Development of Praziquantel sulphonamide derivatives as antischistosomal drugs

Structural Insights into Schistosoma mansoni Carbonic Anhydrase (SmCA) Inhibition by Selenoureido-Substituted Benzenesulfonamides

(2021) Andrea Angeli et al.   JOURNAL OF MEDICINAL CHEMISTRY

Chalcogenides-incorporating carbonic anhydrase inhibitors concomitantly reverted oxaliplatin-induced neuropathy and enhanced antiproliferative action

(2021) Damiano Tanini et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Mechanism of praziquantel action at a parasitic flatworm ion channel

(2021) Sang-Kyu Park et al.   Science Translational Medicine

Sulfonamide Inhibition Studies of an α-Carbonic Anhydrase from Schistosoma mansoni, a Platyhelminth Parasite Responsible for Schistosomiasis

(2020) Andrea Angeli et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Tellurides Bearing Sulfonamides as Novel Inhibitors of Leishmanial Carbonic Anhydrase with Potent Antileishmanial Activity

(2020) Andrea Angeli et al.   JOURNAL OF MEDICINAL CHEMISTRY

Progress in the development of human carbonic anhydrase inhibitors and their pharmacological applications: Where are we today?

(2020) Chandra B. Mishra et al.   MEDICINAL RESEARCH REVIEWS

Life cycle maintenance and drug-sensitivity assays for early drug discovery in Schistosoma mansoni

(2019) Flavio C. Lombardo et al.   Nature Protocols

A structure-based approach towards the identification of novel antichagasic compounds: Trypanosoma cruzi carbonic anhydrase inhibitors

(2019) Manuel A. Llanos et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Anticancer effects of new dibenzenesulfonamides by inducing apoptosis and autophagy pathways and their carbonic anhydrase inhibitory effects on hCA I, hCA II, hCA IX, hCA XII isoenzymes

(2018) Halise Inci Gul et al.   BIOORGANIC CHEMISTRY

Design, synthesis and X-ray crystallography of selenides bearing benzenesulfonamide moiety with neuropathic pain modulating effects

(2018) Andrea Angeli et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antischistosomal agents: state of art and perspectives

(2018) Eloi M Lago et al.   Future Medicinal Chemistry

The mechanism of action of praziquantel: can new drugs exploit similar mechanisms?

(2018) Charlotte M. Thomas et al.   CURRENT MEDICINAL CHEMISTRY

Schistosomiasis

(2018) Donald P. McManus et al.   Nature Reviews Disease Primers

Structure and function of carbonic anhydrases

(2016) C. T. Supuran   BIOCHEMICAL JOURNAL

Schistosomiasis and its treatment

(2015) Conor R Caffrey   Future Medicinal Chemistry

Human Schistosomiasis: Clinical Perspective: Review

(2013) Rashad S. Barsoum et al.   Journal of Advanced Research

Susceptibility or resistance of praziquantel in human schistosomiasis: a review

(2012) Wei Wang et al.   PARASITOLOGY RESEARCH

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Schistosomiasis elimination: lessons from the past guide the future

(2010) Darren J Gray et al.   LANCET INFECTIOUS DISEASES

Reduced Susceptibility to Praziquantel among Naturally Occurring Kenyan Isolates of Schistosoma mansoni

(2009) Sandra D. Melman et al.   PLoS Neglected Tropical Diseases

Taste, A New Incentive to Switch to (R)-Praziquantel in Schistosomiasis Treatment

(2009) Thorsten Meyer et al.   PLoS Neglected Tropical Diseases

Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis

(2008) Michael J Doenhoff et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

(2008) Claudiu T. Supuran   NATURE REVIEWS DRUG DISCOVERY