Article
Food Science & Technology
Ji Hyeon Kim, Hyunwoo Ahn, Daehyeop Lee, Hyunjun Lee, Wang June Kim
Summary: This study investigated the potential of the JM01 bacteriocin produced by Pediococcus acidilactici JM01 as an effective antibiofilm agent for MRSA. Results showed that JM01 bacteriocin significantly reduced MRSA biofilm formation by inhibiting its growth and adhesion. Therefore, JM01 bacteriocin could be a potential candidate for regulating biofilm formation by MRSA.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Food Science & Technology
Hong-Wei Li, Yi-Zhou Xiang, Man Zhang, Yu-Hang Jiang, Yao Zhang, Ying-Yang Liu, Lian-Bing Lin, Qi-Lin Zhang
Summary: The study identified a novel bacteriocin XJS01 with potential activity against foodborne Staphylococcus aureus. XJS01 exhibited low minimum inhibitory concentration and good resistance to heat treatment, leading to significant inhibition of both planktonic cells and biofilm formation of S. aureus. The bacteriocin impaired membrane permeability, caused cytoplasmic content leakage, and induced cell deformation in S. aureus.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Immunology
Abderrahmen Merghni, Mohamed Ali Lassoued, Bakoliarisoa Nivomalala Voahangy Rasoanirina, Sarra Moumni, Maha Mastouri
Summary: This study analyzed the chemical composition of turpentine essential oil and developed a nanoemulsion with enhanced antibacterial and antibiofilm potential against MRSA. The nanoemulsion showed promising biofilm disruption activity.
MICROBIAL PATHOGENESIS
(2022)
Article
Biochemistry & Molecular Biology
Yi-Zhou Xiang, Gang Wu, Lin-Yu Yang, Xiao-Jie Yang, Yan-Mei Zhang, Lian-Bing Lin, Xian-Yu Deng, Qi-Lin Zhang
Summary: The study evaluated the antibacterial effect of bacteriocin XJS01 against multidrug-resistant Staphylococcus aureus biofilms and its potential as an antibiofilm agent. Results showed that XJS01 exhibited excellent therapeutic effect, effectively disrupting and reducing biofilms on mouse skin wounds.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Microbiology
Shu Liu, Shulin Deng, Hualin Liu, Liang Tang, Mengqi Wang, Bingyue Xin, Feng Li
Summary: This study identified four novel leaderless bacteriocins, bacin A1, A2, A3, and A4, in Bacillus sp. TL12, which demonstrated potent bactericidal activity against S. aureus and MRSA. Additionally, bacins inhibited biofilm formation and killed cells in established biofilms of S. aureus and MRSA. These findings suggest that bacins have promising potential as alternative antimicrobial agents for treating MRSA infections.
MICROBIOLOGY SPECTRUM
(2022)
Article
Infectious Diseases
Vyacheslav M. Abramov, Igor V. Kosarev, Andrey V. Machulin, Tatiana V. Priputnevich, Evgenia I. Deryusheva, Ekaterina L. Nemashkalova, Irina O. Chikileva, Tatiana N. Abashina, Alexander N. Panin, Vyacheslav G. Melnikov, Nataliya E. Suzina, Ilia N. Nikonov, Marina V. Selina, Valentin S. Khlebnikov, Vadim K. Sakulin, Vladimir A. Samoilenko, Alexey B. Gordeev, Gennady T. Sukhikh, Vladimir N. Uversky, Andrey V. Karlyshev
Summary: LF3872 strain from a lactating woman produces a thermolabile class III bacteriolysin (BLF3872) that exhibits antimicrobial activity against antibiotic-resistant Staphylococcus aureus strains. The study is important for developing new drugs against antibiotic-resistant S. aureus strains circulating in both human and animal environments.
Article
Acoustics
Qin Shu, Hanghang Lou, Tianyu Wei, Xinglin Zhang, Qihe Chen
Summary: The synergistic treatment of ultrasound and MEL-A showed remarkable antibacterial effect against MRSA, as evidenced by enumeration of viable microbes.
ULTRASONICS SONOCHEMISTRY
(2021)
Article
Infectious Diseases
Libardo Suarez, Andres Pereira, William Hidalgo, Nelson Uribe
Summary: The semi-purified fractions from the mucus secretion of Achatina fulica showed inhibition of growth and biofilm formation of Staphylococcus aureus, as well as affecting the activity of virulence factors produced by the bacteria.
Article
Biochemistry & Molecular Biology
Xiuchuan Tan, Shenghong Xie, Xiao Jin, Ruiying Zhu, Shuangshuang Wei, Yanting Song, Xi Xie, Rong Wang, Lushuang Li, Manchuriga Wang, Yingxia Zhang
Summary: Peptides derived from Temporin-GHa cloned from Hylarana guentheri show potent antimicrobial activities against methicillin-resistant Staphylococcus aureus (MRSA) by damaging the bacterial membrane and inhibiting biofilm formation, with low toxicity to human erythrocytes.
ACTA BIOCHIMICA ET BIOPHYSICA SINICA
(2022)
Article
Food Science & Technology
Simona Lencova, Kamila Zdenkova, Katerina Demnerova, Hana Stiborova
Summary: The study compared the antibacterial and antibiofilm effects of seven natural-origin additives, with citric acid, garlic extract, and erythorbic acid being identified as the most effective. Furthermore, mixtures of garlic extract with other additives showed synergy in bacterial suppression, even against E. coli.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Microbiology
Yunfeng Xu, Weiping Guo, Denglin Luo, Peiyan Li, Jinle Xiang, Junliang Chen, Xiaodong Xia, Qinggang Xie
Summary: This study aimed to investigate the antibiofilm effects of punicalagin against Staphylococcus aureus. The results showed that punicalagin significantly reduced the biomass and metabolic activity of biofilms, decreased the number of viable cells, and damaged the structure of biofilms. The antibiofilm mechanism partly involved the modification of cell surface hydrophobicity. These findings suggest that punicalagin has the potential to be developed as an alternative to control S. aureus biofilms.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
Zhu Qiao, Jiaxin Chen, Qiaqia Zhou, Xin Wang, Yuanyuan Shan, Yanglei Yi, Bianfang Liu, Yuan Zhou, Xin Lu
Summary: Bacteriocin BM173 was successfully expressed and purified, showing broad-spectrum antibacterial activity, high thermal and pH stability, as well as efficacy in disrupting cell membrane integrity and inhibiting biofilm formation. These findings suggest that BM173 has promising potential as a preservative in the dairy industry.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Food Science & Technology
Jian-Ping Ying, Gang Wu, Yan-Mei Zhang, Qi-Lin Zhang
Summary: The proteomic mechanism of Lactobacillus salivarius bacteriocin XJS01 against foodborne S. aureus and its preservation effect on raw pork loins were investigated. XJS01 induced a complex organism response in S. aureus and showed potential as a pork preservative.
Article
Food Science & Technology
Weiping Guo, Yunfeng Xu, Yangyang Yang, Jinle Xiang, Junliang Chen, Denglin Luo, Qinggang Xie
Summary: Oleuropein has the potential to inhibit the formation of Staphylococcus aureus biofilm and reduce bacterial viability.
Article
Food Science & Technology
Wei-Gang Xin, Gang Wu, Jian-Ping Ying, Yi-Zhou Xiang, Yu-Hang Jiang, Xian-Yu Deng, Lian-Bing Lin, Qi-Lin Zhang
Summary: This study investigated the antibacterial activity and mechanism of action of bacteriocin LFX01 against two important indicator strains that cause pork contamination. The results showed that LFX01 exhibited antibacterial activity against these indicator strains by reducing cell metabolic activity, disrupting cell membrane integrity, and causing leakage of intracellular contents. Additionally, LFX01 was found to bind to the genomic DNA of the indicator strains, disrupting its structure. These findings revealed the mechanism of action of LFX01 against the indicator strains.
Article
Biochemistry & Molecular Biology
Yi-Zhou Xiang, Gang Wu, Lin-Yu Yang, Xiao-Jie Yang, Yan-Mei Zhang, Lian-Bing Lin, Xian-Yu Deng, Qi-Lin Zhang
Summary: The study evaluated the antibacterial effect of bacteriocin XJS01 against multidrug-resistant Staphylococcus aureus biofilms and its potential as an antibiofilm agent. Results showed that XJS01 exhibited excellent therapeutic effect, effectively disrupting and reducing biofilms on mouse skin wounds.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Food Science & Technology
Yu-Hang Jiang, Lin-Yu Yang, Wei-Gang Xin, Qi-Lin Zhang
Summary: The study found that the combined use of PLA and XJS01 had a better antibacterial and antibiofilm activity against Shigella flexneri_14 compared to when used individually.
Article
Food Science & Technology
Yi-Zhou Xiang, Gang Wu, Yi-Ping Zhang, Lin-Yu Yang, Yan-Mei Zhang, Zi-Shun Zhao, Xian-Yu Deng, Qi-Lin Zhang
Summary: A new bacteriocin, RSQ04, showed inhibitory effects on Listeria monocytogenes and its biofilms with excellent stability under adverse conditions. RSQ04 disrupted the cellular structure of L. monocytogenes and exhibited antibiofilm activity. This study systematically investigated the purification, characterization, safety assessment, and practical application of RSQ04, providing insights for the development and utilization of bacteriocins in the food industry.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Entomology
Xiao-Jie Yang, Zi-Shun Zhao, Yan-Mei Zhang, Jian-Ping Ying, Su-Hao Wang, Ming-Long Yuan, Qi-Lin Zhang
Summary: This study presents a method for isolating highly purified and active mitochondria from insects. The method combines differential centrifugation and discontinuous Nycodenz density gradient centrifugation and has been validated across three orders and four insect species. The study demonstrates the removal of nonmitochondrial components and the preservation of mitochondria activity/integrity. It also highlights the importance of storing the isolated mitochondria at -20 degrees C for downstream experiments.
JOURNAL OF INSECT PHYSIOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Yu-Hang Jiang, Jian-Ping Ying, Wei-Gang Xin, Lin-Yu Yang, Xiu-Zhang Li, Qi-Lin Zhang
Summary: This study demonstrates the antibacterial activity of phenyllactic acid (PLA) against Staphylococcus aureus and its potential application in dairy products. PLA inhibits the growth and biofilm formation of S. aureus, and it exerts antibacterial effects by affecting the cell metabolism, membrane integrity, intracellular content leakage, oxidative stress, and morphological deformation of S. aureus. The antibacterial effects of PLA against S. aureus cells in skim milk and cheese are maintained during storage for 21 days at 4 degrees C.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Entomology
Linyu Yang, Zishun Zhao, Dan Luo, Mingzhong Liang, Qilin Zhang
Summary: By studying the metabolomes of Aquatica leii and Lychnuris praetexta, we found that aquatic fireflies exhibit changes in metabolites and pathways related to freshwater adaptation, including oxidative stress, immunity response, energy metabolism, and sense function.
Article
Food Science & Technology
Wei-Gang Xin, Gang Wu, Jian-Ping Ying, Yi-Zhou Xiang, Yu-Hang Jiang, Xian-Yu Deng, Lian-Bing Lin, Qi-Lin Zhang
Summary: This study investigated the antibacterial activity and mechanism of action of bacteriocin LFX01 against two important indicator strains that cause pork contamination. The results showed that LFX01 exhibited antibacterial activity against these indicator strains by reducing cell metabolic activity, disrupting cell membrane integrity, and causing leakage of intracellular contents. Additionally, LFX01 was found to bind to the genomic DNA of the indicator strains, disrupting its structure. These findings revealed the mechanism of action of LFX01 against the indicator strains.
Article
Entomology
Lin-Yu Yang, Xiao-Jie Yang, Zi-Shun Zhao, Qi-Lin Zhang
Summary: This study investigated the effects of the pesticide abamectin on mitochondrial energy metabolism using metabolomic analysis of isolated mitochondria from German cockroaches. The results showed abnormal mitochondrial morphology and changes in key enzyme activities involved in energy metabolism under abamectin stress. Metabolomic analysis revealed a set of metabolites and pathways related to mitochondrial energy metabolism. This study provides valuable insights into mitochondrial toxicology at a subcellular level under environmental toxicants.