The Anti-Atherosclerosis Effect of Anakinra, a Recombinant Human Interleukin-1 Receptor Antagonist, in Apolipoprotein E Knockout Mice

Interleukin‐1 Blockade Inhibits the Acute Inflammatory Response in Patients With ST‐Segment–Elevation Myocardial Infarction

(2020) Antonio Abbate et al.   Journal of the American Heart Association

Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease

(2020) Antonio Abbate et al.   CIRCULATION RESEARCH

Targeting IL-1β in the Treatment of Atherosclerosis

(2020) Wuqian Mai et al.   Frontiers in Immunology

Stage-dependent differential effects of interleukin-1 isoforms on experimental atherosclerosis

(2019) Amélie Vromman et al.   EUROPEAN HEART JOURNAL

Macrophage Death as a Pharmacological Target in Atherosclerosis

(2019) Wim Martinet et al.   Frontiers in Pharmacology

Atherosclerosis

(2019) Peter Libby et al.   Nature Reviews Disease Primers

OUP accepted manuscript

(2018)   EUROPEAN HEART JOURNAL

Interleukin-1β has atheroprotective effects in advanced atherosclerotic lesions of mice

(2018) Delphine Gomez et al.   NATURE MEDICINE

Use of Interleukin-1 Blockers in Pericardial and Cardiovascular Diseases

(2018) Giacomo Emmi et al.   Current Cardiology Reports

Hexim1 heterozygosity stabilizes atherosclerotic plaque and decreased steatosis in ApoE null mice fed atherogenic diet

(2017) Manya Dhar-Mascareno et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

(2017) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

The central role of arterial retention of cholesterol-rich apolipoprotein-B-containing lipoproteins in the pathogenesis of atherosclerosis

(2016) Jan Borén et al.   CURRENT OPINION IN LIPIDOLOGY

Interleukin-1 Blockade in Acute Decompensated Heart Failure

(2016) Benjamin W. Van Tassell et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Long-term safety profile of anakinra in patients with severe cryopyrin-associated periodic syndromes

(2016) Torbjörn Kullenberg et al.   RHEUMATOLOGY

The interleukin-1 receptor antagonist anakinra improves endothelial dysfunction in streptozotocin-induced diabetic rats

(2014) Susana Vallejo et al.   Cardiovascular Diabetology

Adipose Tissue Immune Response: Novel Triggers and Consequences for Chronic Inflammatory Conditions

(2014) Giorgio Ghigliotti et al.   INFLAMMATION

Palmitate-Stimulated Monocytes Induce Adhesion Molecule Expression in Endothelial Cells via IL-1 Signaling Pathway

(2014) Yosuke Shikama et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Effects of Interleukin-1 Blockade With Anakinra on Aerobic Exercise Capacity in Patients With Heart Failure and Preserved Ejection Fraction (from the D-HART Pilot Study)

(2013) Benjamin Wallace Van Tassell et al.   AMERICAN JOURNAL OF CARDIOLOGY

Targeting Interleukin-1 in Heart Disease

(2013) Benjamin W. Van Tassell et al.   CIRCULATION

Effects of Interleukin-1β Inhibition With Canakinumab on Hemoglobin A1c, Lipids, C-Reactive Protein, Interleukin-6, and Fibrinogen

(2012) Paul M Ridker et al.   CIRCULATION

Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

(2012) Charles A. Dinarello et al.   NATURE REVIEWS DRUG DISCOVERY

DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson’s disease

(2011) Xinglong Wang et al.   AGING CELL

Monoclonal antibodies targeting IL-1 beta reduce biomarkers of atherosclerosis in vitro and inhibit atherosclerotic plaque formation in Apolipoprotein E-deficient mice

(2011) Vinay Bhaskar et al.   ATHEROSCLEROSIS

Treatment with Anakinra Improves Disposition Index But Not Insulin Sensitivity in Nondiabetic Subjects with the Metabolic Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study

(2011) Edwin J. P. van Asseldonk et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Association of Lipidome Remodeling in the Adipocyte Membrane with Acquired Obesity in Humans

(2011) Kirsi H. Pietiläinen et al.   PLOS BIOLOGY

Interleukin-1 (IL-1) Pathway

(2010) A. Weber et al.   Science Signaling

Inhibition of Interleukin-1 by Anakinra Improves Vascular and Left Ventricular Function in Patients With Rheumatoid Arthritis

(2008) Ignatios Ikonomidis et al.   CIRCULATION

Anakinra, a Recombinant Human Interleukin-1 Receptor Antagonist, Inhibits Apoptosis in Experimental Acute Myocardial Infarction

(2008) Antonio Abbate et al.   CIRCULATION