Nanomedicine as an emerging platform for metastatic lung cancer therapy

Localized RNAi Therapeutics of Chemoresistant Grade IV Glioma Using Hyaluronan-Grafted Lipid-Based Nanoparticles

(2015) Zvi R. Cohen et al.   ACS Nano

Targeting the invasive phenotype of cisplatin-resistant Non-Small Cell Lung Cancer cells by a novel histone deacetylase inhibitor

(2015) Valentina Zuco et al.   BIOCHEMICAL PHARMACOLOGY

Hepatocyte-Specific Delivery of siRNAs Conjugated to Novel Non-nucleosidic TrivalentN-Acetylgalactosamine Elicits Robust Gene Silencing in Vivo

(2015) Kallanthottathil G. Rajeev et al.   CHEMBIOCHEM

Solid lipid nanoparticles as nucleic acid delivery system: Properties and molecular mechanisms

(2015) Marcelo B. de Jesus et al.   JOURNAL OF CONTROLLED RELEASE

siRNA delivery to lung-metastasized tumor by systemic injection with cationic liposomes

(2015) Yoshiyuki Hattori et al.   JOURNAL OF LIPOSOME RESEARCH

Patterns of relapse in extrapulmonary small cell carcinoma: retrospective analysis of outcomes from two cancer centres

(2015) S. Gennatas et al.   BMJ Open

Nanoparticles for Imaging, Sensing, and Therapeutic Intervention

(2014) Lara K. Bogart et al.   ACS Nano

Delivery of platinum(IV) drug to subcutaneous tumor and lung metastasis using bradykinin-potentiating peptide-decorated chitosan nanoparticles

(2014) Xin Wang et al.   BIOMATERIALS

Selective eradication of tumor vascular pericytes by peptide-conjugated nanoparticles for antiangiogenic therapy of melanoma lung metastasis

(2014) Ying-Yun Guan et al.   BIOMATERIALS

Immune regulation of therapy-resistant niches: emerging targets for improving anticancer drug responses

(2014) Masahisa Jinushi   CANCER AND METASTASIS REVIEWS

Modulating cancer multidrug resistance by sertraline in combination with a nanomedicine

(2014) Velthe Drinberg et al.   CANCER LETTERS

Overcoming multidrug resistance with nanomedicines

(2014) Assaf Ganoth et al.   Expert Opinion on Drug Delivery

Anticancer polymeric nanomedicine bearing synergistic drug combination is superior to a mixture of individually-conjugated drugs

(2014) Ela Markovsky et al.   JOURNAL OF CONTROLLED RELEASE

Enhanced antitumor and anti-metastasis efficiency via combined treatment with CXCR4 antagonist and liposomal doxorubicin

(2014) Ling Mei et al.   JOURNAL OF CONTROLLED RELEASE

Polymer therapeutics: Top 10 selling pharmaceuticals — What next?

(2014) Ruth Duncan   JOURNAL OF CONTROLLED RELEASE

Endosomal Escape: A Bottleneck in Intracellular Delivery

(2014) Harshad K. Shete et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Tumor targeting profiling of hyaluronan-coated lipid based-nanoparticles

(2014) Shoshy Mizrahy et al.   Nanoscale

A unique squalenoylated and nonpegylated doxorubicin nanomedicine with systemic long-circulating properties and anticancer activity

(2014) A. Maksimenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aberrant Glycosylation Promotes Lung Cancer Metastasis through Adhesion to Galectins in the Metastatic Niche

(2014) Nathan E. Reticker-Flynn et al.   Cancer Discovery

Improving Conventional Enhanced Permeability and Retention (EPR) Effects; What Is the Appropriate Target?

(2014) Hisataka Kobayashi et al.   Theranostics

End-binding protein 1 stimulates paclitaxel sensitivity in breast cancer by promoting its actions toward microtubule assembly and stability

(2014) Youguang Luo et al.   Protein & Cell

Lipid Envelope-Type Nanoparticle Incorporating a Multifunctional Peptide for Systemic siRNA Delivery to the Pulmonary Endothelium

(2013) Kenji Kusumoto et al.   ACS Nano

A daunting task: manipulating leukocyte function with RNAi

(2013) Dan Peer   IMMUNOLOGICAL REVIEWS

Systemic delivery of sticky siRNAs targeting the cell cycle for lung tumor metastasis inhibition

(2013) Marie-Elise Bonnet et al.   JOURNAL OF CONTROLLED RELEASE

Systemically administered liposome-encapsulated Ad-PEDF potentiates the anti-cancer effects in mouse lung metastasis melanoma

(2013) Hua-shan Shi et al.   Journal of Translational Medicine

Intravenous Delivery of siRNA Targeting CD47 Effectively Inhibits Melanoma Tumor Growth and Lung Metastasis

(2013) Yuhua Wang et al.   MOLECULAR THERAPY

Complexation of Cell-Penetrating Peptide–Polymer Conjugates with Polyanions Controls Cells Uptake of HPMA Copolymers and Anti-tumor Activity

(2013) Yosi Shamay et al.   PHARMACEUTICAL RESEARCH

Intelligently Targeted Drug Delivery and Enhanced Antitumor Effect by Gelatinase-Responsive Nanoparticles

(2013) Rutian Li et al.   PLoS One

Extending Survival of Stage IV Non-Small Cell Lung Cancer

(2013) Simona Carnio et al.   SEMINARS IN ONCOLOGY

Toxicity profiling of several common RNAi-based nanomedicines: a comparative study

(2013) Dalit Landesman-Milo et al.   Drug Delivery and Translational Research

RNA interference-based therapeutics and diagnostics

(2013) Dan Peer et al.   Drug Delivery and Translational Research

Immunotoxicity derived from manipulating leukocytes with lipid-based nanoparticles

(2012) Dan Peer   ADVANCED DRUG DELIVERY REVIEWS

RNAi-based nanomedicines for targeted personalized therapy

(2012) Ala Daka et al.   ADVANCED DRUG DELIVERY REVIEWS

Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo

(2012) Muthusamy Jayaraman et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Simultaneous inhibition of metastasis and growth of breast cancer by co-delivery of twist shRNA and paclitaxel using pluronic P85-PEI/TPGS complex nanoparticles

(2012) Jianan Shen et al.   BIOMATERIALS

Inhibition of metastatic tumor formation in vivo by a bacteriophage display-derived galectin-3 targeting peptide

(2012) Jessica R. Newton-Northup et al.   CLINICAL & EXPERIMENTAL METASTASIS

Doxil® — The first FDA-approved nano-drug: Lessons learned

(2012) Yechezkel (Chezy) Barenholz   JOURNAL OF CONTROLLED RELEASE

Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA

(2012) Nathan M Belliveau et al.   Molecular Therapy-Nucleic Acids

Polysaccharides as building blocks for nanotherapeutics

(2011) Shoshy Mizrahy et al.   CHEMICAL SOCIETY REVIEWS

Special delivery: targeted therapy with small RNAs

(2011) D Peer et al.   GENE THERAPY

A Novel Paclitaxel Microemulsion Containing a Reduced Amount of Cremophor EL: Pharmacokinetics, Biodistribution, andIn VivoAntitumor Efficacy and Safety

(2011) Ying Wang et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Altering the immune response with lipid-based nanoparticles

(2011) Dalit Landesman-Milo et al.   JOURNAL OF CONTROLLED RELEASE

Grand challenges in modulating the immune response with RNAi nanomedicines

(2011) Meir Goldsmith et al.   Nanomedicine

The systemic toxicity of positively charged lipid nanoparticles and the role of Toll-like receptor 4 in immune activation

(2010) Ranit Kedmi et al.   BIOMATERIALS

Aerosol Delivery of Liposomal Formulated Paclitaxel and Vitamin E Analog Reduces Murine Mammary Tumor Burden and Metastases

(2009) Paul Latimer et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Phase II studies of polymer-doxorubicin (PK1, FCE28068) in the treatment of breast, lung and colorectal cancer

(2009) Seymour   INTERNATIONAL JOURNAL OF ONCOLOGY

Apoptosis-Inducing High.NO Concentrations Are Not Sustained Either in Nascent or in Developed Cancers

(2008) Adam Heller   ChemMedChem

Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect

(2008) H. Maeda et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Tumor-Specific Anti-Nucleosome Antibody Improves Therapeutic Efficacy of Doxorubicin-Loaded Long-Circulating Liposomes against Primary and Metastatic Tumor in Mice

(2008) Tamer A. ElBayoumi et al.   MOLECULAR PHARMACEUTICS

Efficient gene silencing in metastatic tumor by siRNA formulated in surface-modified nanoparticles

(2007) Shyh-Dar Li et al.   JOURNAL OF CONTROLLED RELEASE