Novel Epitopes of the Influenza Virus N1 Neuraminidase Targeted by Human Monoclonal Antibodies

Mutations in the Hemagglutinin Stalk Domain Do Not Permit Escape from a Protective, Stalk-Based Vaccine-Induced Immune Response in the Mouse Model

(2021) Ericka Kirkpatrick Roubidoux et al.   mBio

The effect of calcium and magnesium on activity, immunogenicity, and efficacy of a recombinant N1/N2 neuraminidase vaccine

(2021) Luca T. Giurgea et al.   npj Vaccines

A Novel Recombinant Influenza Virus Neuraminidase Vaccine Candidate Stabilized by a Measles Virus Phosphoprotein Tetramerization Domain Provides Robust Protection from Virus Challenge in the Mouse Model

(2021) Shirin Strohmeier et al.   mBio

Antigenic drift originating from changes to the lateral surface of the neuraminidase head of influenza A virus

(2019) Atsuhiro Yasuhara et al.   Nature Microbiology

Influenza Virus Neuraminidase Structure and Functions

(2019) Julie L. McAuley et al.   Frontiers in Microbiology

Antigenic Drift of the Influenza A(H1N1)pdm09 Virus Neuraminidase Results in Reduced Effectiveness of A/California/7/2009 (H1N1pdm09)-Specific Antibodies

(2019) Jin Gao et al.   mBio

Mucosal Immunity against Neuraminidase Prevents Influenza B Virus Transmission in Guinea Pigs

(2019) Meagan McMahon et al.   mBio

Pre-existing anti-neuraminidase antibodies are associated with shortened duration of influenza A (H1N1)pdm virus shedding and illness in naturally infected adults

(2019) Hannah E Maier et al.   CLINICAL INFECTIOUS DISEASES

Broadly protective human antibodies that target the active site of influenza virus neuraminidase

(2019) Daniel Stadlbauer et al.   SCIENCE

Evolutionary, genetic, structural characterization and its functional implications for the influenza A (H1N1) infection outbreak in India from 2009 to 2017

(2019) Sara Jones et al.   Scientific Reports

Influenza H7N9 Virus Neuraminidase-Specific Human Monoclonal Antibodies Inhibit Viral Egress and Protect from Lethal Influenza Infection in Mice

(2019) Iuliia M. Gilchuk et al.   Cell Host & Microbe

Emerging from the Shadow of Hemagglutinin: Neuraminidase Is an Important Target for Influenza Vaccination

(2019) Florian Krammer et al.   Cell Host & Microbe

Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies

(2019) Xueyong Zhu et al.   Cell Host & Microbe

Influenza Infection in Humans Induces Broadly Cross-Reactive and Protective Neuraminidase-Reactive Antibodies

(2018) Yao-Qing Chen et al.   CELL

Neuraminidase as an influenza vaccine antigen: a low hanging fruit, ready for picking to improve vaccine effectiveness

(2018) Maryna C Eichelberger et al.   CURRENT OPINION IN IMMUNOLOGY

Sialidase-Inhibiting Antibody Titers Correlate with Protection from Heterologous Influenza Virus Strains of the Same Neuraminidase Subtype

(2018) Lisa Walz et al.   JOURNAL OF VIROLOGY

NAction! How Can Neuraminidase-Based Immunity Contribute to Better Influenza Virus Vaccines?

(2018) Florian Krammer et al.   mBio

Novel Cross-Reactive Monoclonal Antibodies against Ebolavirus Glycoproteins Show Protection in a Murine Challenge Model

(2017) James Duehr et al.   JOURNAL OF VIROLOGY

A universal influenza virus vaccine candidate confers protection against pandemic H1N1 infection in preclinical ferret studies

(2017) Raffael Nachbagauer et al.   npj Vaccines

Natural and directed antigenic drift of the H1 influenza virus hemagglutinin stalk domain

(2017) Christopher S. Anderson et al.   Scientific Reports

Influenza virus neuraminidase (NA): a target for antivirals and vaccines

(2016) Anitha Jagadesh et al.   ARCHIVES OF VIROLOGY

Evaluation of Antihemagglutinin and Antineuraminidase Antibodies as Correlates of Protection in an Influenza A/H1N1 Virus Healthy Human Challenge Model

(2016) Matthew J. Memoli et al.   mBio

Origins of the 2009 H1N1 influenza pandemic in swine in Mexico

(2016) Ignacio Mena et al.   eLife

Comparative Efficacy of Monoclonal Antibodies That Bind to Different Epitopes of the 2009 Pandemic H1N1 Influenza Virus Neuraminidase

(2015) Lianlian Jiang et al.   JOURNAL OF VIROLOGY

Hemagglutinin Stalk- and Neuraminidase-Specific Monoclonal Antibodies Protect against Lethal H10N8 Influenza Virus Infection in Mice

(2015) Teddy John Wohlbold et al.   JOURNAL OF VIROLOGY

Vaccination with Adjuvanted Recombinant Neuraminidase Induces Broad Heterologous, but Not Heterosubtypic, Cross-Protection against Influenza Virus Infection in Mice

(2015) Teddy John Wohlbold et al.   mBio

Structural characterization of a protective epitope spanning A(H1N1)pdm09 influenza virus neuraminidase monomers

(2015) Hongquan Wan et al.   Nature Communications

Influenza Vaccine Effectiveness in Preventing Outpatient, Inpatient, and Severe Cases of Laboratory-Confirmed Influenza

(2013) Jesús Castilla et al.   CLINICAL INFECTIOUS DISEASES

Molecular Basis for Broad Neuraminidase Immunity: Conserved Epitopes in Seasonal and Pandemic H1N1 as Well as H5N1 Influenza Viruses

(2013) H. Wan et al.   JOURNAL OF VIROLOGY

Expression of Functional Recombinant Hemagglutinin and Neuraminidase Proteins from the Novel H7N9 Influenza Virus Using the Baculovirus Expression System

(2013) Irina Margine et al.   Jove-Journal of Visualized Experiments

A Pan-H1 Anti-Hemagglutinin Monoclonal Antibody with Potent Broad-Spectrum Efficacy In Vivo

(2012) G. S. Tan et al.   JOURNAL OF VIROLOGY

Highly Conserved Protective Epitopes on Influenza B Viruses

(2012) C. Dreyfus et al.   SCIENCE

Influenza neuraminidase

(2011) Gillian M. Air   Influenza and Other Respiratory Viruses

Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers

(2011) S. W. Gerritz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T Cell-Mediated Protection against Lethal 2009 Pandemic H1N1 Influenza Virus Infection in a Mouse Model

(2010) H. Guo et al.   JOURNAL OF VIROLOGY

The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site

(2010) Qing Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Effectiveness of seasonal 2008–2009, 2009–2010 and pandemic vaccines, to prevent influenza hospitalizations during the autumn 2009 influenza pandemic wave in Castellón, Spain. A test-negative, hospital-based, case–control study

(2010) Joan Puig-Barberà et al.   VACCINE

Estimates of US influenza-associated deaths made using four different methods

(2009) William W. Thompson et al.   Influenza and Other Respiratory Viruses

Influenza Vaccine Effectiveness Among Children 6 to 59 Months of Age During 2 Influenza Seasons

(2008) Peter G. Szilagyi   ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE

The biology of influenza viruses

(2008) Nicole M. Bouvier et al.   VACCINE