Microbes and Alzheimer’s Disease

Neuronal Cytoskeletal Dynamic Modification and Neurodegeneration Induced by Infection with Herpes Simplex Virus Type 1

(2017) Ángara Zambrano et al.   JOURNAL OF ALZHEIMERS DISEASE

Alzheimer's Disease-Specific Tau Phosphorylation is Induced by Herpes Simplex Virus Type 1

(2017) Matthew A. Wozniak et al.   JOURNAL OF ALZHEIMERS DISEASE

Protective Effect of Amyloid-β Peptides Against Herpes Simplex Virus-1 Infection in a Neuronal Cell Culture Model

(2016) Karine Bourgade et al.   JOURNAL OF ALZHEIMERS DISEASE

Reactivated herpes simplex infection increases the risk of Alzheimer's disease

(2015) Hugo Lövheim et al.   Alzheimers & Dementia

Herpes simplex infection and the risk of Alzheimer's disease: A nested case-control study

(2015) Hugo Lövheim et al.   Alzheimers & Dementia

The preclinical phase of the pathological process underlying sporadic Alzheimer’s disease

(2015) Heiko Braak et al.   BRAIN

Herpes simplex virus type 1 infection in neurons leads to production and nuclear localization of APP intracellular domain (AICD): implications for Alzheimer’s disease pathogenesis

(2015) Livia Civitelli et al.   JOURNAL OF NEUROVIROLOGY

Herpes Simplex Virus type-1 infection induces synaptic dysfunction in cultured cortical neurons via GSK-3 activation and intraneuronal amyloid-β protein accumulation

(2015) Roberto Piacentini et al.   Scientific Reports

Host entry by gamma-herpesviruses — lessons from animal viruses?

(2015) Laurent Gillet et al.   Current Opinion in Virology

Historic evidence to support a causal relationship between spirochetal infections and Alzheimer’s disease

(2015) Judith Miklossy   Frontiers in Aging Neuroscience

Different Brain Regions are Infected with Fungi in Alzheimer’s Disease

(2015) Diana Pisa et al.   Scientific Reports

Apolipoprotein E in Alzheimer's Disease: An Update

(2014) Jin-Tai Yu et al.   Annual Review of Neuroscience

β-Amyloid peptides display protective activity against the human Alzheimer’s disease-associated herpes simplex virus-1

(2014) Karine Bourgade et al.   BIOGERONTOLOGY

Etiology and Pathogenesis of Late-Onset Alzheimer’s Disease

(2014) Brian J. Balin et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Brain viral burden, neuroinflammation and neurodegeneration in HAART-treated HIV positive injecting drug users

(2014) Donald B. Smith et al.   JOURNAL OF NEUROVIROLOGY

Alzheimer's Associated β-Amyloid Protein Inhibits Influenza A Virus and Modulates Viral Interactions with Phagocytes

(2014) Mitchell R. White et al.   PLoS One

Alzheimer’s disease drug-development pipeline: few candidates, frequent failures

(2014) Jeffrey L Cummings et al.   Alzheimers Research & Therapy

Herpes simplex virus type 1 and Alzheimer’s disease: increasing evidence for a major role of the virus

(2014) Ruth F. Itzhaki   Frontiers in Aging Neuroscience

Atherosclerosis and Alzheimer - diseases with a common cause? Inflammation, oxysterols, vasculature

(2014) Richard Lathe et al.   BMC Geriatrics

Antimicrobial peptide β-defensin-1 expression is upregulated in Alzheimer’s brain

(2013) Wesley M Williams et al.   Journal of Neuroinflammation

Inflammation in Alzheimer Disease--A Brief Review of the Basic Science and Clinical Literature

(2013) T. Wyss-Coray et al.   Cold Spring Harbor Perspectives in Medicine

Susceptibility genes are enriched in those of the herpes simplex virus 1/host interactome in psychiatric and neurological disorders

(2013) Chris J. Carter   Pathogens and Disease

Intracerebral propagation of Alzheimer’s disease: Strengthening evidence of a herpes simplex virus etiology

(2012) Melvyn J. Ball et al.   Alzheimers & Dementia

Interferon-Inducible Cholesterol-25-Hydroxylase Broadly Inhibits Viral Entry by Production of 25-Hydroxycholesterol

(2012) Su-Yang Liu et al.   IMMUNITY

The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response

(2012) Mathieu Blanc et al.   IMMUNITY

Infectious Agents and Neurodegeneration

(2012) Giovanna De Chiara et al.   MOLECULAR NEUROBIOLOGY

Apolipoprotein E in Alzheimer's disease and other neurological disorders

(2011) Philip B Verghese et al.   LANCET NEUROLOGY

Evidence of the association of BIN1 and PICALM with the AD risk in contrasting European populations

(2011) Jean-Charles Lambert et al.   NEUROBIOLOGY OF AGING

Herpes simplex virus type I induces the accumulation of intracellular β-amyloid in autophagic compartments and the inhibition of the non-amyloidogenic pathway in human neuroblastoma cells

(2011) Soraya Santana et al.   NEUROBIOLOGY OF AGING

Herpes Simplex Virus Dances with Amyloid Precursor Protein while Exiting the Cell

(2011) Shi-Bin Cheng et al.   PLoS One

Activation of PKR Causes Amyloid ß-Peptide Accumulation via De-Repression of BACE1 Expression

(2011) Gerard ILL-Raga et al.   PLoS One

Antivirals Reduce the Formation of Key Alzheimer's Disease Molecules in Cell Cultures Acutely Infected with Herpes Simplex Virus Type 1

(2011) Matthew A. Wozniak et al.   PLoS One

Alzheimer's disease gene signature says: beware of brain viral infections

(2011) Elisa Porcellini et al.   Immunity & Ageing

APP, APOE, complement receptor 1, clusterin and PICALM and their involvement in the herpes simplex life cycle

(2010) C.J. Carter   NEUROSCIENCE LETTERS

The Alzheimer's Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide

(2010) Stephanie J. Soscia et al.   PLoS One

APP Processing Induced by Herpes Simplex Virus Type 1 (HSV-1) Yields Several APP Fragments in Human and Rat Neuronal Cells

(2010) Giovanna De Chiara et al.   PLoS One

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

(2009) Jean-Charles Lambert et al.   NATURE GENETICS

Herpes simplex virus type 1 DNA is located within Alzheimer's disease amyloid plaques

(2008) MA Wozniak et al.   JOURNAL OF PATHOLOGY

Seropositivity to Herpes Simplex Virus Antibodies and Risk of Alzheimer's Disease: A Population-Based Cohort Study

(2008) Luc Letenneur et al.   PLoS One