Elabela alleviates ferroptosis, myocardial remodeling, fibrosis and heart dysfunction in hypertensive mice by modulating the IL-6/STAT3/GPX4 signaling

Elabela prevents angiotensin II-induced apoptosis and inflammation in rat aortic adventitial fibroblasts via the activation of FGF21–ACE2 signaling

(2021) Juan-Juan Song et al.   JOURNAL OF MOLECULAR HISTOLOGY

Loss of Cardiac Ferritin H Facilitates Cardiomyopathy via Slc7a11-Mediated Ferroptosis

(2020) Xuexian Fang et al.   CIRCULATION RESEARCH

Inhibition of ferroptosis alleviates atherosclerosis through attenuating lipid peroxidation and endothelial dysfunction in mouse aortic endothelial cell

(2020) Tao Bai et al.   FREE RADICAL BIOLOGY AND MEDICINE

Angiotensin II Decreases Endothelial Nitric Oxide Synthase Phosphorylation via AT1R Nox/ROS/PP2A Pathway

(2020) Jing Ding et al.   Frontiers in Physiology

Ferrostatin-1 alleviates angiotensin II (Ang II)- induced inflammation and ferroptosis in astrocytes

(2020) Sijia Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Bazedoxifene exhibits anti-inflammation and anti-atherosclerotic effects via inhibition of IL-6/IL-6R/STAT3 signaling

(2020) Pengcheng Luo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Nrf2 deficiency aggravates Angiotensin II-induced cardiac injury by increasing hypertrophy and enhancing IL-6/STAT3-dependent inflammation

(2019) Dandan Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis

(2019) Matthew Dodson et al.   Redox Biology

Ferroptosis as a target for protection against cardiomyopathy

(2019) Xuexian Fang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endothelial Foxp1 Regulates Pathological Cardiac Remodeling Through TGF-β1-Endothelin-1 Signal Pathway

(2019) Jie Liu et al.   CIRCULATION

Cardiac endothelial cell transcriptome in neonatal, adult, and remodeling hearts

(2019) Zarha Vermeulen et al.   PHYSIOLOGICAL GENOMICS

Inhibiting Fibronectin Attenuates Fibrosis and Improves Cardiac Function in a Model of Heart Failure

(2018) Iñigo Valiente-Alandi et al.   CIRCULATION

Cardiac Remodeling: Endothelial Cells Have More to Say Than Just NO

(2018) Vincent F. M. Segers et al.   Frontiers in Physiology

Role of GPX4 in ferroptosis and its pharmacological implication

(2018) Tobias M. Seibt et al.   FREE RADICAL BIOLOGY AND MEDICINE

Myocardial Remodeling in Hypertension

(2018) Arantxa González et al.   HYPERTENSION

Apelin Is a Negative Regulator of Angiotensin II–Mediated Adverse Myocardial Remodeling and DysfunctionNovelty and Significance

(2017) Zhen-Zhou Zhang et al.   HYPERTENSION

The Effect of Velvet Antler Proteins on Cardiac Microvascular Endothelial Cells Challenged with Ischemia-Hypoxia

(2017) Xiang Xiao et al.   Frontiers in Pharmacology

Physiological and pathological cardiac hypertrophy

(2016) Ippei Shimizu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Heart Failure with Preserved Ejection Fraction

(2016) Margaret M. Redfield   NEW ENGLAND JOURNAL OF MEDICINE

A Novel Paradigm for Heart Failure With Preserved Ejection Fraction

(2013) Walter J. Paulus et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Cardiac protective effects of irbesartan via the PPAR-gamma signaling pathway in angiotensin-converting enzyme 2-deficient mice

(2013) Zhen-Zhou Zhang et al.   Journal of Translational Medicine

Angiotensin-converting enzyme 2 attenuates oxidative stress and VSMC proliferation via the JAK2/STAT3/SOCS3 and profilin-1/MAPK signaling pathways

(2013) Bei Song et al.   REGULATORY PEPTIDES

Angiotensin-Converting Enzyme 2 Suppresses Pathological Hypertrophy, Myocardial Fibrosis, and Cardiac Dysfunction

(2010) JiuChang Zhong et al.   CIRCULATION

Potential Therapeutic Targets for Cardiac Fibrosis

(2010) Andrew Leask   CIRCULATION RESEARCH

Telmisartan attenuates aortic hypertrophy in hypertensive rats by the modulation of ACE2 and profilin-1 expression

(2010) Jiu-Chang Zhong et al.   REGULATORY PEPTIDES

Role of nuclear unphosphorylated STAT3 in angiotensin II type 1 receptor-induced cardiac hypertrophy

(2009) Hong Yue et al.   CARDIOVASCULAR RESEARCH