The Origin and Contribution of Cancer-Associated Fibroblasts in Colorectal Carcinogenesis

Perivenous stellate cells are the main source of myofibroblasts and cancer‐associated‐fibroblasts formed after chronic liver injuries

(2021) Shan‐Shan Wang et al.   HEPATOLOGY

Lineage-dependent gene expression programs influence the immune landscape of colorectal cancer

(2020) Hae-Ock Lee et al.   NATURE GENETICS

Stromal cell diversity associated with immune evasion in human triple‐negative breast cancer

(2020) Sunny Z Wu et al.   EMBO JOURNAL

Single-cell transcriptomic architecture and intercellular crosstalk of human intrahepatic cholangiocarcinoma

(2020) Min Zhang et al.   JOURNAL OF HEPATOLOGY

The Balance of Stromal BMP Signaling Mediated by GREM1 and ISLR Drives Colorectal Carcinogenesis

(2020) Hiroki Kobayashi et al.   GASTROENTEROLOGY

Cancer-associated fibroblasts in gastrointestinal cancer

(2019) Hiroki Kobayashi et al.   Nature Reviews Gastroenterology & Hepatology

Interleukin-34, a comprehensive review

(2018) Muhammad Baghdadi et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Bone marrow–derived fibroblasts are a functionally distinct stromal cell population in breast cancer

(2018) Yael Raz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing

(2018) Michael Bartoschek et al.   Nature Communications

IL-1-induced JAK/STAT signaling is antagonized by TGF-beta to shape CAF heterogeneity in pancreatic ductal adenocarcinoma

(2018) Giulia Biffi et al.   Cancer Discovery

Leptin-receptor-expressing bone marrow stromal cells are myofibroblasts in primary myelofibrosis

(2017) Matthew Decker et al.   NATURE CELL BIOLOGY

Cancer stem cells revisited

(2017) Eduard Batlle et al.   NATURE MEDICINE

Fibroblast Subtypes Regulate Responsiveness of Luminal Breast Cancer to Estrogen

(2016) Heather M. Brechbuhl et al.   CLINICAL CANCER RESEARCH

The NF-κB family: Key players during embryonic development and HSC emergence

(2016) Raquel Espín-Palazón et al.   EXPERIMENTAL HEMATOLOGY

Tumor-associated fibroblasts predominantly come from local and not circulating precursors

(2016) Ainhoa Arina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gremlin 1 Identifies a Skeletal Stem Cell with Bone, Cartilage, and Reticular Stromal Potential

(2015) Daniel L. Worthley et al.   CELL

IKKβ in intestinal mesenchymal cells promotes initiation of colitis-associated cancer

(2015) Vasiliki Koliaraki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The consensus molecular subtypes of colorectal cancer

(2015) Justin Guinney et al.   NATURE MEDICINE

Targeting Endothelial CD146 Attenuates Colitis and Prevents Colitis-Associated Carcinogenesis

(2014) Shu Xing et al.   AMERICAN JOURNAL OF PATHOLOGY

Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival

(2014) Berna C. Özdemir et al.   CANCER CELL

Leptin-Receptor-Expressing Mesenchymal Stromal Cells Represent the Main Source of Bone Formed by Adult Bone Marrow

(2014) Bo O. Zhou et al.   Cell Stem Cell

Perivascular support of human hematopoietic stem/progenitor cells

(2013) M. Corselli et al.   BLOOD

CD146 Protein as a Marker to Predict Postoperative Liver Metastasis in Colorectal Cancer

(2013) Buxian Tian et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Proteome Profiling of Cancer-Associated Fibroblasts Identifies Novel Proinflammatory Signatures and Prognostic Markers for Colorectal Cancer

(2013) S. Torres et al.   CLINICAL CANCER RESEARCH

The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis

(2013) M. Reichert et al.   GENES & DEVELOPMENT

Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches

(2013) Lei Ding et al.   NATURE

EMT and Dissemination Precede Pancreatic Tumor Formation

(2012) Andrew D. Rhim et al.   CELL

Bone Marrow-Derived Myofibroblasts Contribute to the Mesenchymal Stem Cell Niche and Promote Tumor Growth

(2011) Michael Quante et al.   CANCER CELL

Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner

(2010) Neta Erez et al.   CANCER CELL

Human Gastrointestinal Neoplasia-Associated Myofibroblasts Can Develop from Bone Marrow-Derived Cells Following Allogeneic Stem Cell Transplantation

(2009) Daniel L. Worthley et al.   STEM CELLS