GPX4 degradation via chaperone-mediated autophagy contributes to antimony-triggered neuronal ferroptosis

Legumain promotes tubular ferroptosis by facilitating chaperone-mediated autophagy of GPX4 in AKI

(2021) Chuan’ai Chen et al.   Cell Death & Disease

Acid sphingomyelinase-dependent autophagic degradation of GPX4 is critical for the execution of ferroptosis

(2021) Faisal Thayyullathil et al.   Cell Death & Disease

Arsenite induces ferroptosis in the neuronal cells via activation of ferritinophagy

(2021) Junting Xiao et al.   FOOD AND CHEMICAL TOXICOLOGY

Arsenic and antimony co-induced nephrotoxicity via autophagy and pyroptosis through ROS-mediated pathway in vivo and in vitro

(2021) Fang Wan et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

PLASMA LEVEL OF ANTIMONY CORRELATES WITH PULMONARY HYPERTENSION SEVERITY

(2021) KARIM EL-KERSH et al.   CHEST

Antimony contamination and its risk management in complex environmental settings: A review

(2021) Nanthi Bolan et al.   ENVIRONMENT INTERNATIONAL

Chaperone-mediated autophagy and disease: Implications for cancer and neurodegeneration

(2021) Raquel Gómez-Sintes et al.   MOLECULAR ASPECTS OF MEDICINE

HDAC6-mediated Hsp90 deacetylation reduces aggregation and toxicity of the protein alpha-synuclein by regulating chaperone-mediated autophagy

(2021) Yunlan Du et al.   NEUROCHEMISTRY INTERNATIONAL

Antimony-induced astrocyte activation via mitogen-activated protein kinase activation-dependent CREB phosphorylation

(2021) Yudan Zheng et al.   TOXICOLOGY LETTERS

Iron Metabolism, Ferroptosis, and the Links With Alzheimer’s Disease

(2020) Nao Yan et al.   Frontiers in Neuroscience

Broad Spectrum Deubiquitinase Inhibition Induces Both Apoptosis and Ferroptosis in Cancer Cells

(2020) Li Yang et al.   Frontiers in Oncology

Akt inhibition-dependent downregulation of the Wnt/β-Catenin Signaling pathway contributes to antimony-induced neurotoxicity

(2020) Weiwei Shi et al.   SCIENCE OF THE TOTAL ENVIRONMENT

The effects of antimony on Alzheimer’s disease-like pathological changes in mice brain

(2020) Shenya Xu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Positive regulation of the CREB phosphorylation via JNK-dependent pathway prevents antimony-induced neuronal apoptosis in PC12 cell and mice brain

(2020) Ye Zhi et al.   NEUROTOXICOLOGY

Mean platelet volume mediated the relationships between heavy metals exposure and atherosclerotic cardiovascular disease risk: A community-based study

(2019) Chunmei Zhu et al.   European Journal of Preventive Cardiology

Chaperone-mediated autophagy is involved in the execution of ferroptosis

(2019) Zheming Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of chaperone-mediated autophagy in neurotoxicity induced by alpha-synuclein after methamphetamine exposure

(2019) Leping Sun et al.   Brain and Behavior

Antimony, a novel nerve poison, triggers neuronal autophagic death via reactive oxygen species-mediated inhibition of the protein kinase B/mammalian target of rapamycin pathway

(2019) Xiaoke Wang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Reactive Oxygen Species-Induced Lipid Peroxidation in Apoptosis, Autophagy, and Ferroptosis

(2019) Lian-Jiu Su et al.   Oxidative Medicine and Cellular Longevity

Insight into the mechanism of ferroptosis inhibition by ferrostatin-1

(2019) Giovanni Miotto et al.   Redox Biology

Antimony-Induced Neurobehavioral and Biochemical Perturbations in Mice

(2018) Tanzina Tanu et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

(2018) Lorenzo Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Role of GPX4 in ferroptosis and its pharmacological implication

(2018) Tobias M. Seibt et al.   FREE RADICAL BIOLOGY AND MEDICINE

Promotion of SIRT1 protein degradation and lower SIRT1 gene expression via reactive oxygen species is involved in Sb-induced apoptosis in BEAS-2b cells

(2018) Xinyuan Zhao et al.   TOXICOLOGY LETTERS

Antimony as a global dilemma: Geochemistry, mobility, fate and transport

(2017) Indika Herath et al.   ENVIRONMENTAL POLLUTION

Antimony and sleep-related disorders: NHANES 2005–2008

(2017) Franco Scinicariello et al.   ENVIRONMENTAL RESEARCH

Acetylation of translationally controlled tumor protein promotes its degradation through chaperone-mediated autophagy

(2017) Anne Bonhoure et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Antimony trichloride induces a loss of cell viability via reactive oxygen species-dependent autophagy in A549 cells

(2017) Xinyuan Zhao et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Ferroptosis Inhibition: Mechanisms and Opportunities

(2017) Jose Pedro Friedmann Angeli et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration

(2017) William Sealy Hambright et al.   Redox Biology

Oxidative stress in mice treated with antileishmanial meglumine antimoniate

(2013) D.B. Bento et al.   RESEARCH IN VETERINARY SCIENCE

Influence of microRNA deregulation on chaperone-mediated autophagy and α-synuclein pathology in Parkinson's disease

(2013) L Alvarez-Erviti et al.   Cell Death & Disease

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death

(2008) Alexander Seiler et al.   Cell Metabolism

The Chaperone-Mediated Autophagy Receptor Organizes in Dynamic Protein Complexes at the Lysosomal Membrane

(2008) U. Bandyopadhyay et al.   MOLECULAR AND CELLULAR BIOLOGY