Loss of Cardiac Ferritin H Facilitates Cardiomyopathy via Slc7a11-Mediated Ferroptosis

Ferroptosis as a target for protection against cardiomyopathy

(2019) Xuexian Fang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intravenous iron therapy in heart failure: a different perspective

(2019) Kambiz Ghafourian et al.   EUROPEAN JOURNAL OF HEART FAILURE

Anemia and Iron Deficiency in Heart Failure

(2018) Inder S. Anand et al.   CIRCULATION

Characterization of ferroptosis in murine models of hemochromatosis

(2017) Hao Wang et al.   HEPATOLOGY

Heart failure

(2017) Marco Metra et al.   LANCET

Autophagy promotes ferroptosis by degradation of ferritin

(2016) Wen Hou et al.   Autophagy

Ferroptosis: process and function

(2016) Y Xie et al.   CELL DEATH AND DIFFERENTIATION

Ferroptosis is an autophagic cell death process

(2016) Minghui Gao et al.   CELL RESEARCH

Ferritin levels and risk of heart failure-the Atherosclerosis Risk in Communities Study

(2016) Odilson M. Silvestre et al.   EUROPEAN JOURNAL OF HEART FAILURE

Benzoyl chloride derivatization with liquid chromatography–mass spectrometry for targeted metabolomics of neurochemicals in biological samples

(2016) Jenny-Marie T Wong et al.   JOURNAL OF CHROMATOGRAPHY A

15-Lipoxygenase metabolites of α-linolenic acid, [13-(S)-HPOTrE and 13-(S)-HOTrE], mediate anti-inflammatory effects by inactivating NLRP3 inflammasome

(2016) Naresh Kumar et al.   Scientific Reports

Regulation of Signal Transduction by Reactive Oxygen Species in the Cardiovascular System

(2015) D. I. Brown et al.   CIRCULATION RESEARCH

Lung congestion in chronic heart failure: haemodynamic, clinical, and prognostic implications

(2015) Vojtech Melenovsky et al.   EUROPEAN JOURNAL OF HEART FAILURE

Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

(2015) Xiaofang Sun et al.   HEPATOLOGY

Cardiomyocyte-specific deletion of ferroportin using MCK-Cre has no apparent effect on cardiac iron homeostasis

(2015) Xuexian Fang et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Glutaminolysis and Transferrin Regulate Ferroptosis

(2015) Minghui Gao et al.   MOLECULAR CELL

Ferroptosis as a p53-mediated activity during tumour suppression

(2015) Le Jiang et al.   NATURE

Iron deficiency and cardiovascular disease

(2015) Stephan von Haehling et al.   Nature Reviews Cardiology

Dietary intake of heme iron and risk of cardiovascular disease: A dose–response meta-analysis of prospective cohort studies

(2015) X. Fang et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Cardiac ferroportin regulates cellular iron homeostasis and is important for cardiac function

(2015) Samira Lakhal-Littleton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lethal Cardiomyopathy in Mice Lacking Transferrin Receptor in the Heart

(2015) Wenjing Xu et al.   Cell Reports

Systemic and Cerebral Iron Homeostasis in Ferritin Knock-Out Mice

(2015) Wei Li et al.   PLoS One

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Cardiac Markers of Myocardial Necrosis

(2014) Kent B. Lewandrowski   CLINICS IN LABORATORY MEDICINE

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

(2014) Joseph D. Mancias et al.   NATURE

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

(2014) Jose Pedro Friedmann Angeli et al.   NATURE CELL BIOLOGY

The IRP/IRE system in vivo: insights from mouse models

(2014) Nicole Wilkinson et al.   Frontiers in Pharmacology

Coupling Heme and Iron Metabolism via Ferritin H Chain

(2013) Raffaella Gozzelino et al.   ANTIOXIDANTS & REDOX SIGNALING

Proximal tubule H-ferritin mediates iron trafficking in acute kidney injury

(2013) Abolfazl Zarjou et al.   JOURNAL OF CLINICAL INVESTIGATION

Systemic Iron Homeostasis

(2013) Tomas Ganz   PHYSIOLOGICAL REVIEWS

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Metalloreductase Steap3 coordinates the regulation of iron homeostasis and inflammatory responses

(2012) F. Zhang et al.   HAEMATOLOGICA

Iron Overload in Human Disease

(2012) Robert E. Fleming et al.   NEW ENGLAND JOURNAL OF MEDICINE

Iron overload thalassemic cardiomyopathy: Iron status assessment and mechanisms of mechanical and electrical disturbance due to iron toxicity

(2011) Suree Lekawanvijit et al.   CANADIAN JOURNAL OF CARDIOLOGY

A new approach to the ferritin iron core growth: influence of the H/L ratio on the core shape

(2011) J. D. López-Castro et al.   DALTON TRANSACTIONS

Myocardial and Systemic Iron Depletion in Heart Failure

(2011) Micha T. Maeder et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Two to Tango: Regulation of Mammalian Iron Metabolism

(2010) Matthias W. Hentze et al.   CELL

Intestinal Ferritin H Is Required for an Accurate Control of Iron Absorption

(2010) Liviu Vanoaica et al.   Cell Metabolism

Hereditary Hemochromatosis: Pathogenesis, Diagnosis, and Treatment

(2010) Antonello Pietrangelo   GASTROENTEROLOGY

Iron Overload Cardiomyopathy

(2010) Pradeep Gujja et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Molecular distinction between physiological and pathological cardiac hypertrophy: Experimental findings and therapeutic strategies

(2010) Bianca C. Bernardo et al.   PHARMACOLOGY & THERAPEUTICS

Conditional deletion of ferritin H in mice induces loss of iron storage and liver damage

(2009) Deepak Darshan et al.   HEPATOLOGY

Ferric Carboxymaltose in Patients with Heart Failure and Iron Deficiency

(2009) Stefan D. Anker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Synthetic Lethal Screening Identifies Compounds Activating Iron-Dependent, Nonapoptotic Cell Death in Oncogenic-RAS-Harboring Cancer Cells

(2008) Wan Seok Yang et al.   CHEMISTRY & BIOLOGY