The role of NADPH oxidase 1 in alcohol-induced oxidative stress injury of intestinal epithelial cells

The Role of Short-Chain Fatty Acids and Bile Acids in Intestinal and Liver Function, Inflammation, and Carcinogenesis

(2021) Alexander Visekruna et al.   Frontiers in Cell and Developmental Biology

Natural polyphenols prevent indomethacin‐induced and diclofenac‐induced Caco‐2 cell death by reducing endoplasmic reticulum stress regardless of their direct reactive oxygen species scavenging capacity

(2020) Cherdsak Boonyong et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

DANGER SIGNALS IN LIVER INJURY AND RESTORATION OF HOMEOSTASIS

(2020) Hui Han et al.   JOURNAL OF HEPATOLOGY

Short-Chain Fatty Acids and Their Association with Signalling Pathways in Inflammation, Glucose and Lipid Metabolism

(2020) Jin He et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Health Benefits of Dietary Fibre

(2020) Thomas M. Barber et al.   Nutrients

Gut microbial metabolites in obesity, NAFLD and T2DM

(2019) Emanuel E. Canfora et al.   Nature Reviews Endocrinology

Alcohol, liver disease and the gut microbiota

(2019) Jasmohan S. Bajaj   Nature Reviews Gastroenterology & Hepatology

Microbiome as a therapeutic target in alcohol-related liver disease

(2019) Shiv K. Sarin et al.   JOURNAL OF HEPATOLOGY

Protein kinase B mediates insulin-like growth factor 1-induced phosphorylation and nuclear export of histone deacetylase 5 via NADPH oxidase 4 activation in vascular smooth muscle cells

(2019) Paulina Pietruczuk et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Medicinal prospects of antioxidants: A review

(2019) Kumari Neha et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Anthocyanins protect the gastrointestinal tract from high fat diet-induced alterations in redox signaling, barrier integrity and dysbiosis

(2019) Eleonora Cremonini et al.   Redox Biology

Metabolite-Sensing Receptor Ffar2 Regulates Colonic Group 3 Innate Lymphoid Cells and Gut Immunity

(2019) Eunyoung Chun et al.   IMMUNITY

The Candida albicans exotoxin candidalysin promotes alcohol-associated liver disease

(2019) Huikuan Chu et al.   JOURNAL OF HEPATOLOGY

The gut-liver axis in liver disease: pathophysiological basis for therapy

(2019) Agustín Albillos et al.   JOURNAL OF HEPATOLOGY

Combined Treatment with Three Natural Antioxidants Enhances Neuroprotection in a SH-SY5Y 3D Culture Model

(2019) Marrazzo et al.   Antioxidants

Megakaryocytic Leukemia 1 (MKL1) Bridges Epigenetic Activation of NADPH Oxidase in Macrophages to Cardiac Ischemia-Reperfusion Injury

(2018) Yu Liming et al.   CIRCULATION

Apoptosis of enterocytes and nitration of junctional complex proteins promote alcohol-induced gut leakiness and liver injury

(2018) Young-Eun Cho et al.   JOURNAL OF HEPATOLOGY

NADPH oxidases and ROS signaling in the gastrointestinal tract

(2018) Gabriella Aviello et al.   Mucosal Immunology

(-)-Epicatechin protects the intestinal barrier from high fat diet-induced permeabilization: Implications for steatosis and insulin resistance

(2018) Eleonora Cremonini et al.   Redox Biology

Epigenetic regulation of vascular NADPH oxidase expression and reactive oxygen species production by histone deacetylase-dependent mechanisms in experimental diabetes

(2018) Simona-Adriana Manea et al.   Redox Biology

Alcohol use and burden for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

(2018) Max G Griswold et al.   LANCET

Bacteria engineered to produce IL-22 in intestine induce expression of REG3G to reduce ethanol-induced liver disease in mice

(2018) Tim Hendrikx et al.   GUT

Butyrate modifies intestinal barrier function in IPEC-J2 cells through a selective upregulation of tight junction proteins and activation of the Akt signaling pathway

(2017) Hui Yan et al.   PLoS One

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

(2016) Ara Koh et al.   CELL

Inhibition of histone deacetylase reduces transcription of NADPH oxidases and ROS production and ameliorates pulmonary arterial hypertension

(2016) Feng Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Trichostatin A, a histone deacetylase inhibitor suppresses NADPH Oxidase 4-Derived Redox Signalling and Angiogenesis

(2016) Nora Y. Hakami et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The intestinal epithelial barrier: a therapeutic target?

(2016) Matthew A. Odenwald et al.   Nature Reviews Gastroenterology & Hepatology

Propionate Ameliorates Dextran Sodium Sulfate-Induced Colitis by Improving Intestinal Barrier Function and Reducing Inflammation and Oxidative Stress

(2016) Ling-chang Tong et al.   Frontiers in Pharmacology

Separation of intact intestinal epithelium from mesenchyme

(2016) Ali Moussavi Nik et al.   BIOTECHNIQUES

Alcoholic Liver Disease: The Gut Microbiome and Liver Cross Talk

(2015) Phillipp Hartmann et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Regulation of Oxidative Stress in Pulmonary Artery Endothelium. Modulation of Extracellular Superoxide Dismutase and NOX4 Expression Using Histone Deacetylase Class I Inhibitors

(2015) Igor N. Zelko et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Histone and Non-Histone Targets of Dietary Deacetylase Inhibitors

(2015) Eunah Kim et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Dysbiosis-induced intestinal inflammation activates tumor necrosis factor receptor I and mediates alcoholic liver disease in mice

(2015) Peng Chen et al.   HEPATOLOGY

Dietary Gut Microbial Metabolites, Short-chain Fatty Acids, and Host Metabolic Regulation

(2015) Mayu Kasubuchi et al.   Nutrients

Protective action of NADPH oxidase inhibitors and role of NADPH oxidase in pathogenesis of colon inflammation in mice

(2014) Rima Ramonaite   WORLD JOURNAL OF GASTROENTEROLOGY

Role for intestinal CYP2E1 in alcohol-induced circadian gene-mediated intestinal hyperpermeability

(2013) Christopher B. Forsyth et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis

(2013) Mohamed A. Abdelmegeed et al.   FREE RADICAL BIOLOGY AND MEDICINE

Short-Chain Fatty Acids Activate GPR41 and GPR43 on Intestinal Epithelial Cells to Promote Inflammatory Responses in Mice

(2013) Myung H. Kim et al.   GASTROENTEROLOGY

A Potential Suppressive Effect of Natural Antisense IL-1  RNA on Lipopolysaccharide-Induced IL-1  Expression

(2013) J. Lu et al.   JOURNAL OF IMMUNOLOGY

Mouse model of chronic and binge ethanol feeding (the NIAAA model)

(2013) Adeline Bertola et al.   Nature Protocols

Butyrate Enhances Intestinal Epithelial Barrier Function via Up-Regulation of Tight Junction Protein Claudin-1 Transcription

(2012) Hong-Bo Wang et al.   DIGESTIVE DISEASES AND SCIENCES

Host-Gut Microbiota Metabolic Interactions

(2012) J. K. Nicholson et al.   SCIENCE

Chronic alcohol-induced liver injury and oxidant stress are decreased in cytochrome P4502E1 knockout mice and restored in humanized cytochrome P4502E1 knock-in mice

(2010) Yongke Lu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Butyrate Enhances the Intestinal Barrier by Facilitating Tight Junction Assembly via Activation of AMP-Activated Protein Kinase in Caco-2 Cell Monolayers

(2009) Luying Peng et al.   JOURNAL OF NUTRITION

Butyrate-Induced Transcriptional Changes in Human Colonic Mucosa

(2009) Steven A. L. W. Vanhoutvin et al.   PLoS One

Butyrate modulates oxidative stress in the colonic mucosa of healthy humans

(2008) Henrike M. Hamer et al.   CLINICAL NUTRITION

Cytochrome P450 2E1 contributes to ethanol-induced fatty liver in mice

(2008) Yongke Lu et al.   HEPATOLOGY

Evidence that chronic alcohol exposure promotes intestinal oxidative stress, intestinal hyperpermeability and endotoxemia prior to development of alcoholic steatohepatitis in rats

(2008) Ali Keshavarzian et al.   JOURNAL OF HEPATOLOGY