Genome mining of the sordarin biosynthetic gene cluster from Sordaria araneosa Cain ATCC 36386: characterization of cycloaraneosene synthase and GDP-6-deoxyaltrose transferase

An Unusual Terpene Cyclization Mechanism Involving a Carbon-Carbon Bond Rearrangement

(2015) Ayuko Meguro et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An update to polyketide synthase and non-ribosomal synthetase genes and nomenclature in Fusarium

(2015) Frederik T. Hansen et al.   FUNGAL GENETICS AND BIOLOGY

Biosynthesis of Versipelostatin: Identification of an Enzyme-Catalyzed [4+2]-Cycloaddition Required for Macrocyclization of Spirotetronate-Containing Polyketides

(2015) Takuya Hashimoto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Computational approaches to natural product discovery

(2015) Marnix H Medema et al.   Nature Chemical Biology

Elucidation of Pseurotin Biosynthetic Pathway Points to Trans-ActingC-Methyltransferase: Generation of Chemical Diversity

(2014) Yuta Tsunematsu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Advances in understanding glycosyltransferases from a structural perspective

(2014) Tracey M Gloster   CURRENT OPINION IN STRUCTURAL BIOLOGY

The first structure of a bacterial diterpene cyclase: CotB2

(2014) Ronja Janke et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The crystal structure of human GDP-L-fucose synthase

(2013) H. Zhou et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Genetic Dissection of Sesquiterpene Biosynthesis byFusarium fujikuroi

(2013) Nelson L. Brock et al.   CHEMBIOCHEM

Biosynthesis of GDP-fucose and Other Sugar Nucleotides in the Blood Stages ofPlasmodium falciparum

(2013) Sílvia Sanz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural insights into the mechanism of translational inhibition by the fungicide sordarin

(2013) Biprashekhar Chakraborty et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Microbial genome mining for accelerated natural products discovery: is a renaissance in the making?

(2013) Brian O. Bachmann et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Strategies for mining fungal natural products

(2013) Philipp Wiemann et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Current developments and challenges in the search for a naturally selected Diels-Alderase

(2012) Hak Joong Kim et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Exploring the Structural Basis of Substrate Preferences in Baeyer-Villiger Monooxygenases

(2012) Stefano Franceschini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Substrate-Bound Crystal Structure of a Baeyer–Villiger Monooxygenase Exhibits a Criegee-like Conformation

(2012) Brahm J. Yachnin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genome Mining inStreptomyces. Elucidation of the Role of Baeyer−Villiger Monooxygenases and Non-Heme Iron-Dependent Dehydrogenase/Oxygenases in the Final Steps of the Biosynthesis of Pentalenolactone and Neopentalenolactone

(2011) Myung-Ji Seo et al.   BIOCHEMISTRY

Phylogenomic and functional domain analysis of polyketide synthases in Fusarium

(2011) Daren W. Brown et al.   Fungal Biology

Biosynthesis of lovastatin and related metabolites formed by fungal iterative PKS enzymes

(2010) Chantel D. Campbell et al.   BIOPOLYMERS

Solanapyrone Synthase, a Possible Diels-Alderase and Iterative Type I Polyketide Synthase Encoded in a Biosynthetic Gene Cluster from Alternaria solani

(2010) Ken Kasahara  et al.   CHEMBIOCHEM

Cloning of the biosynthetic gene cluster for naphthoxanthene antibiotic FD-594 from Streptomyces sp. TA-0256

(2010) Fumitaka Kudo et al.   JOURNAL OF ANTIBIOTICS

Biosynthesis of Spinosyn inSaccharopolyspora spinosa: Synthesis of Permethylated Rhamnose and Characterization of the Functions of SpnH, SpnI, and SpnK

(2010) Hak Joong Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

De novo Assembly of a 40 Mb Eukaryotic Genome from Short Sequence Reads: Sordaria macrospora, a Model Organism for Fungal Morphogenesis

(2010) Minou Nowrousian et al.   PLoS Genetics

Genome Mining inStreptomyces avermitilis: A Biochemical Baeyer−Villiger Reaction and Discovery of a New Branch of the Pentalenolactone Family Tree

(2009) Jiaoyang Jiang et al.   BIOCHEMISTRY

FR290581, a novel sordarin derivative: Synthesis and antifungal activity

(2009) Tadaatsu Hanadate et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Functional Analysis of MycE and MycF, TwoO-Methyltransferases Involved in the Biosynthesis of Mycinamicin Macrolide Antibiotics

(2009) Shengying Li et al.   CHEMBIOCHEM

Cloning and Heterologous Expression of the Cyclooctatin Biosynthetic Gene Cluster Afford a Diterpene Cyclase and Two P450 Hydroxylases

(2009) Seung-Young Kim et al.   CHEMISTRY & BIOLOGY

Physically Discrete β-Lactamase-Type Thioesterase Catalyzes Product Release in Atrochrysone Synthesis by Iterative Type I Polyketide Synthase

(2009) Takayoshi Awakawa et al.   CHEMISTRY & BIOLOGY

Synthetic Studies toward Sordarin: Building Blocks for the Terpenoid Core and for Analogues Thereof

(2009) Arnaud Schulé et al.   JOURNAL OF ORGANIC CHEMISTRY

Distribution of the antifungal agents sordarins across filamentous fungi

(2009) Francisca Vicente et al.  

Sordarin, an antifungal agent with a unique mode of action

(2008) Huan Liang   Beilstein Journal of Organic Chemistry

Identification of Diterpene Biosynthetic Gene Clusters and Functional Analysis of Labdane-Related Diterpene Cyclases inPhomopsis amygdali

(2008) Tomonobu TOYOMASU et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Mechanism and Active Site Residues of GDP-Fucose Synthase

(2008) Stephen T. B. Lau et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY