Selective cleavage of ncRNA and antiviral activity by RNase2/EDN in THP1-induced macrophages

Angiogenin (ANG)—Ribonuclease Inhibitor (RNH1) System in Protein Synthesis and Disease

(2021) Mayuresh Anant Sarangdhar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

SLFN2 protection of tRNAs from stress-induced cleavage is essential for T cell–mediated immunity

(2021) Tao Yue et al.   SCIENCE

Eosinophils and COVID-19: diagnosis, prognosis, and vaccination strategies

(2021) Helene F. Rosenberg et al.   Seminars in Immunopathology

In lysate RNA digestion provides insights into the angiogenin’s specificity towards transfer RNAs

(2021) Yasutoshi Akiyama et al.   RNA Biology

Isolation and initial structure-functional characterization of endogenous tRNA-derived stress-induced RNAs

(2020) Yasutoshi Akiyama et al.   RNA Biology

Immune Sensing of Synthetic, Bacterial, and Protozoan RNA by Toll-like Receptor 8 Requires Coordinated Processing by RNase T2 and RNase 2

(2020) Thomas Ostendorf et al.   IMMUNITY

Oxidative stress enhances the expression of 2′,3′-cyclic phosphate-containing RNAs

(2020) Megumi Shigematsu et al.   RNA Biology

Non-Coding RNAs and Their Role in Respiratory Syncytial Virus (RSV) and Human Metapneumovirus (hMPV) Infections

(2020) Wenzhe Wu et al.   Viruses-Basel

Eosinophil Response Against Classical and Emerging Respiratory Viruses: COVID-19

(2020) JM Rodrigo-Muñoz et al.   JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY

The cell and stress‐specific canonical and noncanonical tRNA cleavage

(2020) Sherif Rashad et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Role of eosinophils in the diagnosis and prognostic evaluation of COVID‐19

(2020) Yingzheng Tan et al.   JOURNAL OF MEDICAL VIROLOGY

Human RNase3 immune modulation by catalytic-dependent and independent modes in a macrophage-cell line infection model

(2020) Lu Lu et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Importance of AGO 1 and 4 in Post-Transcriptional Gene Regulatory Function of tRF5-GluCTC, an Respiratory Syncytial Virus-Induced tRNA-Derived RNA Fragment

(2020) Eun-Jin Choi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Infection-induced 5′-half molecules of tRNAHisGUG activate Toll-like receptor 7

(2020) Kamlesh Pawar et al.   PLOS BIOLOGY

Role of Host tRNAs and Aminoacyl-tRNA Synthetases in Retroviral Replication

(2019) Danni Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential expression of human tRNA genes drives the abundance of tRNA-derived fragments

(2019) Adrian Gabriel Torres et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Antimicrobial RNases Inhibit Intracellular Bacterial Growth and Induce Autophagy in Mycobacteria-Infected Macrophages

(2019) Lu Lu et al.   Frontiers in Immunology

TLR8 Is a Sensor of RNase T2 Degradation Products

(2019) Wilhelm Greulich et al.   CELL

Angiogenin generates specific stress-induced tRNA halves and is not involved in tRF-3–mediated gene silencing

(2019) Zhangli Su et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleoside Tetra- and Pentaphosphates Prepared Using a Tetraphosphorylation Reagent Are Potent Inhibitors of Ribonuclease A

(2019) Scott M. Shepard et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genome-wide identification of short 2′,3′-cyclic phosphate-containing RNAs and their regulation in aging

(2019) Megumi Shigematsu et al.   PLoS Genetics

Evolutionary Trends in RNA Base Selectivity Within the RNase A Superfamily

(2019) Guillem Prats-Ejarque et al.   Frontiers in Pharmacology

Single-Cell Analysis of the Impact of Host Cell Heterogeneity on Infection with Foot-and-Mouth Disease Virus

(2018) Xiu Xin et al.   JOURNAL OF VIROLOGY

Human angiogenin is a potent cytotoxin in the absence of ribonuclease inhibitor

(2018) Sydney P. Thomas et al.   RNA

Immune Modulation by Human Secreted RNases at the Extracellular Space

(2018) Lu Lu et al.   Frontiers in Immunology

Monocytes and Macrophages as Viral Targets and Reservoirs

(2018) Ekaterina Nikitina et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Generation of 2′,3′-Cyclic Phosphate-Containing RNAs as a Hidden Layer of the Transcriptome

(2018) Megumi Shigematsu et al.   Frontiers in Genetics

Identification of two novel functional tRNA-derived fragments induced in response to respiratory syncytial virus infection

(2017) Jiehua Zhou et al.   JOURNAL OF GENERAL VIROLOGY

The emerging complexity of the tRNA world: mammalian tRNAs beyond protein synthesis

(2017) Paul Schimmel   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The first crystal structure of human RNase 6 reveals a novel substrate-binding and cleavage site arrangement

(2016) G. Prats-Ejarque et al.   BIOCHEMICAL JOURNAL

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure

(2016) Saumya Jain et al.   CELL

Selective amplification and sequencing of cyclic phosphate–containing RNAs by the cP-RNA-seq method

(2016) Shozo Honda et al.   Nature Protocols

Small RNA Modifications: Integral to Function and Disease

(2016) Xudong Zhang et al.   TRENDS IN MOLECULAR MEDICINE

Eosinophil-Derived Neurotoxin (EDN/RNase 2) and the Mouse Eosinophil-Associated RNases (mEars): Expanding Roles in Promoting Host Defense

(2015) Helene Rosenberg   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Respiratory Syncytial Virus Utilizes a tRNA Fragment to Suppress Antiviral Responses Through a Novel Targeting Mechanism

(2015) Junfang Deng et al.   MOLECULAR THERAPY

Small tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C

(2015) Sara R. Selitsky et al.   Scientific Reports

Immunostimulatory Defective Viral Genomes from Respiratory Syncytial Virus Promote a Strong Innate Antiviral Response during Infection in Mice and Humans

(2015) Yan Sun et al.   PLoS Pathogens

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Skewer: a fast and accurate adapter trimmer for next-generation sequencing paired-end reads

(2014) Hongshan Jiang et al.   BMC BIOINFORMATICS

The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones

(2014) Thomas R. Cech et al.   CELL

tRNA fragments in human health and disease

(2014) Paul Anderson et al.   FEBS LETTERS

Eosinophil Granule Proteins: Form and Function

(2014) K. Ravi Acharya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Metapneumovirus Infection Induces Significant Changes in Small Noncoding RNA Expression in Airway Epithelial Cells

(2014) Junfang Deng et al.   Molecular Therapy-Nucleic Acids

Eosinophil Cytokines, Chemokines, and Growth Factors: Emerging Roles in Immunity

(2014) Francis Davoine et al.   Frontiers in Immunology

Eosinophil-derived neurotoxin levels at 3 months post-respiratory syncytial virus bronchiolitis are a predictive biomarker of recurrent wheezing

(2013) Chang-Keun Kim et al.   BIOMARKERS

Generation of gene-modified mice via Cas9/RNA-mediated gene targeting

(2013) Bin Shen et al.   CELL RESEARCH

Respiratory Syncytial Virus—A Comprehensive Review

(2013) Andrea T. Borchers et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Ribonuclease/angiogenin inhibitor 1 regulates stress-induced subcellular localization of angiogenin to control growth and survival

(2013) E. Pizzo et al.   JOURNAL OF CELL SCIENCE

ShortStack: Comprehensive annotation and quantification of small RNA genes

(2013) M. J. Axtell   RNA

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection

(2013) Marloes Vissers et al.   Jove-Journal of Visualized Experiments

Nucleotide binding architecture for secreted cytotoxic endoribonucleases

(2012) Ester Boix et al.   BIOCHIMIE

Antimicrobial activity of human eosinophil granule proteins: involvement in host defence against pathogens

(2012) Anu Malik et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Inflammatory Responses to Respiratory Syncytial Virus (RSV) Infection and the Development of Immunomodulatory Pharmacotherapeutics

(2012) H. F. Rosenberg et al.   CURRENT MEDICINAL CHEMISTRY

An insertion in loop L7 of human eosinophil-derived neurotoxin is crucial for its antiviral activity

(2012) Deepa Sikriwal et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Identification and Functional Characterization of tRNA-derived RNA Fragments (tRFs) in Respiratory Syncytial Virus Infection

(2012) Qingrong Wang et al.   MOLECULAR THERAPY

Emerging role of angiogenin in stress response and cell survival under adverse conditions

(2011) Shuping Li et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Angiogenin-Induced tRNA Fragments Inhibit Translation Initiation

(2011) Pavel Ivanov et al.   MOLECULAR CELL

Viruses, microRNAs, and Host Interactions

(2010) Rebecca L. Skalsky et al.   Annual Review of Microbiology

Eosinophils in health and disease: the LIAR hypothesis

(2010) J. J. Lee et al.   CLINICAL AND EXPERIMENTAL ALLERGY

The eight human “canonical” ribonucleases: Molecular diversity, catalytic properties, and special biological actions of the enzyme proteins

(2010) Salvatore Sorrentino   FEBS LETTERS

Detection of RNA modifications

(2010) Stefanie Kellner et al.   RNA Biology

Respiratory viruses and eosinophils: Exploring the connections

(2009) Helene F. Rosenberg et al.   ANTIVIRAL RESEARCH

Influence of naturally-occurring 5′-pyrophosphate-linked substituents on the binding of adenylic inhibitors to ribonuclease a: An X-ray crystallographic study

(2009) Daniel E. Holloway et al.   BIOPOLYMERS

Ribonucleases as potential modalities in anticancer therapy

(2009) Wojciech Ardelt et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Angiogenin cleaves tRNA and promotes stress-induced translational repression

(2009) Satoshi Yamasaki et al.   JOURNAL OF CELL BIOLOGY

Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors

(2009) Robert H Kutner et al.   Nature Protocols

Small silencing RNAs: an expanding universe

(2009) Megha Ghildiyal et al.   NATURE REVIEWS GENETICS

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Eosinophil-Derived Neurotoxin / RNase 2: Connecting the Past, the Present and the Future

(2008) H. Rosenberg   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Stress induces tRNA cleavage by angiogenin in mammalian cells

(2008) Hanjiang Fu et al.   FEBS LETTERS

Structural Basis for Catalysis by Onconase

(2007) J. Eugene Lee et al.   JOURNAL OF MOLECULAR BIOLOGY