Novel reversible selective inhibitor of nuclear export shows that CRM1 is a target in colorectal cancer cells

Selective inhibitors of nuclear export (SINE) as novel therapeutics for prostate cancer

(2015) Janet Mendonca et al.   Oncotarget

Chk1-induced CCNB1 overexpression promotes cell proliferation and tumor growth in human colorectal cancer

(2014) Yifeng Fang et al.   CANCER BIOLOGY & THERAPY

Characterization of rare transformingKRASmutations in sporadic colorectal cancer

(2014) Joanna HM Tong et al.   CANCER BIOLOGY & THERAPY

The cyclin D1-CDK4 oncogenic interactome enables identification of potential novel oncogenes and clinical prognosis

(2014) Siwanon Jirawatnotai et al.   CELL CYCLE

Nuclear Trafficking in Health and Disease

(2014) Amir Mor et al.   CURRENT OPINION IN CELL BIOLOGY

Reality Check for Pemetrexed and Maintenance Therapy in Advanced Non–Small-Cell Lung Cancer

(2014) Nevin Murray   JOURNAL OF CLINICAL ONCOLOGY

Selective inhibitors of nuclear export (SINE)– a novel class of anti-cancer agents

(2014) Kaushal Parikh et al.   Journal of Hematology & Oncology

Plumbagin induces growth inhibition of human glioma cells by downregulating the expression and activity of FOXM1

(2014) Xuejiao Liu et al.   JOURNAL OF NEURO-ONCOLOGY

CRM1 Is a Direct Cellular Target of the Natural Anti-cancer Agent Plumbagin

(2014) Xuejiao Liu et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Inhibition of CRM1-dependent nuclear export sensitizes malignant cells to cytotoxic and targeted agents

(2014) Joel G. Turner et al.   SEMINARS IN CANCER BIOLOGY

Clinical translation of nuclear export inhibitors in cancer

(2014) William T. Senapedis et al.   SEMINARS IN CANCER BIOLOGY

Promising SINEs for Embargoing Nuclear-Cytoplasmic Export as an Anticancer Strategy

(2014) D. S. P. Tan et al.   Cancer Discovery

Mutant p53 Prolongs NF-κB Activation and Promotes Chronic Inflammation and Inflammation-Associated Colorectal Cancer

(2013) Tomer Cooks et al.   CANCER CELL

Knockdown of CRM1 inhibits the nuclear export of p27Kip1 phosphorylated at serine 10 and plays a role in the pathogenesis of epithelial ovarian cancer

(2013) You Wang et al.   CANCER LETTERS

Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1

(2013) Qingxiang Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel selective inhibitors of nuclear export CRM1 antagonists for therapy in mantle cell lymphoma

(2012) Kejie Zhang et al.   EXPERIMENTAL HEMATOLOGY

Tautomycetin Induces Apoptosis by Inactivating Akt Through a PP1-Independent Signaling Pathway in Human Breast Cancer Cells

(2012) Mingshan Niu et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Cytoreductive surgery plus hyperthermic perioperative chemotherapy to treat peritoneal metastases from colorectal cancer: standard of care or an experimental approach?

(2012) Paul H Sugarbaker et al.   LANCET ONCOLOGY

Nuclear export of proteins and drug resistance in cancer

(2011) Joel G. Turner et al.   BIOCHEMICAL PHARMACOLOGY

CBS9106 is a novel reversible oral CRM1 inhibitor with CRM1 degrading activity

(2011) K. Sakakibara et al.   BLOOD

Quinacrine synergizes with 5-fluorouracil and other therapies in colorectal cancer

(2011) Jean-Nicolas Gallant et al.   CANCER BIOLOGY & THERAPY

The Anti-inflammatory Prostaglandin 15-Deoxy-Δ12,14-PGJ2Inhibits CRM1-dependent Nuclear Protein Export

(2010) Mark Hilliard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

EXPRESSION OF CRM1 IN HUMAN GLIOMAS AND ITS SIGNIFICANCE IN P27 EXPRESSION AND CLINICAL PROGNOSIS

(2009) Aiguo Shen et al.   NEUROSURGERY