标题
Regulation of intestinal lipid metabolism: current concepts and relevance to disease
作者
关键词
-
出版物
Nature Reviews Gastroenterology & Hepatology
Volume 17, Issue 3, Pages 169-183
出版商
Springer Science and Business Media LLC
发表日期
2020-02-03
DOI
10.1038/s41575-019-0250-7
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Chylomicron retention disease
- (2019) Emile Levy et al. CURRENT OPINION IN LIPIDOLOGY
- Cholesterol trafficking and raft-like membrane domain composition mediate scavenger receptor class B type 1-dependent lipid sensing in intestinal epithelial cells
- (2018) Etienne Morel et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Small Intestine Microbiota Regulate Host Digestive and Absorptive Adaptive Responses to Dietary Lipids
- (2018) Kristina Martinez-Guryn et al. Cell Host & Microbe
- Intestinal Failure and Aberrant Lipid Metabolism in Patients With DGAT1 Deficiency
- (2018) Jorik M. van Rijn et al. GASTROENTEROLOGY
- Recent Advances in Triacylglycerol Mobilization by the Gut
- (2018) Changting Xiao et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- NPC1L1-dependent intestinal cholesterol absorption requires ganglioside GM3 in membrane microdomains
- (2018) Wataru Nihei et al. JOURNAL OF LIPID RESEARCH
- Vitamin E intestinal absorption: Regulation of membrane transport across the enterocyte
- (2018) Emmanuelle Reboul IUBMB LIFE
- Intestinal Farnesoid X Receptor Controls Transintestinal Cholesterol Excretion in Mice
- (2017) Jan Freark de Boer et al. GASTROENTEROLOGY
- Using primary murine intestinal enteroids to study dietary TAG absorption, lipoprotein synthesis, and the role of apoC-III in the intestine
- (2017) Javeed Jattan et al. JOURNAL OF LIPID RESEARCH
- Perilipins: a diversity of intracellular lipid droplet proteins
- (2017) Hiroyuki Itabe et al. Lipids in Health and Disease
- Circulating Apolipoprotein A-IV presurgical levels are associated with improvement in insulin sensitivity after Roux-en-Y gastric bypass surgery
- (2017) Raghavendra Rao et al. Surgery for Obesity and Related Diseases
- Biochemical characterization of human acyl coenzyme A: 2-monoacylglycerol acyltransferase-3 (MGAT3)
- (2016) Curtis Brandt et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Recent discoveries on absorption of dietary fat: Presence, synthesis, and metabolism of cytoplasmic lipid droplets within enterocytes
- (2016) Theresa D'Aquila et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Transintestinal Cholesterol Transport Is Active in Mice and Humans and Controls Ezetimibe-Induced Fecal Neutral Sterol Excretion
- (2016) Lily Jakulj et al. Cell Metabolism
- Characteristics and functions of lipid droplets and associated proteins in enterocytes
- (2016) Frauke Beilstein et al. EXPERIMENTAL CELL RESEARCH
- Antibiotics Suppress Activation of Intestinal Mucosal Mast Cells and Reduce Dietary Lipid Absorption in Sprague-Dawley Rats
- (2016) Hirokazu Sato et al. GASTROENTEROLOGY
- Small Intestine but Not Liver Lysophosphatidylcholine Acyltransferase 3 (Lpcat3) Deficiency Has a Dominant Effect on Plasma Lipid Metabolism
- (2016) Inamul Kabir et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ezetimibe-sensitive cholesterol uptake by NPC1L1 protein does not require endocytosis
- (2016) Tory A. Johnson et al. MOLECULAR BIOLOGY OF THE CELL
- Exposure to dietary lipid leads to rapid production of cytosolic lipid droplets near the brush border membrane
- (2016) Zeina Soayfane et al. Nutrition & Metabolism
- Intestinal scavenger receptor class B type I as a novel regulator of chylomicron production in healthy and diet-induced obese states
- (2015) Marsel Lino et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- JTP-103237, a novel monoacylglycerol acyltransferase inhibitor, modulates fat absorption and prevents diet-induced obesity
- (2015) Chihiro Okuma et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Deficiency in Lysophosphatidylcholine Acyltransferase 3 Reduces Plasma Levels of Lipids by Reducing Lipid Absorption in Mice
- (2015) Zhiqiang Li et al. GASTROENTEROLOGY
- Dietary and biliary phosphatidylcholine activates PKCζ in rat intestine
- (2015) Shahzad Siddiqi et al. JOURNAL OF LIPID RESEARCH
- Gut biogeography of the bacterial microbiota
- (2015) Gregory P. Donaldson et al. NATURE REVIEWS MICROBIOLOGY
- A new model of reverse cholesterol transport: enTICEing strategies to stimulate intestinal cholesterol excretion
- (2015) Ryan E. Temel et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Lpcat3-dependent production of arachidonoyl phospholipids is a key determinant of triglyceride secretion
- (2015) Xin Rong et al. eLife
- Characterization of Zebrafish Green Cone Photoresponse Recorded with Pressure-Polished Patch Pipettes, Yielding Efficient Intracellular Dialysis
- (2015) Marco Aquila et al. PLoS One
- Lipid droplet biogenesis
- (2014) Florian Wilfling et al. CURRENT OPINION IN CELL BIOLOGY
- Intestinal lipid absorption and lipoprotein formation
- (2014) M. Mahmood Hussain CURRENT OPINION IN LIPIDOLOGY
- Hypobetalipoproteinemia and abetalipoproteinemia
- (2014) Francine K. Welty CURRENT OPINION IN LIPIDOLOGY
- Potential Effects of NPC1L1 Polymorphisms in Protecting against Clinical Disease in a Chinese Family with Sitosterolaemia
- (2014) Miao Hu et al. Journal of Atherosclerosis and Thrombosis
- Intestine-specific Deletion of Acyl-CoA:Monoacylglycerol Acyltransferase (MGAT) 2 Protects Mice from Diet-induced Obesity and Glucose Intolerance
- (2014) David W. Nelson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Relative roles ofABCG5/ABCG8in liver and intestine
- (2014) Jin Wang et al. JOURNAL OF LIPID RESEARCH
- Intestine-specific MTP and global ACAT2 deficiency lowers acute cholesterol absorption with chylomicrons and HDLs
- (2014) Jahangir Iqbal et al. JOURNAL OF LIPID RESEARCH
- NPC1L1 mutations lower CHD risk
- (2014) Tim Geach Nature Reviews Cardiology
- Inactivating Mutations in NPC1L1 and Protection from Coronary Heart Disease
- (2014) NEW ENGLAND JOURNAL OF MEDICINE
- Is apolipoprotein A-IV rate limiting in the intestinal transport and absorption of triglyceride?
- (2013) Alison B. Kohan et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Intestinal caveolin-1 is important for dietary fatty acid absorption
- (2013) Shahzad Siddiqi et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Triglyceride-rich lipoproteins and cytosolic lipid droplets in enterocytes: Key players in intestinal physiology and metabolic disorders
- (2013) Sylvie Demignot et al. BIOCHIMIE
- Defining the key pharmacophore elements of PF-04620110: Discovery of a potent, orally-active, neutral DGAT-1 inhibitor
- (2013) Robert L. Dow et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Lipid Absorption Defects in Intestine-specific Microsomal Triglyceride Transfer Protein and ATP-binding Cassette Transporter A1-deficient Mice
- (2013) Jahangir Iqbal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Apolipoprotein A-IV Reduces Hepatic Gluconeogenesis through Nuclear Receptor NR1D1
- (2013) Xiaoming Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Acyl-CoA synthetase 3 promotes lipid droplet biogenesis in ER microdomains
- (2013) Adam Kassan et al. JOURNAL OF CELL BIOLOGY
- Intestine-specific expression ofMOGAT2partially restores metabolic efficiency inMogat2-deficient mice
- (2013) Yu Gao et al. JOURNAL OF LIPID RESEARCH
- CD36 and SR-BI Are Involved in Cellular Uptake of Provitamin A Carotenoids by Caco-2 and HEK Cells, and Some of Their Genetic Variants Are Associated with Plasma Concentrations of These Micronutrients in Humans
- (2013) Patrick Borel et al. JOURNAL OF NUTRITION
- Autophagosomes contribute to intracellular lipid distribution in enterocytes
- (2013) Salem Ait Khaldoun et al. MOLECULAR BIOLOGY OF THE CELL
- The clathrin adaptor Numb regulates intestinal cholesterol absorption through dynamic interaction with NPC1L1
- (2013) Pei-Shan Li et al. NATURE MEDICINE
- Possible Role of Intestinal Fatty Acid Oxidation in the Eating-Inhibitory Effect of the PPAR-α Agonist Wy-14643 in High-Fat Diet Fed Rats
- (2013) Elnaz Karimian Azari et al. PLoS One
- Activation of rat intestinal mucosal mast cells by fat absorption
- (2012) Yong Ji et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Lumenal Lipid Metabolism
- (2012) Richard Lehner et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Apolipoprotein AIV Requires Cholecystokinin and Vagal Nerves to Suppress Food Intake
- (2012) Chunmin C. Lo et al. ENDOCRINOLOGY
- The gut microbiota elicits a profound metabolic reorientation in the mouse jejunal mucosa during conventionalisation
- (2012) Sahar El Aidy et al. GUT
- DGAT1 mutation is linked to a congenital diarrheal disorder
- (2012) Joel T. Haas et al. JOURNAL OF CLINICAL INVESTIGATION
- Adipose triglyceride lipase is a TG hydrolase of the small intestine and regulates intestinal PPARα signaling
- (2012) Sascha Obrowsky et al. JOURNAL OF LIPID RESEARCH
- Evidence for regulated monoacylglycerol acyltransferase expression and activity in human liver
- (2012) Angela M. Hall et al. JOURNAL OF LIPID RESEARCH
- Apolipoprotein A-IV improves glucose homeostasis by enhancing insulin secretion
- (2012) F. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Different functions of intestinal and liver-type fatty acid-binding proteins in intestine and in whole body energy homeostasis
- (2011) William Stacy Lagakos et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Intestinal SR-BI is upregulated in insulin-resistant states and is associated with overproduction of intestinal apoB48-containing lipoproteins
- (2011) Amanda A. Hayashi et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Apolipoprotein A-IV regulates chylomicron metabolism–mechanism and function
- (2011) Alison B. Kohan et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Interactions between CD36 and global intestinal alkaline phosphatase in mouse small intestine and effects of high-fat diet
- (2011) Matthew Lynes et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Niemann-Pick C1-Like 1 (NPC1L1) Protein in Intestinal and Hepatic Cholesterol Transport
- (2011) Lin Jia et al. Annual Review of Physiology
- Fenofibrate, a peroxisome proliferator-activated receptor α agonist, alters triglyceride metabolism in enterocytes of mice
- (2011) Aki Uchida et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- The proteome of cytosolic lipid droplets isolated from differentiated Caco-2/TC7 enterocytes reveals cell-specific characteristics
- (2011) Julien Bouchoux et al. BIOLOGY OF THE CELL
- Cholesterol esterification by ACAT2 is essential for efficient intestinal cholesterol absorption: evidence from thoracic lymph duct cannulation
- (2011) Tam M. Nguyen et al. JOURNAL OF LIPID RESEARCH
- The Acyl CoenzymeA:Monoacylglycerol Acyltransferase 3 (MGAT3) Gene is a Pseudogene in Mice but Encodes a Functional Enzyme in Rats
- (2011) Yong Gang Yue et al. LIPIDS
- Using the lymphatics to study nutrient absorption and the secretion of gastrointestinal hormones
- (2011) Alison B. Kohan et al. PHYSIOLOGY & BEHAVIOR
- Discovery of PF-04620110, a Potent, Selective, and Orally Bioavailable Inhibitor of DGAT-1
- (2011) Robert L. Dow et al. ACS Medicinal Chemistry Letters
- Molecular Characterization of the NPC1L1 Variants Identified from Cholesterol Low Absorbers
- (2010) Li-Juan Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A novel multiprotein complex is required to generate the prechylomicron transport vesicle from intestinal ER
- (2010) Shahzad Siddiqi et al. JOURNAL OF LIPID RESEARCH
- JTT-130, a Novel Intestine-Specific Inhibitor of Microsomal Triglyceride Transfer Protein, Suppresses Food Intake and Gastric Emptying with the Elevation of Plasma Peptide YY and Glucagon-Like Peptide-1 in a Dietary Fat-Dependent Manner
- (2010) T. Hata et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Vitamin E and neurological function
- (2010) David P. R. Muller MOLECULAR NUTRITION & FOOD RESEARCH
- Flotillins play an essential role in Niemann-Pick C1-like 1-mediated cholesterol uptake
- (2010) L. Ge et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cytosolic phospholipase A2-driven PGE2 synthesis within unsaturated fatty acids-induced lipid bodies of epithelial cells☆
- (2009) Luciana S. Moreira et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Differential association of adipophilin and TIP47 proteins with cytoplasmic lipid droplets in mouse enterocytes during dietary fat absorption
- (2009) Bonggi Lee et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Activation of the Liver X Receptor Stimulates Trans-intestinal Excretion of Plasma Cholesterol
- (2009) Jelske N. van der Veen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A dynamic, cytoplasmic triacylglycerol pool in enterocytes revealed by ex vivo and in vivo coherent anti-Stokes Raman scattering imaging
- (2009) Jiabin Zhu et al. JOURNAL OF LIPID RESEARCH
- Sec24C is required for docking the prechylomicron transport vesicle with the Golgi
- (2009) Shahzad Siddiqi et al. JOURNAL OF LIPID RESEARCH
- Peroxisome proliferator-activated receptor delta activation leads to increased transintestinal cholesterol efflux
- (2009) Carlos L. J. Vrins et al. JOURNAL OF LIPID RESEARCH
- Intestinal absorption of long-chain fatty acids: Evidence and uncertainties
- (2009) Isabelle Niot et al. PROGRESS IN LIPID RESEARCH
- The Emerging Functions and Mechanisms of Mammalian Fatty Acid–Binding Proteins
- (2008) Judith Storch et al. Annual Review of Nutrition
- The role of the small intestine in the development of dietary fat-induced obesity and insulin resistance in C57BL/6J mice
- (2008) Nicole JW de Wit et al. BMC Medical Genomics
- Lipid Bodies Are Reservoirs of Cyclooxygenase-2 and Sites of Prostaglandin-E2 Synthesis in Colon Cancer Cells
- (2008) M. T. Accioly et al. CANCER RESEARCH
- The Cholesterol Absorption Inhibitor Ezetimibe Acts by Blocking the Sterol-Induced Internalization of NPC1L1
- (2008) Liang Ge et al. Cell Metabolism
- Fatty acid transport protein 4 is dispensable for intestinal lipid absorption in mice
- (2008) Jien Shim et al. JOURNAL OF LIPID RESEARCH
- Metabolism of apical versus basolateralsn-2-monoacylglycerol and fatty acids in rodent small intestine
- (2008) Judith Storch et al. JOURNAL OF LIPID RESEARCH
- Reconstituting Initial Events during the Assembly of Apolipoprotein B-Containing Lipoproteins in a Cell-Free System
- (2008) Z. Gordon Jiang et al. JOURNAL OF MOLECULAR BIOLOGY
- Vascular Effects of Diet Supplementation With Plant Sterols
- (2008) Oliver Weingärtner et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Anderson or chylomicron retention disease: Molecular impact of five mutations in the SAR1B gene on the structure and the functionality of Sar1b protein
- (2007) Mathilde Charcosset et al. MOLECULAR GENETICS AND METABOLISM
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