF CLINICAL INVESTIGATION

Quantitative assessment of single-cell RNA-sequencing methods

(2013) Angela R Wu et al.   NATURE METHODS

Smart-seq2 for sensitive full-length transcriptome profiling in single cells

(2013) Simone Picelli et al.   NATURE METHODS

Stem cell dynamics in the hair follicle niche

(2013) Panteleimon Rompolas et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Developmental Stage and Time Dictate the Fate of Wnt/β-Catenin-Responsive Stem Cells in the Mammary Gland

(2012) Renée van Amerongen et al.   Cell Stem Cell

Alveolar Type II Cells Possess the Capability of Initiating Lung Tumor Development

(2012) Chuwen Lin et al.   PLoS One

Evidence for type II cells as cells of origin of K-Ras-induced distal lung adenocarcinoma

(2012) X. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distal Airway Stem Cells Yield Alveoli In Vitro and during Lung Regeneration following H1N1 Influenza Infection

(2011) Pooja A. Kumar et al.   CELL

Endothelial-Derived Angiocrine Signals Induce and Sustain Regenerative Lung Alveolarization

(2011) Bi-Sen Ding et al.   CELL

The stem cell niche: lessons from the Drosophila testis

(2011) M. de Cuevas et al.   DEVELOPMENT

Drosophila Stem Cell Niches: A Decade of Discovery Suggests a Unified View of Stem Cell Regulation

(2011) Vicki P. Losick et al.   DEVELOPMENTAL CELL

Wnt/β-catenin signaling accelerates mouse lung tumorigenesis by imposing an embryonic distal progenitor phenotype on lung epithelium

(2011) Eugenia C. Pacheco-Pinedo et al.   JOURNAL OF CLINICAL INVESTIGATION

Integrin α6β4 identifies an adult distal lung epithelial population with regenerative potential in mice

(2011) Harold A. Chapman et al.   JOURNAL OF CLINICAL INVESTIGATION

Alveolar Surfactant Homeostasis and the Pathogenesis of Pulmonary Disease

(2010) Jeffrey A. Whitsett et al.   Annual Review of Medicine

Generation of mice with a conditional null allele for Wntless

(2010) April C. Carpenter et al.   GENESIS

Coronary arteries form by developmental reprogramming of venous cells

(2010) Kristy Red-Horse et al.   NATURE

NG2+ CNS Glial Progenitors Remain Committed to the Oligodendrocyte Lineage in Postnatal Life and following Neurodegeneration

(2010) Shin H. Kang et al.   NEURON

Stem Cells and Niches: Mechanisms That Promote Stem Cell Maintenance throughout Life

(2008) Sean J. Morrison et al.   CELL

Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme

(2008) J. Rajagopal et al.   DEVELOPMENT

The branching programme of mouse lung development

(2008) Ross J. Metzger et al.   NATURE