Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis

Dietary excess regulates absorption and surface of gut epithelium through intestinal PPARα

(2021) Ozren Stojanović et al.   Nature Communications

Regulation of intestinal lipid metabolism: current concepts and relevance to disease

(2020) Chih-Wei Ko et al.   Nature Reviews Gastroenterology & Hepatology

Bariatric Surgery Provides Long-term Resolution of Nonalcoholic Steatohepatitis and Regression of Fibrosis

(2020) Guillaume Lassailly et al.   GASTROENTEROLOGY

Benefits and Risks of Bariatric Surgery in Adults

(2020) David E. Arterburn et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Global epidemiology of NAFLD-related HCC: trends, predictions, risk factors and prevention

(2020) Daniel Q. Huang et al.   Nature Reviews Gastroenterology & Hepatology

Intestinal PPARα Protects Against Colon Carcinogenesis via Regulation of Methyltransferases DNMT1 and PRMT6

(2019) Yuhong Luo et al.   GASTROENTEROLOGY

Hepatocyte peroxisome proliferator-activated receptor α regulates bile acid synthesis and transport

(2019) Cen Xie et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Extrahepatic PPARα modulates fatty acid oxidation and attenuates fasting-induced hepatosteatosis in mice

(2018) Chad N. Brocker et al.   JOURNAL OF LIPID RESEARCH

Hepatocyte and stellate cell deletion of liver fatty acid binding protein reveals distinct roles in fibrogenic injury

(2018) Elizabeth P. Newberry et al.   FASEB JOURNAL

Non-alcoholic fatty liver disease – A global public health perspective

(2018) Zobair M. Younossi   JOURNAL OF HEPATOLOGY

Hepatocyte Peroxisome Proliferator–Activated Receptor α Enhances Liver Regeneration after Partial Hepatectomy in Mice

(2018) Guomin Xie et al.   AMERICAN JOURNAL OF PATHOLOGY

PPAR-α agonists are still on the rise: an update on clinical and experimental findings

(2017) Nicola Ferri et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Current and upcoming pharmacotherapy for non-alcoholic fatty liver disease

(2016) Yaron Rotman et al.   GUT

Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD

(2016) Alexandra Montagner et al.   GUT

PPARs in obesity-induced T2DM, dyslipidaemia and NAFLD

(2016) Barbara Gross et al.   Nature Reviews Endocrinology

Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease

(2015) Michal Pawlak et al.   JOURNAL OF HEPATOLOGY

Recent insights into the biological functions of liver fatty acid binding protein 1

(2015) GuQi Wang et al.   JOURNAL OF LIPID RESEARCH

Liver fatty acid binding protein (L-Fabp) modulates murine stellate cell activation and diet-induced nonalcoholic fatty liver disease

(2013) Anping Chen et al.   HEPATOLOGY

Direct Comparison of Mice Null for Liver or Intestinal Fatty Acid-binding Proteins Reveals Highly Divergent Phenotypic Responses to High Fat Feeding

(2013) Angela M. Gajda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In vivoimaging reveals selective PPAR activity in the skin of peroxisome proliferator-activated receptor responsive element-luciferase reporter mice

(2012) Noura El-Jamal et al.   EXPERIMENTAL DERMATOLOGY

Decreased body weight and hepatic steatosis with altered fatty acid ethanolamide metabolism in agedL-Fabp−/−mice

(2012) Elizabeth P. Newberry et al.   JOURNAL OF LIPID RESEARCH

Fibrates in the Treatment of Dyslipidemias — Time for a Reassessment

(2011) Allison B. Goldfine et al.   NEW ENGLAND JOURNAL OF MEDICINE

Diet-induced obesity and hepatic steatosis in L-Fabp−/− mice is abrogated with SF, but not PUFA, feeding and attenuated after cholesterol supplementation

(2007) Elizabeth P. Newberry et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY